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Papillary Thyroid Cancer (PTC) is the most common and differentiated form of thyroid malignancy, representing roughly 80% of all cases. It develops in the follicular cells of the thyroid gland—the butterfly-shaped organ at the base of the neck. PTC is characterized by its slow progression and unique microscopic features, such as "Orphan Annie eye" nuclei and Psammoma bodies.

While it has a high tendency to spread to the lymph nodes in the neck (cervical metastasis), it remains one of the most curable forms of cancer. Primary treatment usually involves a total or partial thyroidectomy, followed by radioactive iodine (RAI) therapy in specific cases to eliminate remaining cancerous cells. Due to its slow-growing nature, the long-term survival rate is exceptionally high.