Aacef 250mg Injection

Aacef injection contains ceftriaxone, an antibiotic belonging to the Cephalosporin class. It is indicated for the treatment of severe bacterial infections affecting various body systems, including the brain, lungs, ear, stomach, urinary tract, joints, and skin. It is also utilized in surgical procedures to prevent potential post-operative infections.

Ceftriaxone exerts its antibacterial effect by inhibiting the synthesis of the bacterial cell wall, which is essential for bacterial survival and replication, thereby leading to the elimination of the infection-causing bacteria. Administration of Aacef injection occurs in a hospital environment under the direct supervision of a medical professional, such as a doctor or nurse. It is administered either as an intravenous infusion (drip) or as a direct injection into a vein or a muscle.

Self-administration of this medication is not advised. The appropriate dosage is determined by the healthcare provider based on the specific infection and its severity. Possible side effects include diarrhoea, alterations in blood test results, localized pain at the injection site, headache, and dizziness.

While these effects typically resolve on their own, it is important to inform a doctor if they persist or intensify.

Dosage

Missed a Dose

• You will be monitored by your doctor or nurse on when Aacef injection should be given to you.
• It is unlikely that the dose will be missed.
• However, if you think your doctor or nurse might have missed a dose, inform them.
• It is advisable not to miss any dose of antibiotics as it can fail therapy.

Overdose

• Your doctor or nurse will give Aacef injection, therefore chances of an overdose are rare.
• However, if you experience nausea, vomiting, diarrhoea and stomach upset immediately after taking this injection, inform your doctor or reach out to your nearest hospital as soon as possible.

Mode of Action

How Does It Work?

It works by inhibiting the formation of the bacterial cell wall, thereby killing the bacteria and preventing infection.

Directions for Use

• Aacef injection will be given to you in the hospital by your doctor or nurse. Do not self-inject this medicine.
• Follow any instructions suggested by the doctor or nurse during the procedure or for aftercare.

Precautions and Warnings

Pregnancy

Can I take Aacef injection during pregnancy?

Since there is limited safety data available on the use of Aacef injection in pregnant women, Aacef injection must only be used during pregnancy (in particular in the first trimester of pregnancy) if considered essential by your doctor after assessing the benefits over risks.

Breast Feeding

Can I take Aacef injection while breastfeeding?

• Components of Aacef injection pass into breast milk. Inform your doctor if you are breastfeeding, your doctor will tell you about the use of this medicine after assessing the need and benefit.
• If prescribed, monitor your child closely for antibiotic-related side effects like diarrhoea or fungal infection of the mouth.

Driving

Can I drive if I have consumed Aacef injection?

You may feel dizzy after taking Aacef injection, thus be cautious or avoid driving after taking this injection.

Alcohol

Can I consume alcohol with Aacef injection?

Alcohol may worsen the side effect like dizziness along with Aacef injection . It is advisable to avoid alcohol.

Other General Warnings

Talk to your doctor if

• You have liver diseases.
• You have kidney diseases or kidney stones.
• You are suffering from gallstones.
• You are suffering from anaemia (which reduces red blood cells).
• You are suffering from bowel inflammation.
• You have a stomach disease or problems like diarrhoea after taking antibiotics.
• You have recently taken any medicine containing calcium.
• Planning to get a blood test? It may interfere with the results.
• Aacef injection should not be given to premature babies.

Contraindications

• If you are allergic to Ceftriaxone or any other ingredients of Aacef injection.
• If you are allergic to a class of medicines known as cephalosporin.
• If you are allergic to medicines like penicillins, monobactams and carbapenems.
• If a newborn is suffering from jaundice or is on calcium injection treatment.
• If a newborn is suffering from increased bilirubin in the blood.
• Ceftriaxone solution containing lidocaine should not be given as an injection.

Side effects

• Increased number of eosinophils
• Diarrhoea, loose stools
• Increased liver enzymes
• Rash
• Fungal infections
• A decrease in white blood cells
• Decreased red blood cells (anaemia)
• A bleeding disorder like coagulopathy (a condition in which the ability of blood to form clots is decreased)
• Headache
• Dizziness
• Nausea
• Vomiting
• Itching at the injection site
• Pain at the injection site
• Fever
• Increased creatinine levels in the blood

Interactions

Interactions with other medicines

• Some medicines can affect the way the Aacef injection works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
• Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.
• Aacef injection should never be given along with Ringer's or Hartmann's solution.
• This injection alters the action of oral contraceptives. Thus it is advisable to use alternative contraceptive measures like condoms when you are taking this medicine.
• Aacef injection should never be given through the IV line through which calcium-containing solutions are given.

Frequently Asked Questions (FAQs)

For how long do I need to take this Aacef injection?

You are supposed to complete the prescribed duration of antibiotics by your doctor. Otherwise, there is a possibility of reoccurrence of the infection.

Can the use of Aacef injection cause diarrhoea?

Yes, the use of Aacef injection can cause diarrhoea along with the desired effect, but not everyone gets them. It is an antibiotic that kills both good and bad bacteria, when good bacteria present in the intestine gets killed it can cause diarrhoea. If you are experiencing severe diarrhoea, talk to your doctor about it.

Can the Aacef injection use to treat urinary tract infection (UTI)?

Yes, the Aacef injection can be used to treat urinary tract infection (UTI) caused by infection-causing bacteria. Your doctor may prescribe you this medicine based on the condition of your infection and its severity.

What is the dose of Aacef injection ?

The dose and duration of the treatment with Aacef injection will be decided by the doctor. It should be given till the time you see an improvement in your health conditions.

How do I use Aacef injection ?

Aacef injection will be given to you by a doctor or nurse. You should avoid self-injecting. Follow any instructions suggested by the doctor or nurse during the procedure or for aftercare.

What Aacef injection is used for?

Aacef injection is mainly used before surgeries to prevent infection which may arise post-surgery like vaginal or abdominal surgeries to remove the uterus, surgery to remove gall bladder stone or for jaundice, etc.