Activa 25 Mg/1ml Injection 30 Ml

Activa Injection is a medication used to alleviate pain and inflammation. It contains diclofenac as the active ingredient. This medicine is used to relieve acute pain associated with rheumatoid arthritis, gout, and pain following surgery, as well as discomfort arising from dental procedures and trauma.

It works by inhibiting the production of prostaglandin, a chemical responsible for the sensation of pain, swelling, and inflammation. The medication will be administered as an Injection by a healthcare professional in a hospital or clinic. The dosage and duration of treatment depend on the underlying condition.

Before starting treatment, you should inform the doctor if you smoke, have diabetes, a blood clotting disorder, a heart condition, or similar issues.

Dosage

Overdose

Activa Injection will be given by a doctor or nurse thus the chances of an overdose are unlikely. You may experience headache, nausea, vomiting, stomach pain, diarrhoea, unconsciousness, excitation, dizziness, drowsiness. Inform the doctor or seek medical help.

Missed a Dose

It is unlikely that a dose of the Injection will be missed if you are monitored in a healthcare setup. However, if you have missed taking a dose of the Injection, inform the doctor or nurse immediately.

Mode of Action

How Does It Work?

Activa Injection interfere with the production of a chemical called prostaglandins, which is responsible for the sensation of pain and swelling. It reduces pain and swelling.

Directions for Use

• Activa Injection will be given to you in a hospital by the doctor or nurse as an Injection.
• Do not self-inject the medicine. Follow the aftercare instruction given by the doctor.

Precautions and Warnings

Pregnancy

Can I take Activa Injection during pregnancy?

Due to lack of safety information this medicine is not recommended in pregnant women, especially during the last trimester of pregnancy. If you think you are pregnant or think you may be pregnant, seek immediate medical advice.

Breast Feeding

Can I take Activa Injection while breastfeeding?

Due to lack of safety information this medicine is not recommended during breastfeeding.

Driving

Can I drive if I have taken Activa Injection?

Avoid driving if you experience dizziness, visual disturbance, spinning head, sleepiness, or drowsiness while on treatment.

Alcohol

Can I consume alcohol with Activa Injection?

Although there is no known interaction with alcohol and Activa Injection, it is essential to consult the physician if you have a habit of regular drinking. Consuming alcohol while taking pain killers is known to increase the risk of bleeding, ulcer and perforation in the stomach and intestine (upper gastrointestinal tract).

Other General Warnings

Talk to your doctor if

• You are already using other painkillers.
• Your kidneys are not working properly and you experience swelling and water retention.
• You suffer from skin rashes, itching, papules, blisters, etc.
• You have a hereditary disorder of intolerance to some sugars like lactose and glucose.
• You suffer from autoimmune disorders like systemic lupus erythematosus.
• You are trying to conceive or taking treatment for infertility, should discontinue the medicine.
• You have asthma, or you are prone to seasonal allergies, rhinitis, and other lung and throat problems.
• You have a history of stomach or bowel disorders like gastrointestinal bleeding or Crohn's disease.
• You are an elderly patient, or with low body weight, the doctor may reduce your dose of the medicine.
• You have liver disease, close monitoring of liver function is required.
• You have heart problems like high blood pressure, high cholesterol, or diabetes, or you are an active smoker.
• You may develop stomach or intestinal bleeding problems during the treatment, the risk is more if you are using aspirin.

Contraindications

• If you are allergic to diclofenac or its other ingredients.
• If you suffer from liver, heart, or kidney failure. If you have a history of a bleeding disorder or tend to bleed easily.
• If you have or have had an active stomach or intestinal ulcer or bleeding issues.
• If you have a history of stomach ulcers or bleeding due to the use of painkillers.
• If you have recently undergone surgery or an operation that carries a risk of bleeding.
• If you are pregnant, in your last trimester, have a history of asthma attacks, or are experiencing dehydration.
• If you are taking medication to prevent blood clots, such as heparin, or other pain relievers like ibuprofen, celecoxib, etc.
• If you have had an allergic reaction to painkillers, such as asthma, skin rashes, swelling, or nasal congestion.
• If you suffer from brain and heart conditions, such as heart attacks, strokes, heart failure, or circulation problems.

Side effects

• Injection site pain
• Tenderness
• Nausea
• Vomiting
• Diarrhoea
• Indigestion
• Bloating
• Headache
• Dizziness

Interactions

Interactions with other medicines

• Concomitant use of diclofenac with medicines like water pills and other blood pressure medicines like furosemide, propranolol, atenolol, and telmisartan decrease the blood pressure lowering effects and thus should be cautiously used in elderly patients.
• Water pills like chlorothiazide, chlorthalidone and immunosuppressants like tacrolimus and ciclosporin may increase the potassium level if taken along with Activa Injection.
• Concomitant use of anticoagulants like warfarin and medicines to treat brain conditions like escitalopram and fluoxetine increase the risk of bleeding and ulcers.
• Using antidiabetics along with the Injection affect the blood sugar level. The doctor may ask to monitor blood sugar levels regularly.
• Antibiotics like ciprofloxacin, norfloxacin cause fits (you may have a history of fits or seizures) if taken along with the medicine.
• Diclofenac must not be used for 10-12 days after the use of mifepristone, as it reduces the effect of the medicine.
• Other medicines like phenytoin for fits, sulfinpyrazone and voriconazole, colestipol, cholestyramine, lithium used to treat brain conditions and digoxin used to treat heart failure must be used cautiously.
• Inform the doctor about the other medicine, supplement or herbals you are taking or might take to avoid possible interaction.

Storage and disposal

• Store Activa Injection below 30°C at a cool and dry place away from direct sunlight.
• Keep it away from children and pets.

Frequently Asked Questions (FAQs)

What is the duration of the effect of the Injection?

It varies among individuals depending on the physiological nature of an individual. The effects last for 12 hours.

Is Activa Injection safe during pregnancy?

Avoid during pregnancy, in the third trimester of pregnancy. Consult the doctor for more information.

How to store Activa Injection?

Store the Injection below 30°C. Avoid using the unused portion once opened.