Addnok Sublingual Tablet

Addnok tablet is a prescription medicine used for managing symptoms caused due to addiction to opioid-related medication. It reduces withdrawal symptoms when the person suddenly stops using those medications. It is also used to manage moderate to severe pain, which is not responding to regular pain relievers that are not opioid-based.

Addnok tablet consists of Buprenorphine as its active ingredient. It belongs to the class of opioid or narcotic pain reliever medicines. It works by blocking the pain signals from reaching the injury site on the body.

It also increases certain chemical substances that help in reducing pain and producing a calming effect. This medicine does have some side effects. Most of them will subside and do not need any medical attention.

Consult a doctor if they persist. Addnok tablet should be used as advised by the doctor. Do not use this medicine if you are pregnant or breastfeeding without consulting your doctor.

This can also cause withdrawal symptoms like sweating, pain, nausea, vomiting, etc., if you stop using it for a long time. It may also lower fertility in men and women in rare cases.

Dosage

Overdose

Addnok tablet is supposed to be used precisely the way the doctor recommends. Using multiple tablets at once can lead to an overdose, which causes symptoms including abdominal pain, dizziness, fainting, vomiting, seizures, low blood sugar, sweating, changes in heartbeat, lethargy, low blood pressure, liver failure (yellow skin and eyes), confusion, and loss of consciousness. In case of Addnok tablet overdose, seek immediate medical treatment from the nearest medical centre.

Missed a Dose

If you missed a dose of the Addnok tablet, take it as soon as possible. If it's already time to take the next dose, skip the missed dose and take the next one. Do not take both doses together as it can cause an overdose. Talk to your doctor if you have any confusion about it.

Mode of Action

How Does It Work?

Addnok tablet consists of a single active ingredient: Buprenorphine. It belongs to the class of opioid or narcotic pain relievers. It helps to block the pain pathways in the nervous system by binding specific receptors. It also increases the amount of norepinephrine and serotonin, the chemical messengers responsible for reducing pain and causing a calming effect.

Directions for Use

• Try to take the Addnok tablet in the recommended dose and duration.
• Do not take more than a tablet at one time without informing the doctor, as this can lead to an overdose.
• Take it immediately after opening the pack.
• Swallow the tablet entirely with a glass of water, and do not chew.
• Try to take this medication on time.
• Try to take it with food to prevent stomach problems.
• Check the expiration date before using it.
• Consult your doctor if you want to give it to a child.

Precautions and Warnings

Pregnancy

Can I take the Addnok tablet during pregnancy?

No. Do not use an Addnok tablet without consulting a doctor if you are pregnant. Even though there are limited human studies, some studies have shown that they can treat opioid dependence in pregnant women. Please consult your doctor before using this medicine.

Breast Feeding

Can I take the Addnok tablet while breastfeeding?

Do not use the Addnok tablet without consulting a doctor if you are breastfeeding. Studies have shown that they can be used during breastfeeding, but only in prescribed doses. However, side effects like drowsiness, weight gain, developmental milestones should be monitored in the child, especially in newborns. Please consult your doctor.

Driving

Can I drive if I have taken the Addnok tablet?

Addnok tablets have Buprenorphine, which is an opioid analgesic (painkiller). It causes symptoms like dizziness, drowsiness, and blurred vision. Therefore, do not drive or operate heavy machinery, if you have experienced any of these effects.

Alcohol

Can I consume alcohol with the Addnok tablet?

No, it is better not to consume alcohol with the Addnok tablets. It can exaggerate the effects of alcohol. It can cause side effects like drowsiness, nausea, vomiting, unconsciousness, dizziness, etc.

Other General Warnings

Talk to your doctor if

• You are an elderly patient over 65 years of age; this medicine can increase side effects.
• You are planning to have surgery or a dental procedure.
• You are using any herbal or ayurvedic products or supplements like st john wort. The interaction can cause serious side effects.
• You have a head injury, seizure disorder, high blood pressure, stroke, and other conditions that can raise the pressure inside the skull.
• You have a history of kidney, liver, or thyroid conditions.
• You have a heart condition like heart rhythm problem, heart attack, etc.

Contraindications

• If you are allergic to any composing unit of Addnok tablets
• If you have been on certain antidepressant medications in the last two weeks.
• If you have respiratory depression, this medicine can cause severe depression and slows down respiration which can be life-threatening.
• If you are diagnosed with myasthenia gravis (a condition that causes muscle weakness). This medicine can worsen the condition.
• If you have breathing difficulties because of any chronic condition like asthma.
• If you are pregnant, this medicine can cause withdrawal symptoms in the child.
• If you are planning to get pregnant, this medicine may lower fertility in women.

Side effects

• Headache
• Dry mouth
• Stomach pain
• Difficulty staying asleep
• Nausea
• Vomiting
• Changes in heart rate
• Drowsiness

Interactions

Interactions with other medicines

• Do not use the Addnok tablet with other pain medications, as they can cause serious adverse effects. It can also damage the liver.
• If you are using this medicine with other medicine like allergy medications, cough or cold medicines, muscle relaxants, sleeping pills, etc., it can cause extreme drowsiness. Also, they can cause breathing problems which can be life-threatening.
• If you are using medicine like antidepressants, seizure medicines, heart medications, etc., notify your doctor to prevent side effects.

Interactions with food items

• There is not much information available on Addnok tablet interactions with food.
• Avoid grapefruit or its juice to avoid any interactions.

Storage and disposal

Store the Addnok tablet in dry conditions at room temperature. Keep it away from direct sunlight, humid conditions, and wet surfaces. Dispose of the packaging carefully after using it. Throw it away if the package has been already opened. Check the expiration date before taking the tablet. Do not use this medication if it's past the expiration date. Keep Addnok tablet away from children and pets.

Frequently Asked Questions (FAQs)

Can I use Addnok tablets if I have a history of addiction to certain drugs or alcohol?

Addnok tablets are used for managing symptoms caused by opioid-related medication addiction. This tablet helps manage withdrawal symptoms when the person suddenly stops using opioid or narcotic pain relievers and other medication. But, consult the doctor first if you have any dependency issues for proper treatment. Do not use this by yourself.

Can I use two Addnok tablets at same time if I am not noticing any changes?

No, do not use more than the recommended dose of Addnok tablets at once. It can cause an overdose. Consult your doctor first if your symptoms have not improved.

Can I use Addnok tablets in a child younger than 17 years of age?

Not many studies were conducted on the use of this medicine in children. The safety and efficacy of the medicine in children is not established. Please consult your doctor before giving this medicine to a child.