Ifoxan With Mesna 1gm Injection

Ifoxan With Mesna 1gm Injection contains Etoricoxib, a non-steroidal anti-inflammatory drug (NSAID).

Dosage

Overdose

If you think you have had an overdose of this medicine, contact your doctor immediately or visit the nearest hospital

Missed a Dose

• If you missed any dose, take it as soon as you remember
• If it is time for the next dose, skip the missed dose and continue your regular dosing schedule
• Do not take a double dose of medicine to compensate for a missed one

Mode of Action

How Does It Work?

Etoricoxib works by reducing the generation of Prostaglandins that are responsible for pain and inflammation in the body

Directions for Use

• Take this medicine as advised by your doctor
• Do not take more than the recommended dose
• Do not take it for more time than prescribed as there is risk of heart attack and strokes if taken for an extended period in high doses

Precautions and Warnings

Pregnancy

Can I take Ifoxan With Mesna 1gm Injection during pregnancy?

• Etoricoxib must not be taken during pregnancy
• If you are pregnant or think you can be pregnant, do not take this medicine

Breast Feeding

Can I take Ifoxan With Mesna 1gm Injection while breastfeeding?

It is unknown if Etoricoxib passes into human milk. However, this medicine should not be taken while breastfeeding.

Driving

Can I drive if I have consumed Ifoxan With Mesna 1gm Injection?

This medicine can cause dizziness, spinning sensation (vertigo) or sleepiness, if you experience any of these effects, it is advised not to drive or operate machines.

Alcohol

Can I consume alcohol with Ifoxan With Mesna 1gm Injection?

No information is available on interactions of this medicine when taken with alcohol. However, drinking alcohol while taking this medicine can worsen the side effects like dizziness.

Other General Warnings

Talk to your doctor if

• You are suffering from vomiting or diarrhea and are dehydrated
• You have a history of heart failure or other diseases related to heart
• You have swelling due to fluid retention (excess fluid in the body)
• You have high blood pressure; your doctor may need to check your blood pressure more often
• You are suffering from liver disease or kidney disease
• You are a diabetic, smoker or have high cholesterol as all these increase the chance of heart disease
• You are pregnant or breastfeeding
• You are an aged person (above 65 years)

Contraindications

• If you are allergic to Etoricoxib or any other ingredient of this medicine
• If you are taking Acetylsalicylic Acid (Aspirin) or NSAIDs including COX-2 inhibitors and are suffering from constriction of muscles in bronchioles, congestion or nasal discharge, nasal polyps (painless growth that develop in the lining of the nose, angioneurotic oedema (pain and swelling under the skin), urticaria or allergic-type reactions
• If you have severe liver or kidney disease
• If your age is below 16
• If you are suffering from stomach ulcers, bleeding from intestine or inflammatory bowel disease
• If you are pregnant or breast-feeding
• If you are suffering from congestive heart failure or heart diseases like ischaemic heart disease (condition when the heart is not getting enough blood and oxygen), peripheral arterial disease (circulatory problem in which narrowed arteries reduce blood flow to your limbs), or cerebrovascular disease (disorders that affect the blood vessels and blood supply to the brain)
• If you are suffering from uncontrolled high blood pressure

Side effects

• Stomach pain
• Swelling of legs or feet (oedema)
• Dizziness
• Headache
• Rapid heartbeat
• Shortness of breath or wheezing sound (bronchospasm)
• Constipation
• Excessive gas
• Diarrhea
• Indigestion
• Nausea
• Vomiting
• Mouth ulcers
• Bruises
• Tiredness

Interactions

Interactions with other medicines

• Blood-thinning medicines (anticoagulants) like Warfarin
• Rifampicin for various infections
• Medicines used to suppress the immune system and often used in rheumatoid arthritis like Methotrexate, Cyclosporin or Tacrolimus
• Antidepressants like Lithium
• High blood pressure and heart failure medicines like Enalapril and Ramipril, and Losartan and Valsartan
• Diuretics
• Heart failure and irregular heart rhythm medicines like Digoxin
• Asthma (Salbutamol tablets)
• Oral contraceptive pills
• Medicines used for hormone replacement therapy
• Aspirin

Interactions with food items

• Taking this medicine with food does not affect the way it works
• Ifoxan With Mesna 1gm Injection can be taken with or without food

Storage and disposal

• Ifoxan With Mesna 1gm Injection does not require any special storage conditions
• Try to keep out of the reach of children

Frequently Asked Questions (FAQs)

What should I consult with the doctor while taking Ifoxan With Mesna 1gm Injection?

• Inform your doctor if you have any infection because this medicine can mask the symptoms of a severe infection
• For osteoarthritis, weight control and regular exercising can increase muscle strength and reduce the load on joints

Can I take Aspirin when I am taking Ifoxan With Mesna 1gm Injection?

• Do not take high dose of Aspirin (above 300m) generally given for pain relief
• Taking this medicine along with such high doses of Aspirin can increase the risk of stomach ulcers
• If you are taking Aspirin for heart disease (generally low dose), do not discontinue on your own, inform your doctor