Amaryl M 2mg Tablet

Amaryl M 2mg tablet is an oral anti-diabetic medication. It contains glimepiride and metformin as its active ingredients. It is used for the treatment of type 2 diabetes mellitus, a condition in which blood sugar levels rise above the normal range and cannot be controlled by diet and exercise alone.

This medicine decreases elevated blood glucose levels. You must maintain a healthy diet and exercise along with the medication. Amaryl M 2mg must be taken as directed by the doctor, in prescribed doses and for the advised duration.

It should be taken with meals, specifically with the first meal of the day. Take this tablet at the same time each day to achieve optimal therapeutic benefit. Before using the Amaryl M 2mg tablet, inform the doctor if you are pregnant, planning a pregnancy, or breastfeeding, and provide a detailed medical history.

An individual with uncontrolled diabetes is at greater risk of various health complications such as eye, kidney, and nerve problems, as well as heart diseases and stroke.

Dosage

Overdose

• An overdose of Amaryl M Tablet may lead to hypoglycemia (low blood sugar) and lactic acidosis (Excessive lactic acid build-up).
• This results in headache, nausea, vomiting, sleep disturbances, restlessness, impaired alertness and reactions, depression, confusion, dizziness, etc.
• If you experience these symptoms, take glucose or juice or sugar-containing products (sugar candy) and contact the doctor or visit the nearest hospital as you may require close monitoring for the next few hours.

Missed a Dose

• A missed dose may lead to high blood sugar levels, which includes symptoms like feeling thirsty, excessive urination, loss of appetite, dry mouth, the fruity smell from breath, etc.
• If you have missed taking a dose of the Amaryl M Tablet, take it as soon as you remember.
• If it's time for the next dose, skip the missed dose and continue with the regular dose schedule.
• Avoid taking a double dose to compensate for the missed one.

Mode of Action

How Does It Work?

• Amaryl M Tablet controls blood sugar to a greater extent than metformin or glimepiride alone.
• Glimepiride lowers the blood sugar level and increases the release of insulin from the pancreas.
• Insulin passes sugar (glucose) from the blood into the cells.
• Metformin decreases the absorption in the intestine and the production of sugar in the liver.
• Both of these components increases the insulin sensitivity of the body (which allows the cells of the body to use blood glucose more effectively, reducing blood sugar).

Directions for Use

Take as directed by the doctor. Swallow as a whole with a glass of water, with meals. Do not cut, break or chew the medicine. Take at a fixed time every day for optimal results. Avoid consuming more than prescribed by the doctor.

Precautions and Warnings

Pregnancy

Can I take Amaryl M Tablet during pregnancy?

Avoid during pregnancy as it may cause harm to the unborn baby. Inform the doctor if you are planning a pregnancy, he might suggest other alternatives.

Breast Feeding

Can I take a Amaryl M Tablet while breastfeeding?

There is little safety information available, avoid while breastfeeding. The doctor may prefer an alternate medicine while nursing a newborn /premature infant.

Driving

Can I drive after consuming the Amaryl M Tablet?

• Amaryl M Tablet causes low blood sugar levels which leads to drowsiness, unconsciousness or confusion. It is dangerous while driving.
• Consult the doctor whether you can drive a car if you have frequent episodes of hypoglycemia.
• Keep a juice or chocolate in the car while driving, in case you start feeling the symptoms of hypoglycemia, have the juice or chocolate.
• Avoid artificial sweeteners.

Alcohol

Can I consume alcohol while taking Amaryl M Tablet?

• Avoid alcohol during treatment with Amaryl M Tablet.
• Alcohol alters the way medicine works. Avoid consuming consume alcohol on an empty stomach. Alcohol increases the risk of low blood sugar.
• Excessive consumption of alcohol while taking the medicine cause an increased risk of lactic acidosis.

Other General Warnings

Talk to your doctor if

• You suffer from hunger, headache, nausea, vomiting, sleepiness, restlessness, aggression, reduced alertness, confusion, shakiness or dizziness. These could be signs of low blood sugar. If you have any of these, have sugar or sweet juice. Inform the doctor as you may need a change in the medicine's dose.
• You suffer from pins-and-needles sensation, numbness and weakness.
• You are undergoing a diagnostic imaging test that involves the injection of iodine.
• You suffer from dehydration due to diarrhoea, vomiting or limited fluid intake.
• You have suffered through trauma.
• You are undergoing surgery shortly.
• You have or had thyroid, kidney and liver disease.
• You skip meals or have irregular mealtimes.
• You suffer from weight gain (specific diet restriction may be suggested).

Contraindications

• If you are allergic to metformin, glimepiride or other ingredients of the Amaryl M Tablet.
• If you are pregnant or are breastfeeding.
• If you have kidney or liver failure.
• If you have metabolic acidosis (too much acid in the body fluids) like lactic acidosis, diabetic ketoacidosis or diabetic pre-coma.
• If you suffer from dehydration, severe infections, shock and injections containing iodine.
• If you have or had heart or lung failure, the incidence of heart attack and shock.
• If you are an alcoholic.

Side effects

• Headache
• Nausea
• Vomiting
• Nausea
• Sleepiness
• Low blood sugar level

Interactions

Interactions with other medicines

• Inform the physician about any medicines, supplements, or herbal products you take or may consider taking to avoid potential interactions.
• You may experience symptoms of low blood sugar if you are taking other diabetes medications such as insulin, pioglitazone, high blood pressure medications (ACE inhibitors like captopril), steroids, chloramphenicol, fenfluramine, cholesterol-lowering medications (fibrates), depression treatments (fluoxetine), or blood clotting medications like coumarins, cyclophosphamide, miconazole, probenecid, and antibiotics like clarithromycin, doxycycline, ofloxacin, among others.
• You may also experience symptoms of high blood sugar if you are taking oral contraceptives, acetazolamide, diuretics, phenytoin, rifampicin, constipation treatments, and medications for thyroid disorders.
• Medications such as anti-allergics (ranitidine), clonidine, reserpine, and those used to treat high blood pressure (like atenolol) can alter the efficacy of the medication and may inhibit the body's response to low blood sugar, leading to dangerously low levels of blood sugar.
• Medications like diclofenac, ibuprofen, diuretics, and enalapril may impact kidney function if taken alongside the medication.
• Medications used to treat thyroid disorders can influence how the medication functions.

Interactions with food items

It is recommended to take Amaryl M 2 mg with food to help reduce the risk of gastrointestinal side effects and to enhance the medication’s effectiveness.

Storage and disposal

• Store at room temperature in a dry place.
• Protect it from direct sunlight and moisture.
• Keep it away from children and pets.

Frequently Asked Questions (FAQs)

What should I avoid being a diabetic patient?

• Avoid shopping when you are hungry. You end up buying oily and fried food.
• Avoid overeating.
• Avoid using maida, white bread, potato, noodles, corn flakes, poori, biryani, naan, fried rice, etc.
• Stop having daals with ghee, deep-fried pulses.
• Avoid using cream soups, carrot juice, deep-fried vegetables, vegetable curries with excess oil.

For how long do I need to take Amaryl M?

You have to take this medicine for as long as a doctor has prescribed you. Do not stop the treatment mid-way even if you feel better, without consulting a doctor.