Anobliss Cream

Anobliss cream is a medication used to treat conditions such as anal fissures and haemorrhoids. Its action is based on a combination of two active ingredients: lidocaine and nifedipine. Lidocaine functions as a local anaesthetic, working on the nerves to block the conduction of pain sensations for a short duration, thereby helping to reduce pain.

Nifedipine, a calcium channel blocker, works by relaxing the blood vessels and muscles around the anal canal. This relaxation is crucial because the contraction of the anal sphincter and muscle spasm around the fissure often impedes the healing process. The dual mechanism of Anobliss cream promotes better healing of the anal fissure by addressing both pain and muscle spasm.

By relaxing the muscles, it allows blood to flow more easily, aiding the healing process, and by numbing the area, it provides relief from the pain and inflammation associated with these conditions. You should apply this medicine to the affected area as directed by your doctor, making sure to wash your hands thoroughly before and after application, and ideally using gloves. While this medicine is for external use and therefore less likely to interact with other medicines, you should still consult your doctor if you are taking any other medicines for other health conditions.

It is important to continue using the cream as prescribed, even if you begin to feel better, as complete healing can take time. Avoid using any other medicine on the affected area simultaneously with Anobliss cream. Do not use Anobliss cream if you have a history of allergy to any of its contents.

It is also contraindicated if you have certain medical conditions like anaemia, low blood pressure, dehydration, heart-related disorders, or if you feel an increased pressure in the brain. If you are pregnant or breastfeeding, it is advised to consult your doctor before use. If you experience any adverse effects like rectal bleeding, pain, burning sensation, or blistering, you should report this to your doctor immediately.

Anorelief cream and Fidonal cream also have lidocaine and nifedipine as their active ingredient.

Dosage

Overdose

As Anobliss cream is meant for external application cases of overdose are unlikely. However, upon accidental ingestion contact your doctor immediately or visit the nearest hospital. If you have applied extra quantities of it wipe out the excess of the medicine with tissue or cotton.

Missed a Dose

If you have missed applying Anobliss cream, apply it as soon as possible. Do not over apply this medicine just to compensate for the missed dose.

Mode of Action

How Does It Work?

• Contraction of the anal sphincter and muscle spasm around the fissure prevents the healing process of the anal fissure. This muscle contraction is dependent on calcium.
• Nifedipine is a calcium channel blocker that works by blocking this calcium from entering the blood vessels, thus relaxing blood vessels so that blood can flow more easily and relaxing the muscles around the anal canal.
• Lidocaine is a local anaesthetic. It acts on nerves and blocks the conduction of pain sensations for a short duration of time. Thereby helping in reducing pain sensation.
• A combination of this medicine helps in better healing of the anal fissure.

Directions for Use

• Wash your hands thoroughly. Wear gloves while using Anobliss cream to reduce the possibility of side effects.
• Lie down on your left side in a comfortable position with your left leg flat and your right leg bent with your knee in the air.
• Put a required quantity on your finger and spread the ointment around the anus and just inside the rectum.
• Remove gloves and wash hands.
• Follow the doctor's advice.
• Use this medicine for the duration your doctor has advised.
• It may take several weeks to heal the fissure, so your doctor may advise frequent follow-ups to check the clinical condition.
• Your doctor may advise adding fibre to your diet and may ask you to increase your water intake and take relaxing baths or sitz baths.

Precautions and Warnings

Pregnancy

Can I use Anobliss cream during pregnancy?

It is advised to consult your doctor before using Anobliss cream, especially during the first trimester.

Breast Feeding

Can I use Anobliss cream while breastfeeding?

It is advised to consult your doctor before applying Anobliss cream while breastfeeding. In case you have been prescribed this medicine, avoid using large quantity for the long term.

Driving

Can I drive if I have applied Anobliss cream?

Anobliss cream does not influence your driving ability. However, it is advised to avoid activities requiring long sitting as it may increase the pain due to rectal fissure.

Alcohol

Can I consume alcohol during the treatment with Anobliss cream?

There is no known interaction with alcohol along with this medicine. Consult your doctor if you drink too often.

Other General Warnings

Talk to your doctor if

• You feel that symptoms are getting worse instead of getting better.
• You do not feel any improvement within a week.
• If you feel any adverse effects like rectal bleeding, pain, burning sensation, blistering etc. report to your doctor immediately.
• You should discuss your complete medical history and ongoing medications with your doctor before using this medicine.
• You are pregnant or breastfeeding.
• You should try to avoid constipation, as it may exaggerate the symptoms.

Contraindications

• If you have a history of allergy to Anobliss cream or any of the content of the medicine.
• If you have certain medical conditions like anaemia, low blood pressure, dehydration, heart-related disorders etc.
• If you feel an increased pressure in the brain.
• If you are pregnant or breastfeeding.

Side effects

• Allergy at the application site
• Irritation on the rectal area

Interactions

Interactions with other medicines

• Since this medicine is to be used externally on the skin it is less likely to interact with other medicines. However, you should always consult your doctor if you are taking other medicines for treating other health conditions.
• Avoid simultaneous application of any other medicine on the affected area after applying Anobliss cream.

Interactions with food items

Anobliss cream is for external use only.

Storage and disposal

• Anobliss cream should be stored below 25°C.
• Keep it out of the sight and reach of children.
• Do not use it after the expiry date.
• Do not throw away any medicines via wastewater or household waste.

Frequently Asked Questions (FAQs)

Can I take other medicines with Anobliss cream?

Since this medicine is to be used externally on the skin it is less likely to interact with other medicines. However, you should always consult your doctor if you are taking other medicines for treating other health conditions like cough cold medicines, medicines for migraine, medicine for high blood pressure and medicine to dissolve a blood clot.

Does Anobliss heal fissure?

Yes, Anobliss cream heals the fissure. This cream decreases the pain and inflammation caused due to anal fissure.

What should I do if I miss a dose of Anobliss cream?

If you have missed applying Anobliss cream, apply it as soon as possible. Do not overapply this medicine just to compensate for the missed dose.

How should I store Anobliss cream?

Anobliss cream should be stored at temperatures below 25°C. Keep it out of reach and sight of children. Do not use it past the expiration date.