Bavencio 200mg Vial Of 10ml Solution For Infusion

Bavencio injection is a cancer medication for use in adults and adolescents aged 12 years and older. It is used to treat metastatic Merkel cell carcinoma (a rare type of skin cancer). In patients with urothelial carcinoma (bladder cancer), it prevents the cancer from returning after initial treatment with chemotherapy, as well as in cases where the cancer has progressed during or after chemotherapy or within a year of treatment before surgery or after surgery.

Dosage

Overdose

This medicine is administered by healthcare professionals, so it is unlikely that you will be given too much medicine. If you think you have been given too much medicine, tell your doctor. You may experience side effects if you have been injected with too much medicine.

Missed a Dose

This medicine is given by a healthcare professional, so it is unlikely that you will miss a dose. If a dose is missed, you can talk to your doctor. However, if it is nearly time for the next dose, skip the missed dose. Do not take a double dose to make up for a forgotten dose.

Mode of Action

How Does It Work?

Avelumab is an immunotherapy medication that helps the body's immune system fight cancer. It works by blocking certain proteins on cancer cells and immune cells, allowing the immune system to recognize and attack the cancer.

Directions for Use

This medicine will be given to you by your doctor or nurse. Self-administration is not advised.

Precautions and Warnings

Pregnancy

Can I take Bavencio solution for infusion during pregnancy?

Bavencio solution for infusion should be avoided in pregnancy and during treatment with this injection, and after 1 months after treatment has ended, it is advised to use an effective method of contraception.

Breast Feeding

Can I take Bavencio solution for infusion while breastfeeding?

It is uncertain if avelumab is excreted in human milk, and since antibodies and other medications can pass into breast milk, potential risks to infants should be considered. A careful decision should weigh the benefits of breastfeeding for the child against the advantages of avelumab treatment for the mother.

Driving

Can I drive if I have taken Bavencio solution for infusion?

Exercise caution when driving or operating machinery until you are sure Bavencio doesn't affect you.

Alcohol

Can I consume alcohol with Bavencio solution for infusion?

Alcohol is not known to interact with this medicine. However, if you consume alcohol too often, discuss it with your doctor.

Other General Warnings

Talk to your doctor if

• You have kidney disease or have had a kidney transplant.
• You have liver disease or abnormal liver function tests.
• You have a history of autoimmune diseases, such as lupus, rheumatoid arthritis, or inflammatory bowel disease.
• You are taking medications that suppress your immune system.
• You have active or prior CNS metastasis (cancer that has spread to the brain or spinal cord).
• You are pregnant, planning to become pregnant, or breastfeeding.
• You have thyroid problems or a history of thyroid disorders.
• You have diabetes or a history of endocrine disorders.
• You have had infusion-related reactions to other medications.
• You are on a sodium-restricted diet, as the infusion diluents may contain sodium.
• You have had prior myocarditis, pancreatitis, or other severe immune-mediated conditions.
• You are taking other medications, including over-the-counter drugs, vitamins, or herbal supplements.
• You experience new or worsening symptoms such as shortness of breath, chest pain, abdominal pain, jaundice, severe fatigue, or unusual swelling.
• You are scheduled for or recovering from an organ transplant.
• You have a history of neurological conditions like myasthenia gravis or Guillain-Barré syndrome.

Contraindications

If you have any allergy to avelumab or any other ingredient in this medicine.

Side effects

• Anemia
• Cough
• Dyspnea (shortness of breath)
• Nausea
• Diarrhea
• Constipation
• Vomiting
• Abdominal pain
• Fatigue
• Pyrexia (fever)
• Peripheral oedema (swelling in the extremities)
• Infusion-related reaction
• Weight loss

Storage and disposal

Store Bavencio solution for infusion in the refrigerator between (2°C to 8°C) in its original carton.