Bevatas 400mg Vial Of 16ml Solution For Infusion

Bevatas 400 injection is an anticancer medicine that is used to treat various types of cancer in adults. Bevatas 400 contains bevacizumab as the active substance that works by preventing the growth of new blood vessels that feed cancer cells. This injection will be given to you by a doctor or nurse.

Do not self-inject this medicine. Bevatas 400 must not be used by pregnant women. Women who are capable of becoming pregnant should use effective birth control during treatment and up to 6 months after treatment with Bevatas 400 injection.

Bevatas 400 is not to be used in children under 18 years of age.

Dosage

Overdose

The symptom of an overdose of Bevatas 400 injection is migraine. However, Bevatas 400 injection will be given to you by a doctor or nurse and hence, the chances of an overdose are unlikely.

Missed a Dose

It is unlikely that a dose of this injection will be missed if you are monitored in a healthcare setup. However, if you have missed taking a dose of the injection, inform the doctor or nurse immediately.

Mode of Action

How Does It Work?

Bevatas 400 works by stopping the action of a protein called vascular endothelial growth factor (VEGF) in the body responsible for making the blood vessels grow. As a result, the cancer cells are unable to produce their own blood supply and are starved of oxygen and nutrients, which slows down the growth of cancer.

Directions for Use

• Bevatas 400 will be given in the hospital by your doctor or nurse.
• Do not self-inject this medicine. Follow any aftercare instructions given by the doctor or nurse.

Precautions and Warnings

Pregnancy

Can I take Bevatas 400 injection during pregnancy?

Limited information is available regarding the use of Bevatas 400 injection in pregnancy. However, to avoid any risks to the developing baby, Bevatas 400 injection is contraindicated in pregnancy.

Breast Feeding

Can I take Bevatas 400 injection while breastfeeding?

There is no information available if Bevatas 400 injection passes into the human breastmilk. However, Bevatas 400 should not be used by breastfeeding women. Also, women should not breastfeed for at least 6 months after the last dose of Bevatas 400 injection.

Driving

Can I drive if I have taken Bevatas 400 injection?

Bevatas 400 injection has almost no effect on the driving ability. However, if you experience symptoms like sleepiness and dizziness, which may interfere with your driving ability, it is suggested that you do not drive.

Alcohol

Can I consume alcohol with Bevatas 400 injection?

There is limited information on the interaction of Bevatas 400 injection with alcohol. Please discuss with your doctor regarding the consumption of alcohol with Bevatas 400 injection.

Other General Warnings

Talk to your doctor if

• You have any condition that causes inflammation of the abdomen, like stomach ulcer, diverticulitis.
• You have cervical cancer.
• You recently had or have surgery scheduled soon, including dental surgery.
• You have problems with wound healing or have an unhealed wound after surgery.
• You have high blood pressure, diabetes, blood clots or bleeding problems.
• You have infections that occur frequently.
• You have or had pain in the mouth, teeth, jaw, swelling or sores inside the mouth, numbness or a feeling of heaviness in the jaw or loose tooth.
• You have a weak blood vessel or a tear in the blood vessel.
• You have cancer of the brain or have ever coughed or spitted blood.
• You are above 65 years of age.
• You have heart disease, received X-ray therapy to your chest or have used medicines called anthracyclines (doxorubicin).
• You have previously experienced symptoms like dizziness, swelling or skin rashes, after injection.
• You develop symptoms like headache, changes in vision, after taking this medicine.

Contraindications

• If you are allergic to bevacizumab or any other ingredient of Bevatas 400 injection.
• If you are allergic to any other recombinant human or humanized antibodies. If you are not sure what these medicines are, please confirm with your doctor.
• If you are pregnant.

Side effects

• Nausea
• Vomiting
• Weakness
• Diarrhoea
• Stomach pain

Interactions

Interactions with other medicines

• Some medicines can affect the way Bevatas 400 injection works or Bevatas 400 injection itself can reduce the effectiveness of other medicines taken at the same time.
• Tell your doctor about all medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.
• Bevatas 400 used along with sunitinib malate may cause a type of anaemia called microangiopathic haemolytic anaemia (MAHA).
• Particular care should be taken if you are taking platinum-based cancer medicines (cisplatin) or taxane-based cancer medicines (paclitaxel).

Storage and disposal

• Store in a refrigerator at 2 - 8°C.
• Do not freeze.
• Keep out of reach of children and pets.

Frequently Asked Questions (FAQs)

Can I take Bevatas 400 injection if I am pregnant?

No, Bevatas 400 injection should not be used during pregnancy. Also, women who are capable of becoming pregnant should use effective birth control during treatment and up to 6 months after treatment with Bevatas 400 injection.

What kind of cancer is Bevatas 400 injection used for?

Bevatas 400 injection is a cancer medicine that is used to treat cancer of the large intestine or rectum, non-small cell lung cancer, kidney cancer, ovarian cancer, fallopian tube cancer, peritoneal cancer and cervical cancer.

How will Bevatas 400 be given to me?

• Bevatas 400 injection will be given as a drip into your veins (intravenous infusion). A doctor or nurse will give you this injection.

Is Bevatas 400 a form of chemotherapy?

No, Bevatas 400 is not a form of chemotherapy. It is a cancer-starving medicine that prevents the growth of new blood vessels that feed cancer.