Cardace Am 5/10mg Strip Of 10 Tablets

Cardace Am Tablet is an antihypertensive medication. It contains a combination of ramipril and amlodipine as active substances. Cardace Am Tablet is used in the treatment of high blood pressure in adults.

Take Cardace Am Tablet in the exact dose and duration as prescribed by your doctor. Do not stop taking this medicine on your own. Before starting Cardace Am Tablet, inform your doctor if you are pregnant/breastfeeding and about your complete medical history.

Dosage

Overdose

If you think you have taken too much of Cardace Am Tablet, contact your doctor immediately or visit the nearest hospital.

Missed a Dose

If you missed any dose of Cardace Am Tablet, take it as soon as you remember. If it's time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

Mode of Action

How Does It Work?

• Cardace Am Tablet contains a combination of ramipril and amlodipine as active substances.
• Ramipril is an ACE inhibitor (angiotensin converting enzyme). ACE is responsible for the constriction of the blood vessels and the increase in blood pressure. Blocking the action of ACE by ramipril helps to lower blood pressure.
• Amlodipine is a calcium channel blocker that stops calcium from moving into the blood vessel wall. This prevents the blood vessels from tightening and increasing blood pressure.

Directions for Use

• Take Cardace Am Tablet as a whole with sufficient water.
• Always take this medicine exactly as prescribed by your doctor.
• Do not cut, break, or chew the medicine.
• Do not consume more than the prescribed dose.
• Do not discontinue the medicine on your own without consulting your doctor.

Precautions and Warnings

Pregnancy

Can I take Cardace Am 5/10mg Strip Of 10 Tablets during pregnancy?

Limited information is available on the effect of Cardace Am Tablet in human pregnancy. Hence, this medicine should not be used in pregnancy. Cardace Am Tablet is contraindicated for use in the last 6 months of pregnancy.

Breast Feeding

Can I take Cardace Am 5/10mg Strip Of 10 Tablets while breastfeeding?

Cardace Am Tablet may pass into the human breast milk. This medicine should not be used in breastfeeding women unless recommended by the doctor after assessing the need and the risk.

Driving

Can I drive if I have consumed Cardace Am 5/10mg Strip Of 10 Tablets?

Cardace Am Tablet may cause dizziness, tiredness, or headache. If you experience any such effects after taking this medicine that may affect your ability to drive safely, it is advised to avoid driving.

Alcohol

Can I consume alcohol with Cardace Am 5/10mg Strip Of 10 Tablets?

No, alcohol should not be consumed during treatment with Cardace Am Tablet as it may increase the risk of low blood pressure.

Other General Warnings

Talk to your doctor if

• If you are pregnant.
• If you have severe high blood pressure.
• If you have heart failure or kidney disorder.
• If you have a blockage in a portion of the left ventricle of the heart through which blood passes.
• If you have a narrowing of the arteries that supply blood to the kidneys.
• If you have or may develop a deficiency of fluid/salt (dehydration or low fluid volume in the body).
• If you are taking medicines called diuretics like furosemide or hydrochlorothiazide.
• If you have liver cirrhosis or fluid accumulation within your abdomen.
• If you are going to have major surgery or take anaesthesia.
• If you have diabetic nephropathy.
• If you are elderly((> 70 years).
• If you develop swelling under the skin after using this medicine.
• If you are using other medicines to treat other health conditions.
• If you have uncontrolled diabetes mellitus.
• If you are taking potassium supplements (including salt substitutes).
• If you have conditions like lupus erythematosus or scleroderma.

Contraindications

• If you are allergic to amlodipine, ramipril, other ACE inhibitors (enalapril, captopril), other dihydropyridine derivatives (felodipine, nifedipine), or any of the other ingredients of Cardace Am Tablet.
• If you are using medicines called sacubitril/valsartan for treating heart failure. If you are not sure what these medicines are, please confirm with your doctor.
• If you are taking medicines containing aliskiren, and you are diabetic and/or have kidney problems.
• If you have unstable or abnormal blood pressure, which causes insufficient blood flow to your organs.
• If you are more than three months pregnant.
• If you have a narrowing of both the arteries that provide blood flow to the kidneys or a narrowing of the artery in a single functioning kidney.
• If you have a history of angioedema (swelling underneath the skin).
• If you have severe low blood pressure.
• If you have a shock.
• If you have a blockage in a portion of the left ventricle of the heart through which blood passes.
• If you have had heart failure after a heart attack.
• If you are undergoing dialysis.

Side effects

• Headache
• Dizziness
• Dry cough
• Nausea
• Vomiting

Interactions

Interactions with other medicines

• Some medicines can affect the way Cardace Am Tablet works, or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
• Inform your doctor about all the medicines, supplements, or herbals you are currently taking or might take to avoid any possible interaction.
• The use of Cardace Am Tablet with other medicines for lowering blood pressure (angiotensin II receptor blockers like losartan and aliskiren) may cause an increased number of side effects like low blood pressure and high blood potassium levels.
• The use of this medicine with sacubitril/valsartan is contraindicated as this increases the risk of
• swelling under the skin.
• When Cardace Am Tablet is used with racecadotril (used for treating diarrhoea), vildagliptin (used for treating diabetes), or mTOR inhibitors like sirolimus (used to prevent organ rejection after transplant), it may increase the risk of swelling under the skin (angioedema).
• Medicines that may decrease blood pressure like nitrates, diuretics like furosemide, tricyclic antidepressants like amitriptyline, anaesthetics like propofol, muscle relaxants like baclofen, medicines used to treat enlarged prostate like alfuzosin, and antihypertensives like prazosin when used with this medicine may increase the risk of low blood pressure.
• Medicines that constrict the blood vessels like isoproterenol, dobutamine, dopamine, and adrenaline and non-steroidal anti-inflammatory medicines like ibuprofen may reduce the blood pressure lowering effect of Cardace Am Tablet.
• Medicines such as allopurinol (used for treating gout), immunosuppressants like tacrolimus (used to prevent organ rejection after transplant), corticosteroids (used to reduce inflammation), procainamide (used to treat abnormal/irregular heart rhythm), and medicines that slow/stop the growth of cells (cytostatics) when used together with Cardace Am Tablet may cause changes in the number of blood cells in the body.
• Lithium used for the treatment of mental disorders when used with this medicine may reduce the removal of lithium from the body.
• The use of Cardace Am Tablet with medicines used for the treatment of diabetes/insulin may increase the risk of low blood sugar.
• Caution should be exercised when this medicine is given along with medicines that can increase the blood potassium levels like potassium-sparing diuretics (spironolactone), trimethoprim/sulfamethoxazole (used to treat bacterial infections), potassium supplements, or potassium-containing salt substitutes.
• Cardace Am Tablet when used together with heparin (blood thinner), may increase the risk of high blood potassium levels.
• Particular care should be taken if you are taking medicines to treat HIV (ritonavir, indinavir), fungal infections (clotrimazole, ketoconazole), bacterial infections (erythromycin), high blood pressure and heart-related chest pain (verapamil), tuberculosis (rifampicin), depression (Hypericum perforatum), and muscle spasms (dantrolene).

Interactions with food items

The use of Cardace Am Tablet with grapefruit or grapefruit juice is not recommended as it may increase the blood pressure lowering effects of the medicine.

Storage and disposal

• Store Cardace Am Tablet below 30°C in a cool and dry place away from direct sunlight.
• Keep out of reach of children and pets.

Frequently Asked Questions (FAQs)

What is Cardace Am Tablet used for?

Cardace Am Tablet is used in the treatment of high blood pressure in adults aged 18 years or above.

How does Cardace Am Tablet work?

• Cardace Am Tablet contains a combination of ramipril and amlodipine as active substances.
• Ramipril is an ACE inhibitor (angiotensin converting enzyme). ACE is responsible for the constriction of the blood vessels and the increase in blood pressure. Blocking the action of ACE by ramipril helps to lower blood pressure.
• Amlodipine is a calcium channel blocker that stops calcium from moving into the blood vessel wall. This prevents the blood vessels from tightening and increasing blood pressure.