Cefina Sb 1gm Injection

Cefina Sb Injection is a combination antibiotic containing cefoperazone and sulbactam. This medication is prescribed for the treatment of severe bacterial infections across various anatomical sites, including the lungs, airways, urinary tract, skin, soft tissues, joints, and bones. Cefoperazone, a cephalosporin antibiotic, functions by disrupting the synthesis of the bacterial cell wall, which is essential for bacterial survival and replication.

This interference ultimately leads to the lysis and death of susceptible bacterial organisms. Sulbactam is a beta-lactamase inhibitor. Many bacteria produce beta-lactamase enzymes that can inactivate cefoperazone, rendering it ineffective.

Sulbactam's role is to inhibit these enzymes, thereby protecting cefoperazone from degradation and allowing it to exert its full antibacterial effect against a broader range of resistant bacteria. The combined action of these two agents provides an enhanced antibacterial spectrum, making it effective against a variety of pathogens.

Dosage

Overdose

Cefina Sb Injection is administered by a doctor or nurse, which minimizes the likelihood of receiving an overdose. If symptoms suggestive of an overdose are experienced shortly after administration, immediate medical attention should be sought.

Missed a Dose

The administration schedule for Cefina Sb Injection is managed by a doctor or nurse, making a missed dose unlikely. If a missed dose is suspected, the healthcare provider should be informed.

Mode of Action

How Does It Work?

Cefina Sb Injection acts by killing the bacteria responsible for infections. However, bacteria make an enzyme (beta-lactamases) that can destroy cefoperazone. Sulbactam inactivates this enzyme and hence helps cefoperazone to function optimally.

Usage Instructions

Cefina Sb Injection is administered by a doctor or nurse, typically in a hospital or clinic setting. It is given as an injection. Patients should adhere to any specific instructions provided by the healthcare professional during the administration or for post-procedure care.

Safety Information

Pregnancy

Limited information is available regarding the safety of Cefina Sb Injection during pregnancy. Pregnant individuals should consult their doctor, who will assess the benefits and risks before recommending its use.

Breastfeeding

Components of Cefina Sb Injection are known to pass into breast milk. Individuals who are breastfeeding should inform their doctor, who will advise on the appropriateness of using this medication during lactation.

Driving

Cefina Sb Injection is highly unlikely to impair the ability to drive or operate machinery.

Alcohol

Consumption of alcohol is strictly advised against while taking Cefina Sb Injection, as it can lead to adverse reactions such as flushing, sweating, headache, or rapid heartbeats. Alcohol should be avoided for at least five days following the last dose of this medicine.

General Warnings

Consult your doctor if you:

• Have a history of severe allergic reactions to antibiotics.
• Have a pre-existing liver or kidney disease.
• Are currently taking blood-thinning medications.
• Experience diarrhea during treatment or after discontinuing the treatment.
• Notice abnormal bleeding.
• Develop an allergic reaction after receiving Cefina Sb Injection.

Contraindications

If you are allergic to sulbactam, cefoperazone or any other antibiotics of the penicillin and cephalosporin class or any of the ingredients of Cefina Sb Injection.

Side effects

• Loose stools
• Nausea
• Vomiting
• Headache
• Fever
• Chills
• Allergic reactions
• Pain and tenderness at the site of Injection
• Rashes with redness of the skin

Interactions

Interactions with other medicines

• There is limited information available on the interactions of Cefina Sb Injection with other drugs. However, as this medicine contains sulbactam & cefoperazone, any interactions seen with these two components when taken alone may occur with this combination too.
• Medicines or solutions containing ethanol can cause flushing, sweating, headache and increased heartbeats.
• If you are taking an antibiotic that belongs to the aminoglycoside class, it is advisable to monitor kidney functions regularly.
• Simultaneous use of anti-gout medicines like probenecid should be used with caution.

Storage and disposal

• Store this medicine below 25°C.
• Protect it from light.
• Keep it out of the reach of children.
• Any unused portion should not be stored and should be discarded properly.

Frequently Asked Questions (FAQs)

What is the use of Cefina Sb Injection?

Cefina Sb Injection is used to treat severe infections caused by various bacterial organisms. It aids to treat infections of the lungs, airways, urinary tract, skin, soft tissues, joints and bones.

What do you mean by the inappropriate use of antibiotics?

Inappropriate use of antibiotics constitutes taking antibiotics when not needed, for wrong diseases, taking inappropriate dosage and not completing the course of antibiotic treatment as prescribed by the doctor.

How is Cefina Sb Injection given?

Cefina Sb Injection is usually given intravenously or intramuscularly under medical supervision. This medicine will only be by nurse or doctor. The route of administration is usually being decided by your doctor. Do not self-inject.