Depiglare Cream 15gm

Depiglare cream contains a combination of Fluocinolone, Hydroquinone and Tretinoin. It is used in adults to treat melasma of the face (dark and discoloured patches on the skin). Do not use this medicine to treat any other skin conditions than those prescribed by your doctor.

It is meant only for external application and should be applied exactly as recommended by your doctor. You may experience some application site reactions as side effects while on treatment with this medicine, but they normally fade away with time. However, if you feel the side effects persist or your condition worsens, you should contact your doctor immediately.

Before using this medicine, inform the doctor if you are pregnant, planning a pregnancy or breastfeeding and about your detailed medical history.

Dosage

Overdose

As Depiglare cream is meant for external application, cases of overdose are unlikely. However, upon accidental ingestion, contact your doctor immediately or visit the nearest hospital. If you have overapplied it, then wipe out the excess medicine with a tissue or cotton. Excessive use for a prolonged duration is not advisable as it can lead to hormonal issues.

Missed a Dose

If you have missed the application of Depiglare cream, then apply it as soon as possible. Do not overapply this cream to compensate for the missed application.

Mode of Action

How Does It Work?

• Depiglare cream works by the combined action of its components.
• Fluocinolone is a steroid that works by blocking the production of certain chemical substances in the body (prostaglandins) that cause itching, swelling, and redness.
• Hydroquinone inhibits an enzyme known as tyrosinase, which is responsible for the production of a pigment called melanin. Melanin is responsible for skin pigmentation and melasma.
• Tretinoin is a metabolite of Vitamin A and is keratolytic. It is responsible for the elimination of melanin that has been formed. It also has anti-inflammatory properties.

Directions for Use

• Depiglare cream is meant for external use only.
• Use it as directed by your doctor or pharmacist.
• Read the instructions on the label or leaflet before use.
• Clean and dry the application area.
• Wash your hands before and after using Depiglare cream.
• Apply a thin layer of this medicine on a healthy skin surface free from cuts and wounds.
• In case your eyes come in contact with this medicine, rinse your eyes with clean water immediately.

Precautions and Warnings

Pregnancy

Can I apply Depiglare cream during pregnancy?

Depiglare cream should only be used if prescribed by your doctor, as there is limited safety information available. In case you have been prescribed this medicine, avoid using it on larger skin areas for a prolonged duration.

Breast Feeding

Can I apply Depiglare cream while breastfeeding?

Depiglare cream should be used while breastfeeding only if prescribed by the doctor, as there is limited safety information available. However, caution should be exercised while using this medicine, and you should avoid using it on the breast or areas near the breast or any large area of the body for a prolonged duration.

Driving

Can I drive if I have applied Depiglare cream?

Depiglare cream is a topical preparation and may not affect the driving ability or ability to handle machinery.

Alcohol

Can I consume alcohol if I have applied Depiglare cream?

Although there is no known interaction with alcohol and Depiglare cream, it is essential to consult your physician if you have a habit of regular drinking.

Other General Warnings

Talk to your doctor if

• You develop an allergic reaction or an infection after using Depiglare cream. Immediately contact your doctor.
• You are applying the medicine on a larger skin area, broken skin or under skin folds.
• You have any type of skin infection.
• You do not notice any improvement in your condition while on treatment.
• You notice a blue-black darkening on your skin, immediately contact your doctor.
• You must avoid being in the sunlight for too long.
• You are pregnant or breastfeeding.
• You should avoid getting any medicine into your eyes, nose, mouth, open wounds, armpits, private parts. In case of such an exposure, you should wash the affected part thoroughly with water.
• Depiglare cream should not be used to treat any other condition than that prescribed by the doctor.
• A prolonged application may lead to side effects such as Cushing's syndrome (weight gain, fatty deposits under the skin, moon face, purple patches on the skin), increased sugar levels in the blood and urine.

Contraindications

• If you are allergic to Fluocinolone, Tretinoin and Hydroquinone or any other ingredients of Depiglare cream.
• If you have skin conditions such as eczema (infected skin due to allergy), rosacea (small red pustules on the face), rashes around the mouth (perioral dermatitis) or damaged skin anywhere in the body.
• If you have a skin tumour or a family history of skin tumours.
• If you have a viral or fungal skin infection, any skin ulcers, or tuberculosis.
• If you need to be exposed to the sun for a prolonged period, using sunscreen lotion is advisable.

Side effects

• Burning sensation
• Irritation
• Redness
• Itching

Interactions

Interactions with other medicines

Depiglare cream is applied externally on the skin; thus, it is less likely to interact with other medicines taken orally. However, it may interact with other topically applied medicines. You should always consult your doctor if you are taking other topical medicines for treating other health conditions.

Interactions with food items

Depiglare cream is for external use only.

Storage and disposal

• Store Depiglare cream in the original container in a clean and dry place, protected from moisture, sunlight and heat.
• Keep the medicine away from children and pets.
• Do not freeze it.

Frequently Asked Questions (FAQs)

What is the use of Depiglare cream?

Depiglare cream is used in adults for the treatment of facial melasma.

How to use Depiglare cream?

You should use Depiglare cream as instructed by the doctor. Read the instructions on the label or leaflet before use. Wash your hands before and after using this medicine unless your hands are the area to be treated. Clean the affected area and apply a small amount of the medicine.

Can Depiglare cream also be used in children?

No, Depiglare cream is not recommended for use in children and adolescents as there is limited safety data available.

What should I do if my eyes come in contact with Depiglare cream?

If you get any medicine in your eyes, rinse with water thoroughly, and keep your eyes open when you rinse. And contact your doctor.