Diphase Sp Strip Of 10 Tablets

Diphase Sp Tablet belongs to the non-steroidal anti-inflammatory medicine class of medications (NSAID). It is a diclofenac, paracetamol, and serratiopeptidase fixed-dose combination. Diphase Sp Tablets are used to relieve pain and inflammation caused by a bone or soft tissue injury, as well as to relieve postoperative inflammation, oedema (swollen tissue filled with fluid), and pain.

Diclofenac works by inhibiting the function of cyclo-oxygenase (COX), an enzyme that produces pain and swelling in wounded or damaged tissue. Diclofenac's pain-relieving effect is enhanced by paracetamol, which serves as a mild analgesic (pain reliever) and antipyretic (fever reducer). Serratiopeptidase is an enzyme that aids in the breakdown of a protein called fibrin that forms as a by-product of clotted blood at the injury site.

As a result, the fluids surrounding the injury thin out, allowing fluid drainage easier in the swollen tissue. To avoid an upset stomach, take Diphase Sp Tablet with food. To relieve stomach irritation, your doctor may prescribe antacids in addition to this medication.

The majority of negative effects of Diphase Sp Tablets do not require medical treatment and fade away over time. Nausea, vomiting, indigestion, and stomach discomfort are common adverse effects. Consult your doctor if the negative effects do not go away.

Dosage

Overdose

An overdose of Diphase Sp Tablets can initiate symptoms like diarrhoea, dizziness, drowsiness, headache, nausea and vomiting (sometimes with blood), blurred vision (common), numbness and tingling, stomach pain (with possible bleeding in the stomach and intestines), oedema (swelling in the body or legs), and wheezing. Please contact your nearest medical facility in case of emergency. Treatment of Diphase Sp Tablets overdose includes a combination of medicines and administration of fluids through a vein. Your doctor may advise treatment with activated charcoal and laxatives.

Missed a Dose

If you have missed a dose of Diphase Sp Tablet, take it as soon as you can. However, if the next scheduled dose of Diphase Sp Tablet is approaching, continue with the regular schedule and skip the missed dose.

Mode of Action

How Does It Work?

Diphase Sp Tablet is a pain reliever that combines three medications: diclofenac, paracetamol, and serratiopeptidase. Diclofenac acts by inhibiting the chemical action of cyclo-oxygenase (COX), an enzyme that creates prostaglandins (pain and inflammation mediators), which are responsible for the sensation of pain and inflammation at the sites of injury and damage. Paracetamol inhibits the production of a natural substance called prostaglandin, which causes pain, inflammation, and fever. In cases of fever, paracetamol has an antipyretic action and can lower body temperature. Paracetamol acts by resetting the brain's temperature-regulating centre, lowering fever temperature. Serratiopeptidase helps to reduce pain and inflammation by preventing the release of chemical messengers that produce pain and fever. It reduces arthritic pain and inflammation by increasing antibiotic penetration and microcirculation at the injury site. Serratiopeptidase helps break down the insoluble protein (fibrin) by-product of blood clotting into smaller pieces. It also promotes thinning of the body's fluids as a result of damage, enabling fluid outflow easier in swollen tissue. These medicines work together to relieve pain and inflammation while also speeding up the healing process.

Directions for Use

• Based on your medical condition and reaction to therapy, your doctor will determine how long you should take the Diphase Sp Tablets. Take Diphase Sp Tablet as directed by the doctor.
• Swallow Diphase Sp Tablet as a whole with a glass of water. Do not crush, chew, or break it.
• Take Diphase Sp Tablet with food to avoid an upset stomach.
• For optimal pharmacological effects, take Diphase Sp Tablet at the same time every day.
• Do not alter the dose of Diphase Sp Tablet without consulting with the doctor.

Precautions and Warnings

Pregnancy

Can I take Diphase Sp Tablets during pregnancy?

Diphase Sp Tablets should not be used during pregnancy. Taking this medicine while pregnant can cause cardiac problems in the foetus, cause birth delays, and raise the chance of bleeding. Before taking this medication, talk to your doctor.

Breast Feeding

Can I take Diphase Sp Tablets while breastfeeding?

Diphase Sp Tablets should not be taken if you are breastfeeding since traces of the medicine can enter into breast milk and harm your baby. Before using any medication, talk to your doctor about the advantages and hazards.

Driving

Can I drive if I have taken Diphase Sp Tablets?

Diphase Sp Tablets might induce headaches, blurred vision, dizziness, or drowsiness. This may impair your driving skills.

Alcohol

Can I consume alcohol with the Diphase Sp Tablets?

No, because drinking alcohol while using Diphase Sp Tablets can reduce your blood pressure and cause dizziness, headaches, and heart rate abnormalities.

Other General Warnings

Talk to your doctor if

• You have a planned surgery. Diphase Sp Tablets should be stopped at least 10-14 days before a scheduled operation to reduce the risk of bleeding during and/or after the procedure.
• You suffer from chronic malnutrition. Diphase Sp Tablets toxicity can be exacerbated by malnutrition and fasting. Dose adjustments should be made in accordance with body weight.
• You experience symptoms of an allergic response, such as a skin rash, itching/swelling (especially in your face/tongue/throat), acute dizziness, difficulty breathing, etc.
• Diphase Sp Tablets should not be used for more than 4 weeks due to the lack of safety and efficacy for long-term use.

Contraindications

• If you are allergic to the active or inactive components of Diphase Sp Tablets.
• If you have a serious kidney ailment. Long-term usage of high-dose pain relievers can harm normal renal function.
• If you have a liver condition. When you take Diphase Sp Tablets for a long time or in excessive quantities, it can cause liver impairment.
• If you have an active peptic ulcer. Diphase Sp Tablet is a non-steroidal anti-inflammatory medicine that, if taken for a long time, can cause bleeding, stomach ulcers, or holes in the intestine. If you already have ulcers, this medicine is not suggested since it may make them worse.

Side effects

• Diarrhoea
• Excessive eating
• Severe allergy
• Nausea or Vomiting
• Bloody and cloudy urine
• Tiredness and weakness
• Abdominal pain
• Constipation
• Skin rash
• Unusual bleeding or bruising
• Mouth sores
• Indigestion
• Heartburn
• Loss of appetite

Interactions

Interactions with other medicines

• To avoid side effects associated with medicine interaction, it is important to inform the doctor about all medicines and health supplements you are currently taking.
• Diphase Sp Tablets may interact with the following medications, causing undesirable effects:
• Pain killers (nimesulide, aspirin): may cause an increased risk of internal bleeding
• anti-cancer (methotrexate): increased risk of nephrotoxicity (kidney damage) and diclofenac toxicity
• Lithium: concentration of lithium is increased and can cause its toxicity
• Blood thinner agents (warfarin, clopidogrel, apixaban): can cause easy bruising or bleeding
• Antiepileptic (carbamazepine): increased risk of hyponatremia (increased potassium level in the body)
• Medication used in the treatment of high blood pressure, heart failure (ramipril): increased risk of hyperkalemia (decreased sodium level in the body)
• Immunosuppressive medications (methotrexate, leflunomide): increased risk of liver damage, nephrotoxicity and diclofenac toxicity
• Hepatitis B medicine (adefovir): increased risk of nephrotoxicity

Interactions with food items

• There are no known adverse interactions of Diphase Sp Tablets with food. You can continue your regular diet unless advised otherwise by the doctor.

Storage and disposal

Store Diphase Sp Tablet in cold temperature away from direct sunlight, heat, and humidity. Do not use Diphase Sp Tablet if it is past its expiration date. Keep Diphase Sp Tablet out of the reach of children and pets at home. Dispose of unused/expired medicine as biomedical waste to avoid accidental consumption by animals and others.

Frequently Asked Questions (FAQs)

Can I take Diphase Sp Tablets for stomach pain?

No, Diphase Sp Tablets should not be used in the treatment of stomach pain without consulting a doctor. It can cause an increase in stomach acid output, which could exacerbate an undiagnosed underlying disease.

Can the use of Diphase Sp Tablets cause nausea and vomiting?

Diphase Sp Tablets might cause nausea and vomiting in some people. It can be taken with milk, food, or antacids to prevent nausea. When taking this medication, stay away from greasy or fried foods. If you're vomiting, drink plenty of water or other fluids in small, frequent amounts. Consult your doctor if you continue to vomit and notice signs of dehydration, such as dark-coloured, strong-smelling urine and infrequent urination.

Are there any specific contraindications associated with the use of Diphase Sp Tablet?

Diphase Sp Tablets should not be used by individuals who have a known allergy to any of the medicine's components or excipients or have a known allergy to other painkillers (NSAIDs). This medicine should be avoided in patients who have had stomach ulcers in the past or who have an ongoing, recurring stomach ulcer/bleeding. Patients with a history of heart failure, high blood pressure, or liver or kidney illness should avoid it.