Dubix Tablet

Dubix Tablet is a combination of two medicines, tranexamic acid and mefenamic acid. This medicine helps in relieving pain, cramps in the lower abdomen before & during menses and reduce heavy bleeding during menses. Tranexamic acid is an antifibrinolytic (promotes clotting and stops the breakdown of a clot) medicine while mefenamic acid is an anti-inflammatory medicine.

Take this medicine only when prescribed by your doctor. You should not take Dubix if you have any blood clotting disorder, history of heavy bleeding or recent bypass surgery. Do not take this medicine during pregnancy especially the last trimester.

Dosage

Overdose

The symptoms of an overdose of Dubix Tablet include nausea, vomiting, fall in blood pressure, dizziness, headache, fits or convulsions, rarely, diarrhoea, etc. In case of an overdose, contact your doctor immediately or visit the nearest hospital.

Missed a Dose

If you have missed taking any dose of this medicine take it as soon as you remember. If it's time for your next dose, then skip the missed dose and continue with your regular dose schedule. Do not take a double dose of medicine to compensate for the missed one.

Mode of Action

How Does It Work?

• Dubix Tablet works by the combined action of its two components Tranexamic acid and Mefenamic acid.
• Tranexamic acid works by improving the blood clotting by preventing or slowing down the process of break down of blood clots called fibrinolysis.
• Mefenamic acid helps in relieving the sensation of pain by inhibiting the formation of inflammatory mediators such as prostaglandin which is responsible for pain and swelling.

Directions for Use

• Dubix Tablet should be taken orally with or after food with plenty of water.
• Take this medicine as directed by your doctor.

Precautions and Warnings

Pregnancy

Can I take Dubix Tablet during pregnancy?

It is not safe to take Dubix Tablet during pregnancy as it can lead to malformations in the growing foetus. It can also delay labour and increase the risk of bleeding in the mother and foetus.

Breast Feeding

Can I take Dubix Tablet while breastfeeding?

The components of Dubix Tablet can pass into the breastmilk and may cause harm to the newborn baby. It is advised not to breastfeed during the treatment with Dubix Tablet.

Driving

Can I drive if I have consumed Dubix Tablet?

You may experience dizziness, drowsiness, fatigue and visual disturbances after taking Dubix Tablet. So, be cautious while driving or operating any machinery.

Alcohol

Can I consume alcohol with Dubix Tablet?

Alcohol consumption during the treatment can be an added risk for ulcers and gastrointestinal bleeding. Try to avoid alcohol intake along with this medicine.

Other General Warnings

Talk to your doctor if

• You have any medical history especially of bleeding in the brain (subarachnoid haemorrhage) and a history of blood clots (such as in the legs, lung, brain or eye).
• You are suffering from certain heart diseases (irregular heartbeat, heart valve problems) and blood clotting disorders.
• You have a kidney function problem or you are passing blood in the urine.
• You have epilepsy, seizures (fits) or respiratory disorders such as asthma.
• You experience visual disturbances after taking this medicine, discontinue the treatment immediately.
• You should not take Dubix Tablet if you have an irregular menstrual bleeding pattern.
• You are an elderly person, there is an increased risk of side effects such as ulcers and bleeding.
• You are taking oral contraceptives, be cautious as there is a risk of thrombosis.
• Dubix Tablets can impair your fertility. Thus, you should not take this medicine if you are trying to conceive or taking treatment of fertility.

Contraindications

• If you are allergic to mefenamic acid, tranexamic acid or any of the ingredients of Dubix Tablet.
• If you have a history of stomach or intestinal bleeding due to painkillers.
• If you have or have ever had a blood clot in your blood vessels (thrombosis).
• If you have a liver, kidney or heart function problem or any kind of health condition.
• If you have a bleeding disorder.
• If you recently had a bypass surgery of the heart.
• If you have a history of convulsions or inflammatory bowel disease.
• This medicine should not be taken in the last trimester of pregnancy.

Side effects

• Diarrhoea
• Back pain
• Headache
• Muscle pain
• Nausea
• Constipation
• Ringing in the ears
• Bloating

Interactions

Interactions with other medicines

• Sometimes Pause 500 Tablet may affect the way other medicines work and other medicines may affect how Pause Tablet works if taken at the same time. Discuss with your doctor about any other medicine, herbal preparation and supplements you are taking currently to avoid any possible interactions.
• In particular, if you are taking medicnes like blood thinners (like warfarin, heparin), antidiabetic medicines, heart-related medicines, anti-hypertensive medicines, antibiotics like gentamicin, chloramphenicol, anti-HIV medicines, etc.
• The effect of Pause 500 will be reduced if taken along with blood thinners (like warfarin, heparin) which are medicines that inhibit clot formations.
• An additive effect may be seen if the patient is taking medications that increase blood clot formation (like aprotinin).
• Oral contraceptive pills, when taken with Dubix, may promote blood clot formation which can be harmful, leading to blockage of blood vessels by abnormal clot formation. Inform your doctor if you are taking birth control pills.

Storage and disposal

• Store this medicine below 25°C.
• Store it in a cool and dry place and try to keep it in the original container.
• Keep it away from the reach of children and pets.

Frequently Asked Questions (FAQs)

Can Dubix Tablet be taken during periods?

Yes, Dubix is meant to reduce cramps and pain before and during periods as well as to control excessive bleeding during periods. However, Dubix Tablet is taken when prescribed by your doctor or gynaecologists. Do not self-medicate with this medicine without consulting a doctor.

When does the bleeding stop after taking Dubix Tablet?

Dubix Tablet does not stop bleeding but reduces the heavy menstrual flow by improving the blood clot. It usually starts showing its effects within 1-2 hours.

Can Dubix Tablet cause acidity?

Yes, Dubix Tablet may cause acidity, hence you should always take it with food and with antacids. It reduces the chance of stomach discomfort.

Is Dubix Tablet safe?

Yes, Dubix Tablet is safe if you take it at the dose and duration prescribed by your doctor. If you stop taking this Tablet once you start feeling good, the chance of bleeding might increase.

Can I take Dubix every month?

Usually, you can take Dubix as per the need. It is usually prescribed for a short duration. Take it for as long as the doctor has told you to take it. Do not exceed the prescribed duration.

How long does Dubix take to work?

Dubix usually starts working within 1-2 hours of its oral intake. However, it can vary among individuals depending on their physiology and other biological parameters.

When do you use Dubix?

Dubix Tablet is used for the treatment of menstrual cramps and pain due to heavy bleeding during menses.

What is the composition of Dubix?

The composition of Dubix consists of a combination of two medicines, tranexamic acid and mefenamic acid.