Esoga-RD Capsule

Esoga Rd Capsule contains combination of Rabeprazole and Domperidone, an anti-reflux medicine. It is used to treat Gastroesophageal reflux disease (GERD) also known as acid reflux condition. The acid from the stomach moves back up to the food pipe along with contents of the stomach characterized by heartburn, chest pain, burning, pain and regurgitation of food or sour liquid due to irritation of the stomach.

This medicine lowers the acid secretion in the stomach and prevents the outflow of contents of the stomach to the food pipe. Esoga Rd Capsule should be taken at least 30min before meals for the best result. Avoid spicy and oily food while on this medicine.

Dosage

Overdose

• Symptoms of overdose of Esoga Rd Capsule include confusion, anxiety, fits, altered consciousness, sleepiness, etc.
• If you think you have taken too much of this medicine, contact your doctor immediately or visit the nearest hospital.

Missed a Dose

• If you missed any dose of the medicine take it as soon as you remember.
• If it's time for your next dose, then skip the missed dose and continue with your regular dose schedule.
• Do not take a double dose of medicine to compensate for the missed one.

Mode of Action

How Does It Work?

• A pump called the proton pump in the stomach is responsible for the secretion of stomach acids. Rabeprazole binds to this proton pump in stomach cells, thus blocking acid secretion.
• Domperidone increases the motility of the stomach and intestines so that acid does not reflux back into the food pipe.

Directions for Use

Esoga Rd Capsule should be taken as directed by your doctor. Swallow it whole with a glass of water. Do not cut, break or chew the medicine. It should be taken preferably in the morning before food. It would be best if you took it at a fixed time for optimal results and should not consume it more than that prescribed by your doctor.

Precautions and Warnings

Pregnancy

Can I take Esoga Rd Capsule during pregnancy?

• The components of Esoga Rd Capsule might harm your unborn baby. Do not use this medicine during pregnancy, unless prescribed by your doctor after assessing the need and safety.
• Inform your doctor if you are pregnant or think you may be pregnant or planning to have a baby.

Breast Feeding

Can I take Esoga Rd Capsule while breastfeeding?

• Esoga Rd Capsule passes into breast milk in small amounts and might affect your baby.
• Consult your doctor if you are breastfeeding. After assessing the necessity and safety, your doctor might either change the medicine or ask you to stop breastfeeding or closely monitor the baby.

Driving

Can I drive if I have consumed Esoga Rd Capsule?

If you experience drowsiness and visual disturbances after taking Esoga Rd Capsule, it is advised not to drive or use machines.

Alcohol

Can I consume alcohol with Esoga Rd Capsule?

Drinking alcohol when you are taking this medicine does not affect the way it works. However, you should avoid drinking alcohol in large quantities as it is known to increase acidity and can make your acidity worse.

Other General Warnings

Talk to your doctor if

• You develop watery diarrhoea, fever after taking this medicine
• You experience black stools
• You have a stomach tumour
• You have a history of fractures or have osteoporosis or taking steroids
• You have liver and kidney disease or kidney failure
• You have heart problems and associated symptoms like palpitations, difficulty in breathing, unconsciousness
• You are on this medicine for more than three months. Your blood magnesium levels may drop. Your doctor may perform regular tests for the same
• You develop skin lesions especially in the sun-exposed area after taking this medicine
• You are taking medicines to treat HIV
• You have low levels of vitamin B12. This medicine is known to reduce the absorption of vitamin B12 after long term use. Supplements may be needed
• Taking this medicine for more than one year may increase the chances of developing bone fractures
• Esoga Rd Capsule should not be used in children below 12 years of age

Contraindications

• If you are allergic to Rabeprazole, Domperidone or any of the ingredient of Esoga Rd Capsule.
• If you are taking any medicine which might affect the contraction of the heart muscle (QT prolongation).
• If you are suffering from bleeding in the digestive system.
• If you are suffering from liver or kidney disorder.
• If you have serious heart problems like congestive heart failure, heart rhythm problems, electrolyte imbalance.
• If you have any tumour of the pituitary gland (Prolactin pituitary tumours).
• If you are pregnant or breastfeeding.

Side effects

• Nausea
• Headache
• Lack of energy
• Gas
• Skin rash
• Diarrhoea
• Dry mouth
• Stomach pain
• Sleeplessness
• Back pain
• Throat infection (Pharyngitis)
• Cough
• Vomiting
• Dizziness
• Constipation
• Breast pain and loss of sex drive

Interactions

Interactions with other medicines

• There is limited information available on the interaction of this combination with other drugs. However, as this medicine contains Omeprazole and Domperidone, any interactions seen with these two components when taken alone may occur with this combination.
• Rilpivirine should never be used with this medicine.
• Never take these medicines along with it: Disopyramide, Amiodarone, medicines for mental problems haloperidol, Citalopram, antibiotics like Erythromycin, Levofloxacin, Azithromycin, antifungals like Pentamidine, Ketoconazole and other medicines like Cisapride, Dolasetron, Mequitazine etc.
• This medicine interferes with the action of antiviral medicines like Rilpivirine, Atazanavir and Nelfinavir and antifungals like Posaconazole, Ketoconazole and Itraconazole.
• Medicine used to treat heart failure like digoxin may lead to toxicity when taken with this medicine.
• Medicines used for mental disorders like Diazepam, Phenytoin.
• If you are taking Warfarin, caution is needed as there are chances of increased bleeding.

Interactions with food items

• Esoga Rd Capsule should preferably be taken on an empty stomach
• There are no known interactions with food or beverages
• However, nicotine and caffeine (coffee, tea, chocolate and cola) can increase stomach acid or delay ulcer healing and hinder the treatment process

Storage and disposal

• Store below 25°C, protected from moisture and light
• Keep the medicine out of the reach of children

Frequently Asked Questions (FAQs)

I am suffering from a liver problem. Is Esoga Rd Capsule safe for me?

Tell your doctor if you are having any liver or kidney problem. The doctor may suggest an alternative.

I get acidity quite often, what should I do to avoid it?

• Avoid spicy and oily food.
• Reduce smoking and alcohol intake as these are known to worsen the reflux.
• Avoid carbonated drinks like cold drinks and soda as the carbon dioxide gas in these is known to worsen acid reflux.
• Reduce chocolate, mint intake.
• Some medicines are known to increase acidity and worsen the condition such as pain killers like Ibuprofen. You should avoid using these for a long duration.

I have been taking Esoga Rd Capsule for a few months now, what should I look out for?

Take Esoga Rd Capsule only for the duration as prescribed by your doctor. If there is relief in your symptoms, you may visit your doctor for a follow-up, when your doctor may reduce its dose. This medicine is known to cause fractures, low magnesium levels and vitamin B12 levels on long term use. You need to be cautious about these and keep checking your blood levels regularly and if need be your doctor may prescribe the supplements for these deficiencies.

When should I take Esoga Rd Capsule?

Esoga Rd Capsule should be taken at least 30 mins before meals.