Extacef Tazo 1125mg Dry Vial Of 1 Powder For Injection

Extacef Tazo is an antibiotic combination medication containing ceftriaxone and tazobactam. It is indicated for the treatment of severe bacterial infections. Ceftriaxone, a cephalosporin antibiotic, functions by inhibiting the synthesis of bacterial cell walls, which leads to the death of susceptible bacterial organisms.

Tazobactam is a beta-lactamase inhibitor. Its role is to protect ceftriaxone from degradation by bacterial enzymes known as beta-lactamases. By inactivating these enzymes, tazobactam extends the spectrum of activity and enhances the efficacy of ceftriaxone against various resistant bacterial strains.

This combination therapy is designed to overcome bacterial resistance mechanisms, ensuring optimal antibacterial action against a broad range of pathogens responsible for severe infections. Administration of this medication is typically performed by a healthcare professional.

Dosage

Overdose

• Your doctor or nurse will give Extacef Tazo Powder For Injection, therefore chances of an overdose are rare.
• However, if you experience nausea, vomiting, diarrhoea and stomach upset immediately after taking this Powder For Injection, inform your doctor or reach out to your nearest hospital as soon as possible.

Missed a Dose

• You will be monitored by your doctor or nurse on when Extacef Tazo Powder For Injection should be given to you.
• It is unlikely that the dose will be missed.
• However, if you think your doctor or nurse might have missed a dose, inform them.
• It is advisable not to miss any dose of antibiotics as it can fail therapy.

Mode of Action

How Does It Work?

• Ceftriaxone acts by killing the bacteria responsible for infections.
• However, bacteria make an enzyme (beta-lactamases) that can destroy ceftriaxone.
• Tazobactam inactivates this enzyme, thereby helping it to function optimally.

Usage Instructions

This medication is administered by a healthcare professional. Self-administration is not recommended.

• Follow all instructions provided by the administering clinician.

Safety Information

Pregnancy

Limited safety data is available regarding the use of this medication in pregnant women. It should only be used during pregnancy, particularly in the first trimester, if deemed essential by a doctor after a thorough assessment of potential benefits versus risks.

Breastfeeding

• Components of this medication pass into breast milk. Inform your doctor if you are breastfeeding. Your doctor will advise on its use after assessing the necessity and benefit.
• If prescribed, monitor the child closely for antibiotic-related side effects such as diarrhoea or oral fungal infections.

Driving

This medication may cause dizziness. Exercise caution or avoid driving if experiencing dizziness after administration.

Alcohol

Alcohol consumption may worsen side effects such as dizziness when combined with this medication. It is advisable to avoid alcohol if this medication has been administered.

General Warnings

Consult your doctor if:

• You have a history of allergic reactions to antibiotics.
• You develop diarrhoea after receiving this medication. Inform your doctor immediately.
• You have recently received or are scheduled to receive any calcium-containing products.
• You have severe liver or kidney disease.
• You are on a low-sodium diet.
• You have gall bladder disease.
• You have anaemia.
• You suffer from any inflammatory bowel disease (colitis).

Contraindications

• If you are allergic to ceftriaxone, tazobactam and any of the ingredients of Extacef Tazo Powder For Injection.
• If you are allergic to Cephalosporins, Penicillins, Monobactams and Carbapenems.
• If the patient is a premature baby.
• If a newborn has jaundice or is on calcium Powder For Injection treatment.
• If a newborn is suffering from increased bilirubin (liver enzyme) in the blood.

Side effects

• Diarrhoea
• Rash
• Itching and pain at the Powder For Injection site
• Headache
• Dizziness
• Nausea

Interactions

Interactions with other medicines

• Some medicines can affect the way the Extacef Tazo Powder For Injection works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
• Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.
• Extacef Tazo Powder For Injection should never be given along with Ringer's or Hartmann's solution.
• This Powder For Injection alters the action of oral contraceptives. Thus it is advisable to use alternative contraceptive measures like condoms when you are taking this medicine.
• Extacef Tazo Powder For Injection should never be given through the IV line through which calcium-containing solutions are given.

Storage and disposal

• Store Extacef Tazo Powder For Injection below 25°C protected from light.
• Keep it out of the reach of children and pets.
• Any unused portion should not be stored and should be discarded properly.

Frequently Asked Questions (FAQs)

For how long do I need to take this Extacef Tazo Powder For Injection?

You are supposed to complete the prescribed duration of antibiotics by your doctor. Otherwise, there is a possibility of reoccurrence of the infection.

Can the use of Extacef Tazo Powder For Injection cause diarrhoea?

Yes, the use of Extacef Tazo Powder For Injection can cause diarrhoea along with the desired effect, but not everyone gets them. It is an antibiotic that kills both good and bad bacteria, when good bacteria present in the intestine gets killed it can cause diarrhoea. If you are experiencing severe diarrhoea, talk to your doctor about it.

Can the Extacef Tazo Powder For Injection use to treat urinary tract infection (UTI)?

Yes, the Extacef Tazo Powder For Injection can be used to treat urinary tract infection (UTI) caused by infection-causing bacteria. Your doctor may prescribe you this medicine based on the condition of your infection and its severity.

What is the dose of Extacef Tazo Powder For Injection?

The dose and duration of the treatment with Extacef Tazo Powder For Injection will be decided by the doctor. It should be given till the time you see an improvement in your health conditions.