Glenstim Peg 6mg Pre Filled Syringe Of 0.6ml Injection

Glenstim Peg Injection is used to improve the growth of white blood cells in the body. The primary use of Glenstim Peg Injection is to prevent infections after chemotherapy for cancerous tumours. This medicine is given to patients whose immune systems cannot fight the infection because of low white blood cell count.

This injection consists of granulocyte stimulating growth factor as its main ingredients. Growth factors are groups of proteins that stimulate the growth of specific tissues in the body. The mode of action of Glenstim Peg Injection is to stimulate the bone marrow to increase the production of white blood cells and protect the body against infections.

Weakness, headache, bone pain, rash, etc., are some of the side effects of Glenstim Peg Injection. If these side effects do not subside or increase in severity, consult the doctor.

Try to follow the doctor’s directions for using the Glenstim Peg Injection. This injection should be given only by a doctor or a nurse. Do not self-administer this injection.

The patient may notice swelling, lump, bruise, or pain at the site of the injection. They will subside once you get used to the medicine in a few weeks. Regular blood tests are done to check to the number of total blood cells in the body and bone density while using this medicine.

This injection is not given to pregnant or breastfeeding women. Effective contraception is recommended to avoid pregnancy.

Dosage

Overdose

An overdose on Glenstim Peg Injection can occur if it is being used repeatedly many times or a lot of amount of injection is used at one time. In case these symptoms persist or get worse, consult your doctor for appropriate medical treatment.

Missed a Dose

Glenstim Peg Injection is given at a hospital by the doctor or healthcare professional. They will monitor the dose of Glenstim Peg Injection during the whole infusion period. It is unlikely that the dose will be missed in this situation. If you think the doctor might have missed a dose, inform them.

Mode of Action

How Does It Work?

Glenstim Peg Injection contains Granulocyte colony-stimulating factor (G-CSF). It works on the central nervous system to reduce the death of neutrophils or white blood cells. It stimulates the bone marrow to produce more white blood cells. It also causes cells from the bone marrow to become mature and active.

Directions for Use

• Glenstim Peg Injection is given to the patient in the hospital by the doctor or healthcare professional.
• Glenstim Peg Injection infusion is given intravenously (directly into the veins) or subcutaneously (into the fatty layer).
• Do not take this injection by yourself intravenously.
• For subcutaneous injections, use this injection in a clean and dry area.
• If you have any doubts about injecting yourself, ask your doctor.
• Disinfect the place where you are taking this injection.
• It should not be diluted with water.
• Follow the instructions given by the doctor during the infusion and for aftercare.
• If you have any breathing problems, rash, or swelling, inform your doctor immediately.

Precautions and Warnings

Pregnancy

Can I take the Glenstim Peg Injection during pregnancy?

It can be unsafe to use Glenstim Peg Injection in pregnant women. There are not enough studies on the safety of this medicine, and some have shown that this medicine does not cause any harm to the baby. However, use this injection only if your doctor advises it.

Breast Feeding

Can I take the Glenstim Peg Injection while breastfeeding?

There is limited data present on how Glenstim Peg Injection affects breastfeeding. Please consult your doctor before starting this injection.

Driving

Can I drive if I have taken the Glenstim Peg Injection?

It is not known if Glenstim Peg Injection influences the ability to drive or use heavy machinery. Do not drive if you notice any side effects that can affect your ability to drive.

Alcohol

Can I consume alcohol with the Glenstim Peg Injection?

There is no data available on the effects of alcohol with topical Glenstim Peg Injection

Other General Warnings

Talk to your doctor if

• You are diagnosed with HIV infection; caution should be used.
• You have a low neutrophil or white blood cell count due to viral infection.
• You are diagnosed with anaemia or a low red blood cell count.
• You have severe liver or kidney issues.
• You are using any medicines that lower neutrophil count.

Contraindications

• If you have a known hypersensitive reaction to the Granulocyte colony-stimulating factor or any other components of this injection.
• If you have a history of lung disorders such as pneumonia, acute respiratory distress syndrome (ARDS).
• If you have any severe kidney failure.
• If you are diagnosed with low blood pressure, low albumin, oedema, or anaemia. This injection can cause capillary leak syndrome, which can be life-threatening.
• If you have splenomegaly or rupture of the spleen.
• If you are diagnosed with myelodysplastic syndrome or chronic myelogenous leukaemia (types of blood cell disorders).
• If you have a severely low platelet count.
• If you are diagnosed with Aortitis, inflammation of the aorta, a major blood vessel.
• If you are diagnosed with Sickle cell anaemia (condition of red blood cells)

Side effects

• Nausea,
• Back pain,
• Pain in extremities,
• Increased white blood cell count,
• Muscle pain,
• Increased lactate dehydrogenase level in the blood,
• Low blood platelets.

Interactions

Interactions with other medicines

• Using Glenstim Peg Injection and other chemotherapy medications that suppress the growth of white blood cells is not recommended. The exact safety and efficacy of using these medicines together are not established. It is advised to maintain at least a gap of 24 hours between using these medications. Some studies have shown that the white blood count is severely affected.
• Other growth factors that increase the count of red blood cells when given along with Glenstim Peg Injection are not advisable. The exact reaction when they are used together is not established. So, use it with caution.
• Using antipsychotic medication such as lithium can increase the neutrophil count, increasing the effectiveness of Glenstim Peg Injection. The dose of the lithium should be checked before giving it with this injection.

Interactions with food items

• There is no data available on food interactions with Glenstim Peg Injection.

Storage and disposal

Store the Glenstim Peg Injection in the refrigerator at a temperate 2 to 5 degrees celsius. Do not let the medication freeze. Store them in their original container to keep them away from direct sunlight. Keep Glenstin Peg's injection away from pets and children. Dispose of the packaging carefully after use. Do not use the medicine if the package has been opened. Check the expiration date on the packaging before taking the injection. If the medicine is past the expiration date, do not use it. Dispose of unused/expired medicine as biomedical waste.

Frequently Asked Questions (FAQs)

Can Glenstim Peg Injection cause any fertility problems if I use them regularly?

There is no study that indicates that Glenstim Peg Injection can cause any problem to fertility in men or women.

How is Glenstim Peg Injection given to me?

Generally, Glenstim Peg Injection is given under the skin (subcutaneously) into the stomach, legs, or top of your arm. There might be a dull pain after the injection, but usually, it doesn't hurt much. The skin in the area can get red or itchy for some time.

What is the more effective time to get Glenstim Peg Injection?

It is better to take Glenstim Peg Injection 24 hours after taking the chemotherapy medicines for more effectiveness. Follow your doctor's advice on how and when to take it.