Istamet G IR 50/1000/1 Tablet

Istamet G Ir Tablet is a combination of glimepiride, metformin, and sitagliptin. It is used to treat diabetes. It is prescribed, along with diet and exercise, to help control blood sugar levels in adults with type 2 diabetes mellitus.

It is important to avoid using Istamet G Ir Tablet if you have respiratory failure, severe kidney disease, liver disease, heart failure, recent heart attack, severe circulatory problems, or breathing difficulties. It is crucial to consult your doctor before taking this medication. Istamet G Ir Tablet is not recommended during pregnancy or while breastfeeding, as the medication can be passed through breast milk.

It is essential to seek medical advice before starting this medication if you are pregnant or nursing. Common side effects of Istamet G Ir Tablet include low blood sugar, nausea, vomiting, diarrhoea, abdominal pain, flatulence, loss of appetite, and changes in taste. If you experience any worsening of these side effects, consult your doctor.

Dosage

Overdose

Symptoms of overdose include severe nausea or vomiting, pain in the stomach, muscle cramps, rapid breathing. If you have taken too much of this medicine then contact your doctor or reach out to the nearest hospital immediately.

Missed a Dose

If you have missed taking any dose of this medicine then take it as soon as you remember. If it's already time for the next dose then skip the missed dose and follow the regular dosing schedule.

Mode of Action

How Does It Work?

• Istamet G Ir Tablet consists of glimepiride, metformin, and sitagliptin. Glimepiride lowers blood glucose levels by stimulating the pancreas to release more insulin. Metformin reduces the amount of glucose you absorb from food and the amount of glucose produced by the liver. It also boosts the body's response to insulin, a natural hormone that regulates the amount of glucose in the blood. Sitagliptin regulates blood sugar levels by increasing the body's incretins, which cause the pancreas to release more insulin. It also tells the liver to stop producing sugar (glucose) when there is too much sugar in the blood.

Directions for Use

• Take Istamet G Ir Tablet with food as prescribed by your doctor.
• Do not stop taking Istamet G Ir Tablet on your own, without informing your doctor.

Precautions and Warnings

Pregnancy

Can I take Istamet G Ir Tablet during pregnancy?

Component of Istamet G Ir Tablet can cause harm to the unborn baby if taken during pregnancy. This medicine should not be taken by pregnant women.

Breast Feeding

Can I take Istamet G Ir Tablet while breastfeeding?

Component of Istamet G Ir Tablet can pass through breastmilk and can cause harm to the breastfed baby if taken by lactating mother. This medicine should not be taken by lactating mother.

Driving

Can I drive if I have consumed Istamet G Ir Tablet?

Istamet G Ir Tablet can cause dizziness or sleepiness. Avoid driving if you have dizziness or sleepiness after taking this medicine.

Alcohol

Can I consume alcohol with Istamet G Ir Tablet?

Consumption of alcohol along with Istamet G Ir Tablet can cause a medical condition called ' lactic acidosis' which can cause vomiting, pain in the stomach, breathing difficulty, tiredness, muscle cramps, decrease body temperature, decrease heartbeat. Avoid alcohol consumption while on this medicine.

Other General Warnings

Talk to your doctor if

• You have skin blister after taking this medicine.
• You have a fever, vomiting, loose motion, heat exposure, less fluid intake.
• You have vomiting, pain in the stomach, breathing difficulty, tiredness, muscle cramps, decrease body temperature, decrease heartbeat after taking this medicine.
• You have low blood sugar after taking other anti-diabetic medicines along with this medicine.
• You have type 1 diabetes mellitus.
• You are undergoing any surgery.
• Your doctor tells you that you have increase triglyceride level in your blood and you have gall stones.

Contraindications

• If you are allergic to sitagliptin, metformin, glimepiride or any other ingredients of Istamet G Ir Tablet.
• If you have severe kidney or liver disease.
• If your diabetes is not under control and you also have high blood sugar, nausea, vomiting, loose motions, rapid loss of weight, pain in the stomach, breathing difficulty, sleepiness etc.
• If you have dehydration or you have the presence of severe infection.
• If you have to go to do an x-ray or scan and dye is injected in your blood before doing the x-ray or scan.
• If you have a recent history of a heart attack.
• If you are a heavy alcohol drinker.
• If you are a lactating mother.

Side effects

• Nausea
• Vomiting
• Headache
• Metallic taste
• Flatulence
• Loose motion
• Constipation
• Stomach pain
• Loss of appetite

Interactions

Interactions with other medicines

• Some medicines can affect the way Istamet G Ir Tablet works, or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
• Tell your doctor about all the medicines, supplements, or herbals you are currently taking or might take to avoid any possible interaction.
• Especially if you are taking other antidiabetic medicines.

Storage and disposal

• Store Istamet G Ir Tablet at a temperature not above 30°C in a cool and dry place.
• Keep it out of the reach of children and pets.

Frequently Asked Questions (FAQs)

Why Istamet G Ir Tablet need to be taken with food?

Istamet G Ir Tablet should be taken with food to avoid stomach upset if taken on an empty stomach. Take this medicine as prescribed by your doctor.

Does Istamet G Ir Tablet cause weight gain?

No, Istamet G Ir Tablet does not increase weight. It neither increases nor decreases the weight. You should continue to exercise and follow your diet while you are on this medicine.