Jakura 5 Tablet

Jakura Tablet is used to treat an inflammatory disease called rheumatoid arthritis in adults. The active substance of this Tablet is tofacitinib. Rheumatoid arthritis is a long-term disease that mainly causes pain and swelling of your joints.

Jakura Tablet acts by reducing the discomfort, pain, and swelling of your joints and improves your capacity to perform daily tasks. Take this medicine in the same dose and duration as suggested by your doctor. It would be best if you take a Jakura Tablet at the same time every day to gain maximum benefits.

Inform your doctor if you have a severe infection, liver problems, allergy to tofacitinib, or are pregnant or breastfeeding. Do not stop taking this medicine even if you start feeling better, without consulting your doctor.

Dosage

Overdose

Symptoms of overdose of Jakura Tablet include headache, nausea, and diarrhoea. If you think you have taken too much of this medicine, contact your doctor immediately or visit the nearest hospital.

Missed a Dose

You should never miss your dose of medicines. However, if you missed any dose of the medicine, take it as soon as you remember. If it's time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

Mode of Action

How Does It Work?

Jakura Tablet works by blocking the action of a certain chemical in the body known as Janus kinase. This chemical plays an important role in the process of inflammation in rheumatoid arthritis. By blocking the action of this chemical, the Jakura Tablet helps to reduce inflammation, pain, and discomfort that occurs in rheumatoid arthritis.

Directions for Use

• Take this medicine as a whole with sufficient water.
• Always take this medicine exactly as prescribed by your doctor.
• Do not consume more than the prescribed dose.
• Do not discontinue the medicine on your own without consulting your doctor.

Precautions and Warnings

Pregnancy

Can I take Jakura Tablets during pregnancy?

Limited information is available regarding the safety of Jakura Tablets in pregnant women. As a precautionary measure, the use of Jakura Tablets during pregnancy is contraindicated. Women of childbearing potential (women before menopause who are capable of becoming pregnant) should use effective contraceptive measures while on treatment with Jakura Tablets.

Breast Feeding

Can I take Jakura Tablets while breastfeeding?

There is limited information available regarding the excretion of Jakura Tablets in human breastmilk. Thus, it is advised to avoid taking this medicine to prevent any risks to the breastfed child.

Driving

Can I drive if I have consumed Jakura Tablets?

Jakura Tablets have no influence on the ability to drive. However, if you feel that you may not be able to drive safely after taking Jakura Tablets, it is suggested that you do not drive.

Alcohol

Can I consume alcohol with Jakura Tablets?

There is limited information available regarding the interaction of alcohol with Jakura Tablets. Ask your doctor for advice on alcohol intake along with the Jakura Tablet.

Other General Warnings

Talk to your doctor if

• You think you have an infection or have symptoms of an infection such as fever, sweating, chills, muscle pain, cough, difficulty breathing, weight loss, warm or red or painful skin or sores on your body, difficulty or pain when swallowing, diarrhoea, stomach pain, burning when you urinate or urinating more often than normal, feeling very tired.
• You already are taking medicines for any kind of infection or have infections that keep coming back.
• You have any condition that increases your chance of infection (diabetes, weak immune system).
• You have or have a history of tuberculosis or have been in close contact with someone with tuberculosis.
• You have any kind of lung disease, liver disease, kidney disease, or heart disease (high blood pressure, high cholesterol).
• You have or had hepatitis B or hepatitis C (viruses that affect the liver).
• You are older than 65 years.
• You currently smoke or used to smoke in the past.
• You have any type of cancer.
• You have had diverticulitis (a type of inflammation of the large intestine) or ulcers in the stomach or intestines.
• You are planning to get vaccinated soon.

Contraindications

• If you are allergic to tofacitinib or any other ingredient of the Jakura Tablet.
• If you have tuberculosis (TB), serious infections such as sepsis, or opportunistic infections (infections that occur more frequently and more severely in people with a weak immune system).
• If you have any kind of liver disease.
• If you are pregnant, planning to become pregnant, or breastfeeding.

Side effects

• Headache
• Nausea
• Diarrhoea
• Cough
• Increase in blood pressure
• Infection and inflammation of the nose and throat

Interactions

Interactions with other medicines

• Some medicines can affect the way the Jakura Tablet works, or the Jakura Tablet itself can reduce the effectiveness of other medicines taken at the same time.
• Tell your doctor about all medicines, supplements, or herbals you are currently taking or might take to avoid any possible interaction.
• Jakura Tablet when given along with ketoconazole, itraconazole, ritonavir, nefazodone, telithromycin increases the level of Jakura Tablet in the body.
• Jakura Tablet when given along with rifampicin decreases the level of Jakura Tablet in the body.
• Care should be taken when the Jakura Tablet is administered along with medicines like fluconazole, tacrolimus, and cyclosporine.

Storage and disposal

• Store in a cool and dry place away from direct sunlight.
• Keep away from children and pets.

Frequently Asked Questions (FAQs)

What is rheumatoid arthritis and what are its signs and symptoms?

Rheumatoid arthritis is an inflammatory disease where your immune system attacks your own body's tissues and causes swelling, pain, and discomfort in your joints. Rheumatoid arthritis is a long-term disease and the signs and symptoms of the disease include pain, swelling, & stiffness in one or more joints, weight loss, fever, tiredness, and weakness.

How long does it take for Jakura Tablet to work?

Jakura Tablet starts working as soon as you start with the treatment . However, the improvement in your symptoms might take a few weeks depending on the severity of your condition and its physiology. Talk to your doctor for more infromation.

Does Jakura Tablet cause changes in weight?

No, Jakura Tablet does not have weight gain or weight loss as common side effect. However, if you think you are experiencing changes in weight, talk to your doctor.

Is hair loss a side effect of the Jakura Tablet?

No, hair loss was not reported as a side effect of taking Jakura Tablets. If you have any concerns about hair loss while taking this medicine, talk with your doctor.

Is Jakura Tablet an anti-inflammatory medicine?

Jakura Tablet is an anti-rheumatoid medicine that is used to reduce the signs and symptoms of rheumatoid arthritis. Jakura Tablet reduces the inflammation of the joints that occurs because of rheumatoid arthritis.

Will my immune system be suppressed if I take Jakura Tablets?

Rheumatoid arthritis is an inflammatory disease where your immune system attacks your own body's tissues and causes swelling, pain, and discomfort in your joints. Jakura Tablet is an anti-inflammatory immunosuppressant medicine that reduces the activity of the immune system. This reduction in activity reduces the pain, swelling, and discomfort of the joints in rheumatoid arthritis.