Jardiance Met Tablet

Jardiance MetTablet is an anti-diabetic medication. It contains a combination of empagliflozin and metformin as active substances. Jardiance MetTablet is used for the management of type 2 diabetes in adults along with diet and exercise.

Type 2 diabetes is a condition where your pancreas does not make enough insulin to effectively control the blood sugar level and your body is unable to use its own insulin effectively. This medicine works by lowering the blood sugar level. Take Jardiance MetTablet in the exact dose and duration as prescribed by your doctor.

Before starting this medicine, inform your doctor if you are pregnant/breastfeeding and about your complete medical history. It is important to make certain lifestyle changes like having a balanced diet and regular exercise along with this medicine to help to manage blood sugar levels better.

Dosage

Overdose

• If you think you have taken too much of Jardiance MetTablet, contact your doctor immediately or visit the nearest hospital.

Missed a Dose

• You should never miss your blood sugar medicines as they may lead to fluctuations in your blood sugar level.
• However, if you missed any dose of Jardiance MetTablet, take it as soon as you remember.
• If it's time for your next dose, then skip the missed dose and continue with your regular dosing schedule.
• Do not take a double dose to compensate for the missed one.

Mode of Action

How Does It Work?

Jardiance MetTablet contains a combination of empagliflozin and metformin as active substances. Empagliflozin is a sodium-glucose co-transporter-2 (SGLT2) inhibitors. It blocks the SGLT2 protein which causes the excretion of blood sugar through urine by preventing the reabsorption by the kidney. Metformin stops the production of glucose and also reduces its absorption in the body.

Directions for Use

• Take Jardiance MetTablet as a whole with sufficient water.
• Always take this medicine exactly as prescribed by your doctor.
• Take this medicine at the same time every day, preferably with meals for optimal benefits.
• Do not cut, break or chew the medicine.
• Do not consume more than the prescribed dose.
• Do not discontinue the medicine on your own without consulting your doctor.

Precautions and Warnings

Pregnancy

Can I take Jardiance Met 12.5mg/500mg Strip Of 10 Tablets during pregnancy?

There is limited information on the effect of Jardiance MetTablet during pregnancy. This medicine can be taken by pregnant women only if it is prescribed by your doctor.

Breast Feeding

Can I take Jardiance Met 12.5mg/500mg Strip Of 10 Tablets while breastfeeding?

Jardiance MetTablet may pass into human breast milk. So, this medicine should not be used during breastfeeding.

Driving

Can I drive if I have consumed Jardiance Met 12.5mg/500mg Strip Of 10 Tablets?

Jardiance MetTablet may have a minor effect on driving ability. If you experience any effects after taking this medicine that may affect your ability to drive safely, it is advised to avoid driving.

Alcohol

Can I consume alcohol with Jardiance Met 12.5mg/500mg Strip Of 10 Tablets?

No, alcohol should not be consumed with Jardiance MetTablet as it can increase the risk of lactic acidosis.

Other General Warnings

Talk to your doctor if

• You have a kidney or liver disorder.
• You have uncontrolled diabetes or a serious infection.
• You have been fasting for a long duration or you consume alcohol.
• You are dehydrated (due to severe vomiting/diarrhoea, fever, excessive heat or reduced fluid intake).
• You have a disease in which a part of the body has a reduced supply of oxygen.
• You develop any symptoms of lactic acidosis like vomiting, stomach pain, muscle cramps, a general feeling of not being well, tiredness, difficulty in breathing and reduced body temperature.
• You experience symptoms like rapid weight loss, nausea, vomiting, stomach pain, excessive thirst, fast and deep breathing, confusion, unusual sleepiness or tiredness, a sweet smell to your breath, a sweet or metallic taste in your mouth or a different odour to your urine or sweat after taking this medicine.
• You have type 1 diabetes – a condition where your body does not produce any insulin.
• You are not able to eat or drink.
• You are taking medicines called diuretics that increase the production of urine or lower blood pressure.
• You are elderly (over 75 years old).
• You have a serious infection of the kidney or the urinary tract with fever.
• You need to undergo an examination with iodination contrast agents (such as an X-ray or scan).
• You develop symptoms like pain, tenderness, redness, swelling of the genitals or the area between the genitals and the anus with fever or feeling generally unwell.

Contraindications

• If you are allergic to empagliflozin, metformin or any of the other ingredients of Jardiance MetTablet.
• If you have any type of metabolic acidosis (a condition where there is too much acid in the body fluids) like lactic acidosis or diabetic ketoacidosis.
• If you had a diabetic pre-coma.
• If you have kidney failure or liver problems.
• If you have any condition which may affect your kidneys like severe infection, dehydration (due to severe vomiting/diarrhoea or less fluid intake) or shock.
• If you have any disease which may cause a deficiency of oxygen supply to the tissues, like heart failure, respiratory failure, recent heart attack or shock.
• If you drink large amounts of alcohol.

Side effects

• Nausea
• Vomiting
• Abdominal pain
• Diarrhoea
• Loss of appetite

Interactions

Interactions with other medicines

• Some medicines can affect the way Jardiance MetTablet works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
• Inform your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.
• Particular care should be taken if you are taking medicines for treating fluid accumulation (diuretics), medicines that lower blood sugar levels (insulin, sulphonylurea), irregular/abnormal heartbeat (verapamil), tuberculosis (rifampicin), ulcers/stomach acidity (cimetidine), HIV (dolutegravir), heart-related chest pain (ranolazine), bacterial infections (trimethoprim), cancer (vandetanib, crizotinib, olaparib), fungal infections (isavuconazole), asthma (beta-2 agonists like salbutamol), inflammation (corticosteroids like prednisone), pain and inflammation (NSAID and COX-2-inhibitors like ibuprofen and celecoxib), high blood pressure (ACE inhibitors like enalapril and angiotensin II receptor antagonists like losartan), medicines that contain alcohol, iodinated contrast agents (medicines used during an X-ray or scan).
• Jardiance MetTablet may lower the levels of lithium (used to treat mental disorders) in the blood.

Storage and disposal

• Store Jardiance MetTablet in a cool and dry place away from direct sunlight.
• Keep it out of reach of children and pets.

Frequently Asked Questions (FAQs)

What is Jardiance MetTablet used for?

Jardiance MetTablet is used for the management of type 2 diabetes in adults along with diet and exercise.

When to take Jardiance MetTablet?

• Take Jardiance MetTablet exactly as recommended by your doctor.
• Take this medicine with meals to avoid a stomach upset.
• Preferably take it at the same time every day for optimal benefits.