Jointace DN Tablet

Jointace DN tablet is used in the treatment of osteoarthritis of the knee and hip joint. It is a combination medicine containing methyl sulfonyl methane (MSM), diacerein and glucosamine as the active ingredients. It reduces the pain and swelling at the joint by tackling the inflammation.

Jointace DN tablet promotes ease of movement by reducing the friction between the joints. They do so by increasing the cushioning effect between the joints. It should be taken as directed by the doctor and in doses and duration as prescribed.

You may experience diarrhoea, headache, nausea and stomach pain after taking Jointace DN tablet. If these symptoms do not resolve or worsen, consult your doctor. Inform your doctor if you are pregnant, planning a pregnancy or breastfeeding and about all the medicines and supplements you take and all the conditions or diseases you suffer from, before starting Jointace DN tablet.

Dosage

Overdose

Taking more than the recommended dosage of Jointace DN tablet can cause headache, dizziness, confusion, joint pain, nausea, vomiting, severe diarrhoea or constipation. If you have taken too much of this medicine then contact your doctor or reach out to the nearest hospital immediately.

Missed a Dose

If you have missed taking any dose of Jointace DN tablet then take it as soon as you remember. If it's already time for the next dose then skip the missed dose and follow the regular dosing schedule.

Mode of Action

How Does It Work?

• Methyl Sulfonyl Methane (MSM) acts as a nutritional supplement to the bones. It contains sulphur which is vital in the production of collagen and glucosamine, which in turn help in strengthening and repairing the bones and joints.
• Diacerein works by blocking the actions of a chemical substance called interleukin-1 beta, which leads to swelling, pain, and degradation of cartilage at the joints. It also helps in the built-up of cartilage thereby aiding in joint repair and healing.
• Glucosamine is a chemical substance found in the fluid around the joints (synovial fluid). It helps the synthesis of synovial fluid which keeps the joints lubricated and provides better movement and flexibility. It promotes the built-up of cartilage thereby helping in joint repair and reduces pain and improves its healing.

Directions for Use

• Jointace DN tablet should be taken as directed by your doctor.
• Swallow the tablet as a whole with a glass of water.
• Do not chew, break or crush the tablet
• Take the tablet at a fixed time for optimal results.
• Check the expiry date before use.

Precautions and Warnings

Pregnancy

Can I take Jointace DN tablet during pregnancy?

Jointace DN tablet is not recommended during pregnancy as there is limited information available about the effect of Jointace DN tablet on pregnant women and the developing foetus. Inform your doctor about all the medicine you are taking during pregnancy.

Breast Feeding

Can I take Jointace DN tablet while breastfeeding?

Jointace DN tablet is not recommended to be used by a breastfeeding mother, as a component of this medicine passes into the breast milk. Talk to your doctor if you are a nursing mother.

Driving

Can I drive if I have consumed Jointace DN tablet?

Jointace DN tablet may make you feel drowsy. Do not drive if you are experiencing side effects like drowsiness and headache.

Alcohol

Can I consume alcohol with Jointace DN tablet?

It is not recommended to consume alcohol while on Jointace DN tablet as it can alter the effect of medicine and may increase the side effects. Talk to your doctor if you have a habit of consuming it too often.

Other General Warnings

Talk to your doctor if

• You have a history of or are suffering from liver, heart or kidney disease.
• You have any other joint disease/ condition to find out the exact cause.
• You are suffering from diabetes or asthma.
• You are suffering from increased cholesterol levels.
• You are on antibiotics for any other medical condition, as it may increase the risk of stomach problems.
• You are pregnant, you think you may be pregnant and breastfeeding.
• You have experienced diarrhoea due to Jointace DN tablet earlier.
• You had electrolyte imbalance or dehydration due to any other medicine in past.
• Jointace DN tablet is not recommended for use in children below 18 years of age.

Contraindications

• If you are allergic to glucosamine, diacerein, and Methyl Sulfonyl Methane (MSM) or any other component of Jointace DN tablet.
• If you are suffering from liver disease and/or severe kidney damage.
• If have a history of or are suffering from obstruction of the intestine.
• If you are or were suffering from food pipe or intestinal disease like ulcerative colitis, Crohn’s disease.
• If you are prone to or are suffering from stomach ache.
• If you are allergic to shellfish.

Side effects

• Nausea
• Vomiting
• Headache
• Drowsiness
• Tiredness
• Diarrhoea
• Indigestion, gases
• Constipation
• Stomach pain
• Rash, itching

Interactions

Interactions with other medicines

• Some medicines can affect the way the Jointace DN tablet works or Jointace DN tablet itself can affect the action of other medicines taken at the same time.
• Tell your doctor about all the medicines you are currently taking, recently taken or might take to avoid any possible interactions.
• Particularly, if you are on medicines used to treat acidity, immunosuppressant medicines like doxorubicin, etoposide, teniposide, medicines used to treat heart failure, high blood pressure and/ or antibiotics to treat certain medical conditions.
• Patients with uncontrolled diabetes must use this medicine with caution as concomitant use of Jointace DN tablet with antidiabetic medicine such as glipizide, glyburide, and metformin may decrease the effect of blood sugar-lowering medicines.
• Use of Jointace DN tablet with blood-thinning medicines like warfarin can increase the risk of bleeding.

Storage and disposal

• Store at a temperature below 25°C in a cool dry place.
• Keep out of reach of children and pets.
• Dispose of the tablet if it has passed its expiry date

Frequently Asked Questions (FAQs)

What will happen if I accidentally take more than the recommended dosage of Jointace DN tablet?

In case you take an excess of this medicine you may experience adverse reactions like headache, dizziness, confusion, joint pain, nausea, vomiting, severe diarrhoea or constipation. Please contact your doctor or reach out to the nearest hospital immediately in such a case.

Can Jointace DN tablet be given to children?

No, Jointace DN tablet is recommended to be used only by adults and not in children below 18 years of age.

I have experienced diarrhoea on taking Jointace DN tablet, is it normal?

Diarrhoea is a common side effect of this medicine, typically during the initial phase of the treatment. This side effect is usually mild and short-lived. Please consult your doctor if you are experiencing severe diarrhoea, or persistent diarrhoea for many days.

I have diabetes can I take Jointace DN tablet.

Please talk to your doctor and inform him/her about your diabetes, also whether you are taking any antidiabetic medicines as this medicine can alter your blood glucose levels. Take this medicine only after being prescribed by your doctor.