Losar-H Tablet

Losar-H tablet is an anti-hypertensive medicine. It contains a combination of hydrochlorothiazide and losartan as active substances. Losar-H tablet is used to manage high blood pressure when it cannot be controlled using only losartan or hydrochlorothiazide.

It works by relaxing the blood vessels and removing more water and salt from the body, which helps to lower the raised blood pressure. Take this medicine in the exact dose and duration recommended by your doctor. Do not take more than the prescribed dose.

Do not stop taking this medicine on your own. Before starting Losar-H tablet, inform your doctor if you are pregnant, planning on becoming pregnant, breastfeeding and about your complete medical history. Along with taking this medicine, it is recommended to make specific lifestyle changes like eating a balanced diet, reducing salt intake, exercising regularly and avoiding smoking and alcohol to control your blood pressure levels.

Losar-H tablet should not be used in children and adolescents under 18 years of age.

Dosage

Overdose

• Symptoms of an overdose of Losar-H tablet may include low blood pressure, irregular heart rhythms, dizziness, excessive urination, nausea, and vomiting.
• If you think you have taken too much of this medicine, contact your doctor immediately or visit the nearest hospital.

Missed a Dose

• It would be best if you never miss a dose of your blood pressure medicine as it may lead to fluctuations in your blood pressure levels.
• However, if you have missed taking any dose of Losar-H tablet, take it as soon as you remember.
• If it is time for the next dose, skip the missed dose and continue with your regular dosing schedule.
• Do not take a double dose of this medicine to compensate for the missed one

Mode of Action

How Does It Work?

• Losar-H tablet contains a combination of hydrochlorothiazide and losartan as active substances.
• Losartan lowers blood pressure by blocking the action of a substance called angiotensin responsible for the narrowing of blood vessels and hence causing a rise in blood pressure.
• Hydrochlorothiazide acts by increasing the production of urine and the loss of water and salt from the body. This helps to lower blood pressure.

Directions for Use

• Losar-H tablet should be taken exactly as recommended by the doctor.
• Swallow it as a whole with a glass of water.
• Do not crush, break, or chew the medicine.
• Do not take more than the prescribed dose.

Precautions and Warnings

Pregnancy

Can I take Losar-H tablet during pregnancy?

Losar-H tablet is not recommended for use during the first 3 months of pregnancy. This medicine should not be used in women who are more than 3 months pregnant. Inform your doctor if you are pregnant or planning on becoming pregnant before starting this medicine. Also, if you become pregnant while taking this medicine, talk to your doctor immediately.

Breast Feeding

Can I take Losar-H tablet while breastfeeding?

Losar-H tablet is not recommended during breastfeeding. Inform your doctor if you are breastfeeding before starting this medicine.

Driving

Can I drive if I have consumed Losar-H tablet?

Losar-H tablet may cause dizziness or drowsiness. If you experience any such effects after taking this medicine that may affect your ability to drive safely, it is advised to avoid driving.

Alcohol

Can I consume alcohol with Losar-H tablet?

No, alcohol should not be consumed with Losar-H tablet as it may cause orthostatic hypotension (a type of low blood pressure that occurs when you stand up after sitting down or lying).

Other General Warnings

Talk to your doctor if

• You have any kind of pre-existing health condition such as heart-related disorder, diabetes, kidney or liver disorder, skin cancer, gout, an autoimmune disorder like systemic lupus erythematosus, etc.
• You develop symptoms like swelling of the face, lips, throat or tongue due to water retention.
• You experience fainting and dizziness, especially after the first dose.
• You are planning a pregnancy, this medicine will be changed.
• Your kidneys are not functioning correctly or you have underlying kidney disease like renal artery stenosis (Narrow kidney blood vessels).
• You have been experiencing fluid losses within your body due to diarrhoea, vomiting, etc.
• You are suffering from primary aldosteronism (a condition of excess production of the hormone aldosterone from the adrenal glands).
• You have electrolyte imbalance of sodium, magnesium, potassium and have symptoms of dryness of mouth, thirst, drowsiness, muscle pain, nausea, vomiting, etc.
• You have galactose intolerance (small intestine's inability to transport and absorb glucose and galactose).
• You develop eye pain and a decrease in vision.

Contraindications

• If you are allergic to hydrochlorothiazide, losartan, or any of the ingredients of Losar-H tablet.
• If you are allergic to sulfonamide medicines such as co-trimoxazole. If you are not sure what these medicines are, please confirm with your doctor.
• If you have a low level of potassium and sodium or high levels of calcium in your blood
• If you have serious liver disorders and problems related to the bile duct (a canal connecting the liver to the intestine) like cholestasis.
• If you have anuria (not passing urine or passing urine less than 100ml in a day).
• If you have diabetes or kidney problems and you are taking a medicine containing aliskiren.
• If you have gout.
• If you are pregnant for more than 3 months.

Side effects

• Nausea
• Diarrhoea
• Abdominal pain
• Indigestion
• Tiredness

Interactions

Interactions with other medicines

• Some medicines can affect the way how Losar-H tablet works or this medicine itself might affect the working of other medicines.
• Inform your doctor about all the medicines, herbals, or supplements that you are currently taking or might take to avoid any possible interaction. Also, you should inform your doctor if you have a planned surgery or vaccination scheduled.
• Especially, if you are on certain medications like blood thinners (warfarin or heparin), anti-cancer medicines, medicines used to treat high cholesterol such as cholestyramine, antidepressants like lithium, potassium supplements or medicines containing potassium, other antihypertensives like water pills (furosemide), medicines for heart-related disorders like digoxin, etc.
• If you have diabetes, do not take aliskiren along with this medicine.
• Steroidal medicines if taken along with this medicine can lead to salt imbalances particularly reduced potassium levels.
• Concomitant use of Losar-H tablet and painkillers should be avoided as it may impair kidney functions.
• Other medicines that should be used with caution are antibacterial medicines such as trimethoprim, corticosteroids used to treat the inflamed area of body parts, etc.

Interactions with food items

Losar H can be taken with or without food. However, taking it with food may help reduce gastrointestinal discomfort. It is advisable to avoid potassium supplements and foods high in potassium.

Storage and disposal

• Store Losar-H tablet below 30°C protected from light and moisture.
• Keep away from children and pets.

Frequently Asked Questions (FAQs)

Will Losar-H tablet start lowering my blood pressure immediately after I take this medicine?

Blood pressure will not start to lower immediately after you start taking Losar-H tablet. It will take 3-4 weeks for your blood pressure to be normalized. It is advised to take this medicine exactly as recommended by your doctor for the prescribed duration. Do not stop taking this medicine on your own.

Can I use Losar-H tablet if I have kidney or liver disease?

Before using Losar-H tablet, inform your doctor about your medical history and all the medicines that you are taking. Based on this information, your doctor will decide if it is suitable for you to take this medicine if you have liver or kidney disease.

Is there anything else I need to know before using Losar-H tablet?

• Your blood pressure, kidney function, and blood potassium levels need to be regularly monitored while you are taking this medicine.
• Inform your doctor if you are undergoing any radiography with iodine contrast media.
• Losar-H tablet should not be used in children and adolescents under 18 years of age.