Ofnis Oz Tablets

Ofnis Oz tablet is an antibiotic combination medication containing ofloxacin and ornidazole. It is indicated for the treatment of diarrhoea caused by mixed bacterial infections in adults. Ofloxacin functions by inhibiting bacterial DNA gyrase, an enzyme essential for bacterial DNA replication and repair, thereby preventing bacterial growth.

Ornidazole acts by damaging bacterial DNA, leading to bacterial cell death. The combined action of these two agents targets a broad spectrum of bacteria responsible for gastrointestinal infections. The dosage and duration of treatment are determined by a healthcare professional based on the infection's severity and patient-specific factors.

Adherence to the prescribed regimen is crucial to ensure treatment efficacy and minimize the risk of antibiotic resistance. Patients should inform their doctor about any existing medical conditions or concurrent medications.

Dosage

Overdose

• Symptoms of overdose include drowsiness, hot and cold flushes, nausea, dizziness, facial swelling, numbness, slurring of speech and disorientation
• In case of an overdose, contact your doctor immediately or visit the nearest hospital

Missed a Dose

If you missed any dose of medicine, take it as soon as you remember If it's time for your next dose, skip the missed dose and continue with your regular dosing schedule Do not take a double dose of medicine to compensate for the missed one It is advisable not to miss any dose of antibiotics as it can result in failure of therapy

Mode of Action

How Does It Work?

Ofloxacin works by inhibiting the growth of bacteria and Ornidazole kills the bacteria.

Usage Instructions

Administer this medicine as directed by a healthcare professional.

Precautions and Warnings

Pregnancy

Can I take Ofnis Oz tablet during pregnancy?

• It is preferable to avoid Ofnis Oz tablet if you are pregnant, think you might be pregnant or are planning to have a baby as this medicine may harm your baby
• If you conceive while taking this medicine, stop taking this medicine immediately and inform your doctor

Breast Feeding

Can I take Ofnis Oz tablet while breastfeeding?

It can pass into human breast milk and can harm your child. Hence, breastfeeding should be discontinued while you are taking this medicine.

Driving

Can I drive if I have consumed Ofnis Oz tablet ?

You may experience sleepiness, dizziness, visual disturbance, poor coordination, vertigo, temporary loss of consciousness, rigidity or impairment of skills. It is advisable not to drive if you experience such symptoms.

Alcohol

Can I consume alcohol with Ofnis Oz tablet ?

It is advised not to consume alcohol during the treatment as it may worsen the side effect like dizziness.

Other General Warnings

Talk to your doctor if

• If you feel strain/ pain on tendons (tendinitis), immediately stop this medicine, do not move the joint and inform your doctor immediately
• If you are experiencing continuous or bloody diarrhoea
• If you have diabetes, your blood glucose can drop when you are on this medicine
• If you have myasthenia gravis, this medicine can worsen it
• If you experience suicidal thoughts, immediately inform your doctor
• If you experience fits or have a history of fits
• If you feel restlessness, lightheadedness, confusion or hallucinations
• If you feel allergic reactions like fever or rashes
• If you have kidney problem or heart problem
• If you have glucose-6-phosphate dehydrogenase deficiency (an inherited disorder that affects red blood cells)

Contraindications

• If you are allergic to this medicine or any of the ingredient of this medicine
• If you are allergic to the class of medicines called Fluoroquinolone
• If you have a history of fits (epilepsy)
• If you have problems related to tendon (tissue connecting muscles to bones) like inflammation and swelling of the tendons (tendonitis)
• If you are pregnant or are planning to have a baby or if you are breastfeeding
• If your age is less than 18 years
• If you have Glucose-6-Phosphate Dehydrogenase deficiency (an inherited disorder that affects red blood cells) or a family history of this deficiency

Side effects

• Nausea, vomiting or diarrhoea
• Dry mouth
• Loss of appetite
• Rash
• Headache
• Sleep disturbance
• Constipation
• Disturbance in attention
• Altered mental state
• Stomach ache
• Aggression
• Nervousness
• Low blood sugar if you have diabetes and on medicines or insulin
• Tendon disorders like tendon rupture(serious)

Interactions

Interactions with other medicines

• This medicine contains Ofloxacin and Ornidazole. Any interaction which is seen with any of these two components when taken alone may occur with this combination too
• Medicines used to treat acidity (antacids) like Sucralfate, antacids containing calcium and magnesium should not be taken two hours before or after this medicine
• Medicines used to treat a certain type of stomach ulcers like Cimetidine
• Medicines used to treat pain and inflammation (NSAID's) can increase the chance of fits
• Medicines used to treat asthma or chronic obstructive pulmonary disease (COPD) like Theophylline
• Increased chances of bleeding if taken along with Warfarin
• Blood sugar can drop if you are on insulin, Glibenclamide and thus careful monitoring of blood glucose is needed
• Medicines used to treat depression like Lithium
• Medicines used to treat fits or epilepsy (antiepileptic) like Phenytoin and Phenobarbital

Interactions with food items

Food does not affect the way this medicine works. It can be taken with food.

Storage and disposal

• Store the medicine in a cool and dry place
• Protect it from light
• Keep it out of the reach of children

Frequently Asked Questions (FAQs)

What should I avoid while taking this medicine?

• Avoid exposure to direct sunlight
• Wear a protective covering or use sunscreen (SPF 30 or 40) to prevent sunburn
• Avoid dehydration by having plenty of fluids

For how many days do I need to take this medicine?

Take this medicine as per your doctor's prescribed duration. Though you may feel better after a few doses, you must complete the course or the infection may reoccur.