Nintena 150 Softgel Capsule

Nintena 150 Soft Gelatin capsule is used to treat a rare lung disease known as Idiopathic Pulmonary Fibrosis (IPF). It is also prescribed for specific forms of lung cancer in combination with another anticancer medication called docetaxel. The active ingredient in Nintena 150 Soft Gelatin capsule is nintedanib, which works by reducing the activity of certain enzymes called tyrosine kinases that contribute to fibrosis (scarring), thereby helping to slow the scarring of the lungs.

For optimal results, take Nintena 150 Soft Gelatin capsule with food at the same time every day. Your doctor will determine the appropriate dosage and schedule for you, which may be adjusted as necessary. Follow your doctor's instructions carefully, as improper use or an overdose can lead to serious side effects.

Do not discontinue this medication without consulting your doctor, even if it takes weeks or months to notice any benefits. A very common side effect of this medicine is diarrhea. It is essential to drink plenty of fluids and consult your doctor if symptoms persist.

Other common side effects may include nausea, stomach pain, vomiting, weight loss, high blood pressure, and headaches. Your doctor may also order blood tests to monitor your liver function. Before starting Nintena 150 Soft Gelatin capsule, inform your doctor if you have any bleeding problems or issues with your liver or kidneys.

Additionally, please inform your healthcare team about all other medications you are taking, as many can interact with this medication. Nintena 150 Soft Gelatin capsule is not recommended for use during pregnancy or while breastfeeding. To prevent pregnancy, both male and female patients are advised to use effective contraception during treatment.

Dosage

Missed a Dose

If you have missed taking a dose of Nintena 150 Soft Gelatin capsule, take your next dose at your regular time. Do not take the missed dose.

Overdose

Seek immediate medical help in case of an overdose. Do not exceed the recommended daily dose of this medicine.

Mode of Action

How Does It Work?

• Nintena softgel capsule works by inhibiting the action of tyrosine kinases, an enzyme involved in the development of lung fibrosis. This enzyme is also involved in the process of forming new blood vessels in tumour cells.
• By inhibiting these enzymes, this medicine can help slow down scarring and the progression of cancer.

Directions for Use

• Nintena 150 Soft Gelatin capsule should be taken as directed by your doctor.
• Swallow it whole with a glass of water; do not cut, break, or chew the medicine.
• It should be taken with food.
• It is best to take it at a fixed time for optimal results.
• You should not consume it more than that prescribed by your doctor.

Precautions and Warnings

Pregnancy

Can I take the Nintena softgel capsule during pregnancy?

Nintena softgel capsule should not be taken by a pregnant woman as it can harm the unborn baby. Consult your doctor before using it during pregnancy. Women should not become pregnant while taking this medicine and use highly effective birth control during treatment and for at least 3 months after treatment.

Breast Feeding

Can I take the Nintena softgel capsule while breastfeeding?

It is not known if the component of the Nintena softgel capsule passes into the breastmilk. Consult your doctor before using it while breastfeeding. Nintena softgel capsule

Driving

Can I drive if I have consumed the Nintena 150 Soft Gelatin capsule?

Nintena 150 Soft Gelatin capsule has a minor influence on the ability to drive and use machines. Be cautious if you experience any symptoms that affect your ability to stay alert.

Alcohol

Can I consume alcohol with the Nintena softgel capsule?

There is limited information available on the interaction of the Nintena softgel capsule with alcohol. Consult your doctor if you have a regular habit of drinking.

Other General Warnings

Talk to your doctor if

• You have a liver, heart or family history of bleeding problems.
• You have a history of a blood-clotting disorder, or you smoke.
• You have had recent surgery in your stomach (abdominal) area.
• You are pregnant, planning a baby, or breastfeeding.

Contraindications

• If you are allergic to nintedanib or any other ingredients of this medicine.
• If you are allergic to peanuts or soya.
• This medicine should never be used during pregnancy.

Side effects

• Nausea
• Vomiting
• Diarrhoea
• Headache
• Stomach pain
• Decreased appetite

Interactions

Interactions with other medicines

• Certain medicines can affect the way the Nintena 150 Soft Gelatin capsule works, or this medicine itself can interact with the action of other medicines taken concurrently.
• Therefore, it is essential to inform your doctor about all the medications, supplements, or herbal products you are currently taking or may take in the future.
• In particular, if you are taking a blood thinner, additional monitoring is required as Nintena 150 Soft Gelatin capsule can increase the risk of bleeding.
• Concomitant administration of anti-infective medicines such as erythromycin and rifampicin; medicines for brain-related disorders such as phenytoin, carbamazepine and St. John’s wort should be avoided.

Interactions with food items

Nintena 150 Soft Gelatin capsule should be taken with meals to improve its effectiveness.

Storage and disposal

• Store the Nintena 150 Soft Gelatin capsule below 25°C. Protect from light and moisture.
• Keep it out of the reach and sight of children and pets.

Frequently Asked Questions (FAQs)

Can I take the Nintena softgel capsule on an empty stomach?

No, the Nintena softgel capsule should be taken with food and a sufficient amount of water. Do not crush or chew the medicine.

What are the side effects of the Nintena softgel capsule?

You may experience nausea, vomiting, stomach pain, headache, and other side effects after taking this medicine. But not everybody taking this medicine experiences these side effects.

What is Idiopathic Pulmonary Fibrosis?

Idiopathic Pulmonary Fibrosis is a lung condition in which the tissue of the lungs becomes scarred, which makes the lungs unable to transport oxygen into the bloodstream effectively. It may be caused by abnormal tissue repair following tissue damage.