Pause 500 Tablet

Pause 500 tablets are used to prevent excessive bleeding in conditions that cause bleeding from the body, such as nosebleeds, surgery, menstruation, and internal bleeding. The active ingredient in this medication is tranexamic acid, a type of antifibrinolytic medication. Pause 500 works by preventing the breakdown of clots, thereby stopping the bleeding.

It is important to follow the doctor's instructions when taking this medicine, including the recommended dose and duration. To avoid stomach discomfort, take Pause 500 with food. Do not exceed the prescribed dose.

Some common side effects of the Pause 500 tablet are nausea and vomiting, but not everybody gets them. These side effects typically subside over time, but if they persist, you should consult your doctor. Trenaxa 500mg tablets , Melano Tx Od 500mg tablets , Trapic 500mg tablet , Tyrodin Fsr 500mg tablets and Texakind 10 tablets are some other medicines with tranexamic acid as its active ingredient.

Dosage

Overdose

• If you accidentally end up taking a dose higher than that prescribed, you may experience symptoms like feeling sick, nausea and vomiting or be dizzy or light-headed upon standing.
• If you experience any of the symptoms or think you have taken too much of Pause 500 tablet, contact your doctor immediately or visit the nearest hospital.

Missed a Dose

• Missing a dose of Pause 500 tablet may reduce the effectiveness of the treatment.
• If you missed any dose of medicine take it as soon as you remember.
• If it's time for your next dose, skip the missed dose and continue with your regular dose schedule.
• Do not take a double dose of medicine to compensate for the missed one.

Mode of Action

How Does It Work?

• Blood clotting is a complex process and involves various enzymes in different steps. Tranexamic acid is a structural analogue of an amino acid lysine which important for blood clotting process.
• Tranexamic acid helps in arresting bleeding by binding to certain receptors where lysine binds, inhibiting the enzymes that break down the blood clots. Hence, it helps to stop excessive bleeding.

Directions for Use

• Take Pause 500 tablet as told by your doctor with a sufficient amount of water, and swallowed whole. Do not crush or chew the tablets.
• You should take this medicine regularly, as directed by your doctor.
• You should not consume it more than that prescribed by your doctor.
• If the bleeding does not stop, contact your doctor; you may need further evaluation.

Precautions and Warnings

Pregnancy

Can I take Pause 500 during pregnancy?

• There is limited information about the effects of Pause 500 in human pregnancy
• It is known to cross the placenta and is found in the cord blood at concentrations equal to that in maternal blood
• It should be used when prescribed considering that the benefit of taking this medicine outweighs the risk
• It is better to consult your doctor before taking this medicine in pregnancy

Breast Feeding

Can I take Pause 500 while breastfeeding?

• Pause 500 passes into human milk in a small amount
• If a breastfeeding mother requires tranexamic acid, it is not a reason to discontinue breastfeeding. However, close monitoring and medical supervision of the breastfed infant is recommended until more data regarding safety becomes available
• It is advisable to consult a doctor before initiating the medicine during breastfeeding

Driving

Can I drive if I have consumed Pause 500?

Pause 500 does not directly affect alertness levels. Hence, driving is not contraindicated if taking this medicine. However, one should watch out for signs of blurring of vision or loss of colour vision which may appear as a side effect of this medication. Hence, regular eye check-ups in patients taking long term treatment with tranexamic acid are recommended.

Alcohol

Can I consume alcohol with Pause 500?

There is no data regarding interactions between Pause 500 and alcohol. However, this does not rule out the possibility of interaction and it is better to avoid alcohol consumption.

Other General Warnings

Talk to your doctor if

• You are suffering from kidney disease.
• You are passing blood in your urine. Pause 500 should be used with caution and only if prescribed by your doctor, as there is a risk of urinary passage obstruction due to blood clots.
• You have a history of blood clots in blood vessels or with a family history of the same, use Pause 500 only if it is prescribed to you by a doctor and insist on close monitoring of your health.
• You are suffering from excessive menstrual bleeding or irregular periods.
• You are taking oral contraceptive pills, and you should consult your doctor before consuming oral contraceptive pills and Pause 500 together, as there are increased chances of blood clot formation in your blood vessels.
• You experience visual disturbances, you should stop the medications and consult your doctor immediately.
• You may require regular eye check-ups if you are taking Pause 500 for an extended period, as recommended by a doctor.

Contraindications

• If you are allergic to tranexamic acid or any other ingredients of Pause 500 tablet.
• If you have kidney disease, it may lead to a reduction in the elimination of the active medicine from the body leading to its accumulation which can lead to toxic effects and hence not to be used in severe kidney disease.
• In mild to moderate kidney disease the medicine can be used with proper suggestions that have been recommended by the doctor.
• If you are currently having an episode or a history of different diseases arising because of clot formation in the body called thromboembolic diseases. Eg. Heart attack or paralysis due to clots in blood vessels in the brain, blood clots in vessels of the lower limbs etc.
• If you have a history of convulsions or fits.
• If you have blood disorders known to increase blood clotting tendencies.

Side effects

• Diarrhoea
• Vomiting
• Nausea

Interactions

Interactions with other medicines

• The effect of Pause 500 will be reduced if taken along with blood thinners (like warfarin, and heparin) which are medicines that inhibit clot formations
• An additive effect may be seen if the patient is taking medications that increase blood clot formation (like aprotinin)
• Oral contraceptive pills, when taken with Pause, may promote blood clot formation which can be harmful, leading to blockage of blood vessels by abnormal clot formation. Inform your doctor if you are taking birth control pills

Interactions with food items

Pause 500 Tablet can be taken with or without food. It has no known interactions with food.

Storage and disposal

• Store Pause 500 tablets below 25°C in a clean and dry place, protected from moisture, sunlight and heat.
• Keep this medicine away from children and pets.
• You should not flush this medicine in the toilet or pour them into the drain. You need to properly discard this medicine when it is expired or no longer needed.

Frequently Asked Questions (FAQs)

Can I take progesterone and Pause 500 together?

Pause 500 is usually prescribed to control excessive bleeding during menses. Your dose will be escalated based on the severity of your symptoms. However, for women who have repeated heavy cycles and other signs of hormonal imbalance, Progesterone pills maybe started to regulate the hormonal imbalance. This shall be done after evaluating your menstrual cycle, medical history and hormone levels by your gynaecologist.

Can I take Pause 500 to avoid getting menses?

The menstrual cycle is regulated by various female hormones like estrogen, progesterone and luteinizing hormone. Other hormones like prolactin and thyroid hormones also indirectly affect menstrual cycles. Pause 500 is effective only in controlling excessive bleeding during menses and is not recommended for controlling or stopping regular menstrual cycles. It is advisable to consult your gynaecologist for controlling menses.

For how many cycles can Pause 500 be taken?

If you are suffering from repeated heavy menstrual cycles, it is advisable to consult a gynaecologist. Though Pause 500 will control the excessive blood flow, it does not correct the underlying hormonal imbalance or other conditions that are actually responsible for causing the excessive flow. Hence, it is better to consult your gynaecologist and get a check-up done.

Can Pause 500 help me to get relief from abdominal pain during menses?

Abdominal pain during menses is induced as the uterus contracts strongly, giving rise to uterine cramps. Menses result from the shedding of the inner uterine lining, which leads to the formation of various chemical mediators. These mediators induce abdominal cramps. Pause 500 does not inhibit the action of these mediators and hence as such, does not have a direct painkiller effect. This medicine is basically used to control bleeding. However, as the bleeding subsides, the pain slowly reduces.

Can Pause 500 be used to control post-menopausal bleeding?

Post-menopausal bleeding is never considered normal. There is always an underlying disorder which leads to post-menopausal bleeding. It is important to first diagnose the disorder and treat the same. Post-menopausal bleeding should never be ignored and a gynaecologist should be immediately consulted.

Can I take paracetamol while I am taking Pause 500 mg?

No specific interactions have been observed between paracetamol and tranexamic acid. As every individual may have a unique physiological response, it is advised that you consult your doctor before use of this medicine.

Should I take Pause 500 with or without food?

Take Pause 500 tablet as recommended by your gynaecologist. Make sure you maintain a fixed time for taking the medicine daily.

Can I take Pause 500 for long term?

No, it is usually prescribed for a short duration. Take it for as long as the doctor has told you to take it. Do not exceed the prescribed duration.

Is there any side effect of Pause 500?

Diarrhoea, vomiting and nausea are a few common side effects of this medicine. However, these symptoms resolve with time. Inform your doctor if they persist for long.

How long does Pause 500 take to work?

Pause 500 contains tranexamic acid, which is a type of medicine called an anti-fibrinolytic. It can take up to 24 hours for the medicine to show full effect.

Can I use Pause 500 stop period?

No, Pause 500 is not intended to stop the period. It is used to treat and reduce excessive bleeding in menses (during periods).

Can Pause 500 tablet be used for piles?

Pause 500 is used to stop bleeding in various conditions. This medicine can be used to treat piles if advised by your doctor after assessing the condition and its severity.

How many tablets of Pause 500 can I take?

You should take Pause 500 in the exact dose and frequency prescribed by the doctor. The dose and frequency of Pause vary among individuals depending on the condition it is being taken for. You should not consume more than the recommended daily dose by the doctor.