Perjeta 420mg Vial Of 14ml Solution For Infusion

Perjeta 420mg Injection is an anticancer medication that contains pertuzumab, used to treat a specific type of breast cancer (HER2-positive) in conjunction with other chemotherapy drugs. Common side effects of this medication include hair loss, diarrhea, nausea, and fatigue. This medication may reduce the number of blood cells, specifically decreasing white blood cells, which can increase susceptibility to infections.

Regular blood tests are required to monitor your blood cells, as well as to check your heart, liver, and kidneys. Many other medications can affect or be affected by this treatment, so inform your healthcare team about all medications you are using. This medication is not recommended during pregnancy or while breastfeeding.

Both males and females must use effective contraception during treatment to prevent pregnancy. Please discuss all medications you are currently taking, including supplements and herbs, with your doctor before starting Perjeta. Additionally, it is important to inform your doctor if you have a history of heart problems or have previously undergone chemotherapy.

Dosage

Missed a Dose

Your doctor or nurse will carefully monitor and schedule your injections, making it unlikely for a dose to be missed. However, if you suspect a dose might have been overlooked, let them know immediately.

Overdose

Your doctor or nurse will give Perjeta 420mg Injection. Therefore, the chances of overdose are very rare. If you experience the symptoms right after taking the injection, seek medical help.

Mode of Action

How Does It Work?

Pertuzumab specifically targets a protein known as HER2, found on the surface of certain breast cancer cells. HER2 plays a crucial role in promoting the growth and division of these cells. Pertuzumab binds to a distinct part of the HER2 protein, impeding its proper function, which can help inhibit the growth and spread of cancer cells.

Directions for Use

This medicine will be given to you by your doctor or nurse. Self-administration is not advised.

Precautions and Warnings

Pregnancy

Can I take Perjeta 420mg Injection during pregnancy?

Perjeta 420mg injection is not advisable during pregnancy and for women of childbearing potential who are not using contraception.

Breast Feeding

Can I take Perjeta 420mg Injection while breastfeeding?

Perjeta 420mg Injection may be excreted in breast milk; therefore, a decision should be made regarding whether to discontinue breastfeeding or to halt treatment, considering the benefits of breastfeeding for the child and the advantages of Perjeta therapy for the woman.

Driving

Can I drive if I have taken Perjeta 420mg Injection?

Perjeta has a minor impact on driving or operating machines. Dizziness may occur during treatment, and patients with infusion reactions should avoid driving or using machines until symptoms improve.

Alcohol

Can I consume alcohol with Perjeta 420mg Injection?

No known interactions with alcohol.

Other General Warnings

Talk to your doctor if

• You have kidney disease or have undergone a kidney transplant.
• You have liver disease or a history of liver issues.
• You have a history of heart disease, including heart failure or diminished heart function.
• You are experiencing symptoms such as shortness of breath, swelling in the legs, or a rapid heartbeat during treatment.
• You have suffered severe allergic reactions to medications in the past.
• You are pregnant, planning to conceive, or breastfeeding.
• You experience severe diarrhoea, dehydration, or unusual fatigue during treatment.
• You develop a fever, chills, or other signs of infection.
• You notice any unusual swelling, rash, or hives after an infusion.
• You have a low white blood cell count or have experienced febrile neutropenia previously.
• You experience sudden changes in vision or severe headaches during treatment.
• You are taking other medications, including over-the-counter drugs or supplements, as they may interact with Perjeta.

Contraindications

If you have any allergy to pertuzumab or any other ingredient in this medicine.

Side effects

• Nasopharyngitis
• Upper respiratory tract infection
• Neutropenia
• Diarrhea
• Vomiting
• Stomatitis
• Nausea
• Alopecia
• Rash
• Pyrexia (Fever)
• Fatigue
• Asthenia (Weakness)

Interactions

Interactions with other medicines

Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.

Storage and disposal

• Store in a refrigerator (2° C-8° C).
• Do not freeze.
• Keep the vial in the outer carton in order to protect it from light.