Pipzo 4.5 g Powder For Injection

Pipzo 4.5 gm injection contains a combination of piperacillin and tazobactam as the active ingredients, Piperacillin is an antibiotic medicne and works by killing the bacteria responsible for infections. However, certain bacteria develop an enzyme (beta-lactamases) that can destroy Piperacillin as a resistance mechanism.

Tazobactam inactivates this enzyme and hence helps Piperacillin to function optimally. This medicine combination may be prescribed in the treatment of certain resistant or severe infections.

Dosage

Overdose

Your doctor or nurse will give this injection. Therefore, it is less likely to provide you with more or less of this medicine. However, if you experience loose motions, nausea, vomiting and fits immediately after taking this injection, inform your doctor as soon as possible.

Missed a Dose

You will be monitored by your doctor or nurse on when the injection should be given to you. It is unlikely that you will be missing any dose. However, if you think your doctor or nurse might have missed a dose, inform them. It is advisable not to miss any dose of antibiotics as it can result in the fail of the therapy.

Mode of Action

How Does It Work?

Pipzo 4.5 gm injection acts by killing the bacteria responsible for infections. However, bacteria make an enzyme (beta-lactamases) which can destroy Piperacillin. Tazobactam inactivates this enzyme and hence helps Piperacillin to function optimally.

Directions for Use

This medicine will be given in a hospital by your doctor or nurse as an injection. Do not self-inject this medicine.

Precautions and Warnings

Pregnancy

Can I take the Pipzo 4.5gm injection during pregnancy?

• It is not advisable to take this medicine during pregnancy as it passes the placental barrier.
• However, it can be given to you by your doctor if required after assessing the benefits over risks.
• Consult your doctor if you are pregnant, think you may be pregnant or are planning to have a baby.

Breast Feeding

Can I take the Pipzo 4.5gm injection while breastfeeding?

The components of this medicine pass into breastmilk and are known to cause fungal infections of the mouth and diarrhoea in babies. Consult your doctor if you are breastfeeding, your doctor will tell you about the use of this medicine after assessing the benefits over risks.

Driving

Can I drive if I have taken the Pipzo 4.5gm injection?

No information is available on the effect of this medicine on the ability to drive or use machines. However, if you experience any side effects like pain or swelling at the site of injection, do not drive.

Alcohol

Can I consume alcohol with the Pipzo 4.5gm injection?

No information is available on the interaction of this medicine with alcohol. However, consuming alcohol may exaggerate the side effects of this medicine. Thus, it is not advisable to consume alcohol when you are taking this medicine.

Other General Warnings

Talk to your doctor if

• You have a history of allergic reactions to Penicillin, Cephalosporins, Carbapenems.
• You develop serious skin disorders like painful rashes along with flu.
• You have diarrhoea and pus in your stool after taking this medicine, immediately stop the medicine and report to your doctor.
• You experience bleeding disorders or taking blood-thinning medicines like Warfarin.
• You experience fits or convulsions.
• You have problems with kidney function.
• You have weakness, fatigue, muscle cramps or low levels of potassium.

Contraindications

• If you are allergic to Piperacillin and Tazobactam or any of the ingredients of this medicine.
• If you have a history of severe allergic reactions to any other antibiotic like Cephalosporins, Monobactam and Carbapenem.

Side effects

• Diarrhoea
• Constipation
• Nausea
• Vomiting
• Indigestion
• Stomach pain
• Fever
• Anaemia
• Fungal infection (candidiasis)
• Headache
• Sleeplessness
• Rashes
• Itching
• Inflammation and swelling at the injection site

Interactions

Interactions with other medicines

• Medicines used to relax the muscles during surgery like Vecuronium.
• Close monitoring of blood function is required if you are on medicines used to stop blood-thinning like Warfarin.
• Medicines used to treat certain types of cancers like methotrexate.
• Medicines used to treat gout-like probenecid.
• If you have kidney problems and you are taking antibiotics like Tobramycin, Gentamicin and Vancomycin.

Storage and disposal

• Store this medicine at or below 25°C.
• Protect it from light and heat.
• Keep it out of the reach of children and pets.
• Any unused portion should not be stored and discarded properly.

Frequently Asked Questions (FAQs)

I am suffering from the flu-like common cold, can I take this medicine?

No, this medicine is used for treating severe infections caused by bacteria and not viral infections. This medicine should only be taken when prescribed by the doctor.

I am on a restricted salt diet, can I take this medicine?

No, as this medicine contains an ample amount of sodium, it is advisable to be very cautious and discuss your dietary restrictions with your doctor before taking this medicine.

Who should not take the Pipzo 4.5gm injection?

Pipzo 4.5 gm injection is not recommended for individuals suffering from liver and kidney disease, those who are allergic to active ingredients like antibiotics like Cephalosporins, Monobactam and Carbapenem.

What are the side effects observed after taking this medicine?

You may experience nausea, vomiting, indigestion, headache and pain, redness, swelling at the site of injection.

What is the composition of Pipzo injection?

The composition of Pipzo injection includes- piperacillin and tazobactam as the active ingredients that belong to an antibiotic class of medicines.

Can I stop the treatment with Pipzo injection if my symptoms resolve and I start feeling better?

No, you must complete the course of treatment as prescribed by the doctor. Abruptly stopping the treatment with antibiotics in midway may lead to recurring infections.

Can Pipzo injection be given in covid?

No, you should not take any medicine or self-inject any medication to treat or prevent COVID-19 without consulting a doctor. If you have been tested positive with COVID-19 immediately inform your doctor. Moreover, this injection will be given in a hospital by your doctor or nurse as an injection. Do not self-inject this medicine.

What are the indications of Pipzo injection?

Pipzo injection is indicated for the treatment of serious and complicated infections caused by bacteria such as stomach and abdominal infection, skin and soft tissue infections, diabetic foot infections due to diabetes and pneumonia. It is to be used only when an infection cannot be controlled by other antibiotics.