Powergesic MR Tablet

Powergesic MR tablet is a painkiller and fever-reducing medicine. It contains a combination of three medicines - diclofenac, paracetamol, and chlorzoxazone. It is used for the treatment of painful muscle spasms associated with musculoskeletal conditions.

It is also used to reduce swelling and inflammation of joints and bones. Powergesic MR tablet works by interfering with the production of chemicals responsible for inflammatory reactions such as prostaglandins. It relaxes the muscles by blocking pain signals to the brain from the site of pain.

You should take this medicine as prescribed by your doctor. Do not take this medicine for relieving pain before, during, or after cardiac bypass surgery. Before using Powergesic MR tablet, inform the doctor if you are pregnant, planning a pregnancy, or are breastfeeding and about your detailed medical history.

Dosage

Overdose

Taking Powergesic MR tablet in high doses may result in liver and kidney damage. Other symptoms of overdose include headache, nausea, vomiting, and stomach pain. If you think you have taken too much of this medicine, contact your doctor immediately or visit the nearest hospital.

Missed a Dose

If you have missed taking any dose of Powergesic MR tablet, take it as soon as you remember. If it's time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose of this medicine to compensate for the missed one.

Mode of Action

How Does It Work?

• Powergesic MR tablet works by the combined action of its three components - diclofenac, paracetamol, and chlorzoxazone.
• Diclofenac and paracetamol are non-steroidal anti-inflammatory medicines (NSAIDs). They inhibit the production of prostaglandins, which are responsible for causing pain, swelling, and inflammation.
• Chlorzoxazone is a muscle relaxant that works by blocking the signals of painful sensation through the nerve to the brain. This helps to reduces pain and stiffness.

Directions for Use

• Powergesic MR tablet should be taken as directed by your doctor.
• Swallow it as a whole with a glass of water.
• Do not cut, break, or chew the medicine.
• It would be best if you take it at a fixed time for optimal results.
• Do not consume more than the dose prescribed by your doctor.

Precautions and Warnings

Pregnancy

Can I take Powergesic MR tablet during pregnancy?

It is unsafe to take Powergesic MR tablet during pregnancy. Hence, this medicine should not be taken by pregnant women.

Breast Feeding

Can I take Powergesic MR tablet while breastfeeding?

It is advised not to use Powergesic MR tablet if you are breastfeeding.

Driving

Can I drive if I have consumed Powergesic MR tablet?

Powergesic MR tablet may cause dizziness. If you experience any such effects after taking this medicine that may affect your ability to drive safely, it is suggested to avoid driving.

Alcohol

Can I consume alcohol with Powergesic MR tablet?

It is advised to avoid the consumption of alcohol during treatment with Powergesic MR tablet as it may worsen the side effects.

Other General Warnings

Talk to your doctor if

• You have heart problems like high blood pressure, or heart failure.
• You have kidney or liver problems.
• You are an elderly patient or taking diuretics or have a kidney disorder.
• You are suffering from gastrointestinal problems like bleeding, ulcers in the intestine (perforation), or Crohn's disease or you are passing black tarry stools.
• You have asthma.
• You have systemic lupus erythematosus (an autoimmune disorder).
• You are an alcoholic.
• You have disorders related to blood like clotting problems and anaemia.
• You develop skin rashes and lesions after taking this medicine.

Contraindications

• If you are allergic to diclofenac, paracetamol, chlorzoxazone, or any ingredient of Powergesic MR tablet.
• If you are allergic to other painkillers such as aspirin and have experienced severe asthma, rashes or any other allergy.
• If you have problems with kidney and liver function.
• If you are pregnant or elderly (65 years of age or older).
• If you are experiencing bleeding from the stomach and intestine or have an active peptic ulcer.
• If you are suffering from any heart disease like heart failure and high blood pressure.
• This medicine should not be used for relieving pain before, during, and after bypass surgery of the heart.

Side effects

• Nausea
• Vomiting
• Dizziness
• Weakness

Interactions

Interactions with other medicines

• Some medicines can affect the way Powergesic MR tablet works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
• Tell your doctor about all the medicines, supplements, or herbals you are currently taking or might take to avoid any possible interaction.
• Do not take any other medicines containing paracetamol or diclofenac as there is a risk of liver damage.
• Particular care should be taken if you are taking medicines for treating high blood pressure, heart failure
• Medicines like water pills and medicines used to modify immune response during organ transplants like cyclosporine and tacrolimus can lead to kidney damage when taken along with Powergesic MR tablet.
• This medicine can increase the levels of lithium and methotrexate.
• Increased risk of stomach ulcers or bleeding when taken with steroids or other pain relief medicines like aspirin.
• There is a risk of bleeding if you are taking blood-thinning medicines like warfarin and coumarin.
• Increased risk of fits if you are taking this medicine with antibiotics like levofloxacin and ciprofloxacin.
• If you are taking medicines to treat diabetes, be cautious about symptoms of low glucose levels like sweating, anxiety, fast heartbeat, and hunger pangs.
• Medicines used to treat fits, seizures, and depression like phenobarbital, carbamazepine, phenytoin, and clonazepam should be used with caution as Powergesic MR tablet can increase the side effects of these medicines.
• Medicines used to treat gout like probenecid, medicines used to treat bacterial infections like chloramphenicol, rifampicin, and medicines used to treat HIV infections like zidovudine should be used cautiously.

Storage and disposal

• Powergesic MR tablet should be stored below 30°C away from moisture and heat.
• Keep it away from children and pets.

Frequently Asked Questions (FAQs)

What precautions do I need to take before taking Powergesic MR tablet?

You are supposed to tell the doctor your health condition like if you have diabetes, blood disorders, liver disease or kidney disease. Also inform them about all other medicines, herbal preparations and over the counter products you are taking.

Can I take Powergesic MR tablet for a toothache?

Do not take this medicine without consulting your dentist. The underlying cause of toothache can be different. Therefore, do not self medicate.

How do Powergesic MR tablet tablets work?

Powergesic MR tablet contains Paracetamol, Diclofenac and Chlorzoxazone. Paracetamol and Diclofenac reduce the production of chemicals responsible for inflammation and pain. Chlorzoxazone helps in relaxing the muscles and improves pain and stiffness caused by muscle strains and sprains.

Can I take my regular painkillers along with Powergesic MR tablet?

No, it is not safe to take any other medicines to relieve pain along with this medicine. Concomitant use of painkillers can cause adverse effects like gastrointestinal bleeding and liver damage.

What is Powergesic MR tablet used for?

• Powergesic MR tablet is used for relieving pain and inflammation of muscles, joints, and bones in conditions such as arthritis, spondylitis, and injuries.
• It is also used after operations and surgeries for relieving pain, inflammation, and swelling.

Is Powergesic MR a painkiller?

Yes, Powergesic MR tablet is a painkiller used for relieving pain and inflammation of muscles, joints, and bones in conditions such as arthritis, spondylitis, and injuries.