Syndopa Plus Tablet

Syndopa Plus Tablet is a medication primarily used in the treatment of Parkinson’s disease, a central nervous system disorder that affects movement and coordination. The disease is characterized by symptoms such as tremors, spasms, muscle stiffness, difficulty in walking, and poor balance. These symptoms occur due to low dopamine levels in the brain, as the neurons responsible for producing dopamine gradually die.

Syndopa Plus Tablet contains two active ingredients: Levodopa and Carbidopa . Levodopa, a central nervous system agent, is converted into dopamine in the brain, which helps improve movement and control. Carbidopa, a decarboxylase inhibitor, works by preventing the breakdown of Levodopa in the bloodstream, ensuring that more Levodopa reaches the brain for effectiveness.

This medication should be taken exactly as prescribed by your doctor, and its use should continue as directed. Common side effects include nausea, vomiting, loss of appetite, light-headedness, lowered blood pressure, confusion, and dyskinesia (involuntary muscle movements). These side effects usually resolve over time and do not require medical attention unless they persist or worsen.

If you experience severe or persistent side effects, consult your doctor promptly. It is important to inform your doctor if you are allergic to any components of the medication or have a medical history that includes glaucoma, asthma, dizziness, mental illness, or intense urges such as gambling, overeating, or increased sexual impulses. Additionally, Syndopa Plus should not be taken during pregnancy or breastfeeding without medical advice.

Levodopa must also be discontinued at least 12 hours before starting this medication. Always communicate openly with your doctor about your medical condition and any concerns before beginning Syndopa Plus Tablet. Syndopa CR tablet , Tidomet Plus tablet and LCD tablet are a few other medicines containing levodopa and carbidopa.

Dosage

Overdose

If you happen to take more than the prescribed dose of Syndopa Plus tablet, report to the nearest hospital immediately. It may cause rapid, irregular heartbeats, uncontrolled muscular twitching and loss of consciousness.

Missed a Dose

If you missed any dose of Syndopa Plus tablet, take it as soon as you remember it. If it is almost time for your next dose, skip the missed dose and take the next dose at the scheduled time. Do not take a double dose to compensate for the missed dose.

Mode of Action

How Does It Work?

Syndopa Plus offers relief in symptoms of Parkinson’s disease by increasing the levels of dopamine in the brain. Levodopa gets converted into Dopamine. This dopamine gives relief from symptoms of Parkinson's disease. Carbidopa helps in maintaining an optimal level of levodopa by inhibiting its breakdown by enzymes before it reaches the brain.

Directions for Use

• Take Syndopa Plus tablet as a whole with a sufficient amount of water.
• Try to take it at a fixed time every day as advised by your doctor.
• Do not skip the doses even if you feel better.

Precautions and Warnings

Pregnancy

Can I take Syndopa Plus tablet during pregnancy?

Insufficient data is available regarding Syndopa Plus Tablet's possible side effects on the foetus. Thus, pregnant women or women who are planning to get pregnant must take this medicine on doctor's prescription only.

Breast Feeding

Can I take Syndopa Plus tablet while breastfeeding?

It is not advised to take Syndopa Plus tablet if you are breastfeeding your baby as levodopa passes into breast milk.

Driving

Can I drive if I have consumed Syndopa Plus tablet?

It is not advised to drive or operate heavy machinery if you have taken Syndopa Plus tablet as it makes you dizzy and drowsy and can also affect your balance and movements.

Alcohol

Can I consume alcohol with Syndopa Plus tablet?

You should avoid alcohol consumption while taking Syndopa Plus tablet.

Other General Warnings

Talk to your doctor if

• You experience mood changes, sleep attacks or excessive sleepiness.
• You have a history of fits.
• You have or had an ulcer in your stomach or intestine.
• You have had a heart attack, heart disorder, or breathing problems.
• You have had kidney, liver or hormonal problems.
• You have a due surgery or operation.
• If you have an eye condition called 'glaucoma’, you will need to have regular checks on the pressure in your eye.

Contraindications

• If you are allergic to levodopa, carbidopa or any ingredients of Syndopa Plus tablet.
• If you have a history of skin cancer called melanoma or the presence of moles on the skin, which a doctor has not clinically checked.
• If you are taking medicines for psychiatric health disorders belonging to a class, MOAIs like Rasagiline should be stopped at least 14 days before you start taking this medicine.
• If you have raised pressure in the eyes, it is a condition called narrow-angle Glaucoma.
• If you are diagnosed with any serious psychiatric illness.
• If you are pregnant or planning to get pregnant, or if you are a breastfeeding mother.

Side effects

• Uncontrolled movements
• Headache
• Nausea
• Vomiting
• Dry mouth
• Diarrhoea
• Reduced appetite
• Drowsiness

Interactions

Interactions with other medicines

• Some medicines can affect the way the Syndopa Plus tablet works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
• Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.
• Especially if you are taking any other medicine especially to treat Parkinson’s disease.
• If you are taking any iron preparations, it may decrease the effectiveness of the Syndopa Plus tablet when used concomitantly.
• Medicine for any psychiatric illness may cause worsening of side effects; the dose needs to be adjusted.
• The patient’s response should be monitored when taking Syndopa Plus tablet with anticholinergic preparations like Benzatropine and Procyclidine.
• You may experience low blood pressure on standing suddenly from lying posture if you are on any antihypertensives.
• Medicine for tuberculosis and epilepsy may require a change in dosage.

Interactions with food items

Syndopa Plus can be taken with or without food. However, it is generally better to take it with a small meal or snack to minimize nausea.

Storage and disposal

• Store Syndopa Plus tablet at a temperature below 30°C.
• Keep it out of the reach of children and pets.

Frequently Asked Questions (FAQs)

What diet restrictions should I follow with Syndopa Plus tablet?

You should avoid having heavy meals or a protein-rich diet in large quantities. Avoid taking it with foods like egg, meat, milk or cheese as it may not work properly.

Can Syndopa Plus be taken empty stomach?

It can be taken with or without food. Avoid protein meals as it can delay the action of this medicine.

How Syndopa plus works?

This medicine works by increasing the levels of dopamine which is the main cause of parkinsonism.

Can Syndopa Plus tablet cause dark urine?

Yes, this medicine can turn the colour of your urine, saliva and sweat dark (red, brown or black). This is not harmful and can sometimes also stain your clothes and bedding.

Can we stop Syndopa Plus tablet?

No, do not stop taking Syndopa Plus tablet without consulting your doctor. Sudden stopping of this medicine may cause withdrawal symptoms and your condition might worsen. Hence, you should never stop taking this medicine even if you start feeling better.

What is the composition of Syndopa plus?

The composition of Syndopa plus includes - levodopa and carbidopa, as its active ingredients.

What is the difference between Syndopa plus and Syndopa Cr?

Both the medicines are antiparkinson's medicine having the same active ingredients. The only difference is, Syndopa Cr contains double the strength of ingredients as compared to Syndopa plus.

What is Syndopa Plus used for?

Syndopa Plus tablet is used for the treatment of Parkinson's disease characterized by impaired posture and balance, shakiness, stiffness of muscle and inability to perform basic body movements.

What is the maximum dose of Syndopa Plus?

The dose and frequency of Syndopa Plus vary among individuals depending on the condition it is being taken for. You should not consume more than the recommended daily dose by a doctor.

Can Syndopa Plus tablet cause nausea or vomiting?

Yes, mild nausea or vomiting may occur when starting Syndopa Plus. Taking the tablet with food or as advised by your doctor can help reduce this effect.

Can the Syndopa Plus tablet affect blood pressure?

Some patients may experience low blood pressure or dizziness when standing up quickly. Inform your doctor if you notice fainting, dizziness, or a rapid heartbeat.