Tazact 4.5gm Powder For Injection

Tazact 4.5gm injection contains a combination of piperacillin and tazobactam as active substances. It belongs to the class of penicillin antibiotics.

Tazact 4.5gm injection is used in adults and adolescents to treat bacterial infections of the lower respiratory tract (lungs), urinary tract (kidneys and bladder), abdomen, skin, or blood. It is also used in children aged 2-12 years to treat infections of the abdomen such as appendicitis, peritonitis (infection of the fluid and lining of the abdominal organs), and gallbladder (biliary) infections.

Before using this medicine, inform the doctor if you are pregnant, breastfeeding, and about your detailed medical history. Tazact 4.5gm injection will be given to you by your doctor or nurse.

Do not self-inject this medicine.

Dosage

Overdose

Your doctor or nurse will give Tazact 4.5gm injection, and hence, the chances of an overdose are unlikely. However, if you experience loose motions, nausea, or vomiting after taking this injection, inform your doctor as soon as possible.

Missed a Dose

If you think your doctor or nurse might have missed a dose of Tazact 4.5gm injection, then inform them.

Mode of Action

How Does It Work?

• Tazact 4.5gm injection contains a combination of piperacillin and tazobactam as active substances.
• Piperacillin binds to certain proteins in the bacteria called penicillin-binding proteins that are required for the proper development of the bacterial cell wall. This causes the formation of defective cell walls in the bacteria which leads to bacterial death. However, bacteria make an enzyme called beta-lactamase which can destroy piperacillin.
• Tazobactam inactivates this enzyme and helps piperacillin to function optimally.

Directions for Use

• Tazact 4.5gm injection will be given in a hospital by your doctor or nurse as an injection.
• Do not self-inject this medicine. Follow any aftercare instructions suggested by the doctor or nurse.

Precautions and Warnings

Pregnancy

Can I take Tazact 4.5gm injection during pregnancy?

• It is advisable not to take Tazact 4.5gm injection during pregnancy. However, this medicine can be given to you by your doctor if required after assessing the benefits over risks. Consult your doctor if you are pregnant, think you may be pregnant, or are planning to have a baby.

Breast Feeding

Can I take Tazact 4.5gm injection while breastfeeding?

Tazact 4.5gm injection may into human breast milk. Consult your doctor if you are breastfeeding. Your doctor will tell you about the use of this medicine after assessing the benefits over risks.

Driving

Can I drive if I have taken Tazact 4.5gm injection?

No information is available on the effect of Tazact 4.5gm injection on the ability to drive. If you experience any symptoms after taking this medicine that may affect your ability to drive properly, it is suggested that you avoid driving.

Alcohol

Can I consume alcohol with Tazact 4.5gm injection?

No information is available on the interaction of Tazact 4.5gm injection with alcohol. Ask your doctor for advice on the use of alcohol with this medicine.

Other General Warnings

Talk to your doctor if

• You have a history of allergic reactions to penicillins, cephalosporins, or carbapenems.
• You develop skin disorders like painful rashes along with flu after using this medicine.
• You have diarrhea and pus in your stool after taking this medicine.
• You experience bleeding disorders or are taking blood-thinning medicines like warfarin.
• You experience fits or convulsions.
• You have problems with kidney function.
• You have weakness, fatigue, muscle cramps, or low levels of potassium.

Contraindications

• If you are allergic to piperacillin, tazobactam, or any of the ingredients of Tazact 4.5gm injection.
• If you have a history of allergic reactions to any other antibiotics like cephalosporins, monobactam, or carbapenem.

Side effects

• Diarrhoea
• Nausea
• Vomiting
• Headache
• Rashes

Interactions

Interactions with other medicines

• Some medicines can affect the way Tazact 4.5gm injection works, or this medicine itself may reduce the effectiveness of other medicines taken at the same time.
• Tell your doctor about all medicines, supplements, or herbals you are currently taking or might take to avoid any possible interaction.
• Particular care should be taken if you are taking medicines to relax the muscles during surgery like vecuronium, to stop blood clotting like warfarin, to treat certain types of cancers like methotrexate, to treat gout like probenecid.
• Care should be taken if you have kidney problems and you are taking antibiotics like tobramycin, gentamicin, and vancomycin.

Storage and disposal

• Store Tazact 4.5gm injection at or below 25°C protected from light.
• Keep it out of the reach of children and pets.

Frequently Asked Questions (FAQs)

I am suffering from flu-like common cold, can I take Tazact 4.5gm injection?

No, Tazact 4.5gm injection is for treating severe infections caused by bacteria and not viral infections. This medicine should only be taken when prescribed by the doctor.

I am on a restricted salt diet, can I take Tazact 4.5gm injection?

• No, as this medicine contains an ample amount of sodium, it is advisable to be very cautious and discuss your dietary restrictions with your doctor before taking this medicine.

What is the use of Tazact 4.5gm injection?

• Tazact 4.5gm injection is used in adults and adolescents for the treatment of complicated bacterial infections of the stomach, abdomen, skin, soft tissue, diabetic foot infections due to diabetes and pneumonia.
• It is also used in children aged 2-12 years for the treatment of infections of the abdomen such as appendicitis, peritonitis (infection of the fluid and lining of the abdominal organs) and gallbladder (biliary) infections.

Can Tazact 4.5gm injection be used in children?

Yes, Tazact 4.5gm injection can be used in children from 2 to 12 years of age for the treatment of various bacterial infections. However, this medicine will be given to your child in a hospital setting by the doctor or nurse. Do not self-inject this medicine.