Tazar 4.5 Powder for injection

Tazar 4.5 gm injection contains a combination of piperacillin sodium and tazobactam sodium. It belongs to the class of penicillin antibiotics and is effective against various bacterial infections of the respiratory tract, stomach and skin.

You may experience nausea, vomiting, diarrhoea along with pain and rash at the site of injection after taking inj Tazar. Individuals suffering from liver or kidney disorders must use this medicine with caution. Please consult your doctor about your medical condition before using it.

Dosage

Overdose

Your doctor or nurse will give Inj Tazar . Therefore, it is less likely to provide you with more or less of this medicine. However, if you experience loose motions, nausea, vomiting and fits immediately after taking this injection, inform your doctor as soon as possible.

Missed a Dose

You will be monitored by your doctor or nurse on when the injection should be given to you. It is unlikely that you will be missing any dose. However, if you think your doctor or nurse might have missed a dose, inform them. It is advisable not to miss any dose of antibiotics as it can result in failure of the therapy.

Mode of Action

How Does It Work?

Tazar 4.5 gm injection acts by killing the bacteria responsible for infections. However, bacteria make an enzyme (beta-lactamases) which can destroy Piperacillin. Tazobactam inactivates this enzyme and hence helps Piperacillin to function optimally.

Directions for Use

Inj Tazar will be given in a hospital by your doctor or nurse as an injection. Do not self-inject this medicine.

Precautions and Warnings

Pregnancy

Can I take the Tazar 4.5 gm injection during pregnancy?

It is advisable not to take Inj Tazar during pregnancy as it passes the placental barrier. However, it can be given to you by your doctor if required after assessing the benefits over risks. Consult your doctor if you are pregnant, think you may be pregnant or are planning to have a baby.

Breast Feeding

Can I take the Tazar 4.5 gm injection while breastfeeding?

The components of inj Tazar pass into the breastmilk and are known to cause fungal infections of the mouth and diarrhoea in babies. Consult your doctor if you are breastfeeding, your doctor will tell you about the use of this injection after assessing the benefits over risks.

Driving

Can I drive if I have taken the Tazar 4.5 gm injection?

No information is available on the effect of this medicine on the ability to drive or use machines. However, if you experience any side effects after taking this medicine, do not drive.

Alcohol

Can I consume alcohol with the Tazar 4.5 gm injection?

No information is available on the interactions of this medicine with alcohol. However, consuming alcohol may exaggerate the side effects of this medicine. Thus, it is advisable not to consume alcohol when you are taking this medicine.

Other General Warnings

Talk to your doctor if

• You have a history of allergic reactions to Penicillin, Cephalosporins, Carbapenems.
• You develop serious skin disorders like painful rashes along with flu.
• You have diarrhoea and pus in your stool after taking this medicine, immediately stop the medicine and report to your doctor.
• You experience bleeding disorders or taking blood-thinning medicines like Warfarin.
• You experience fits or convulsions.
• You have problems with kidney function.
• You have weakness, fatigue, muscle cramps or low levels of potassium.

Contraindications

• If you are allergic to Piperacillin and Tazobactam or any other ingredients of inj Tazar.
• If you have a history of severe allergic reactions to any other antibiotic like Cephalosporins, Monobactam and Carbapenem.

Side effects

• Diarrhoea
• Constipation
• Nausea
• Vomiting
• Indigestion
• Stomach pain
• Fever
• Anaemia
• Fungal infection (candidiasis)
• Headache
• Sleeplessness
• Rashes
• Itching
• Inflammation and swelling at the injection site.

Interactions

Interactions with other medicines

• Medicines used to relax the muscles during surgery like Vecuronium.
• Close monitoring of blood function is required if you are on medicines used to stop blood clotting like Warfarin.
• Medicines used to treat certain types of cancers like methotrexate.
• Medicines used to treat gout-like probenecid.
• If you have kidney problems and you are taking antibiotics like Tobramycin, Gentamicin and Vancomycin.

Storage and disposal

• Store this medicine at or below 25°C.
• Protect it from light.
• Keep it out of the reach of children and pets.
• Any unused portion should not be stored and discard it properly.

Frequently Asked Questions (FAQs)

I am suffering from the flu-like common cold, can I take inj Tazar?

No, inj Tazar is for treating severe infections caused by bacteria and not viral infections. This medicine should only be taken when it is prescribed by the doctor.

I am on a restricted salt diet, can I take inj Tazar?

No, as this injection contains an ample amount of sodium, it is advisable to be very cautious and discuss your dietary restrictions with your doctor before taking this medicine.

Who should not take the Tazar 4.5gm injection?

Tazar 4.5 gm injection is not recommended for individuals suffering from liver and kidney disease, those who are allergic to active ingredients like antibiotic like Cephalosporins, Monobactam and Carbapenem.

What happens if I am administered a higher dose of this injection accidentally?

As this injection will be administered to you by your doctor nurse an overdose is a rare scenario. Nonetheless, if you are administered an overdose you may experience loose motions, nausea, vomiting and fits. Inform this immediately to your doctor.

Can Tazar injection be used in covid?

No. You should not take any medicine to treat or prevent covid-19 without consulting a doctor. If you have been tested positive with covid-19 immediately inform your doctor. Moreover, this injection will be given by a doctor or nurse in a hospital/clinic based on the severity of the underlying condition and medical history.

What is the composition of Tazar 4.5?

The composition of Tazar 4.5 consists of a combination of piperacillin sodium and tazobactam sodium, as its active component.

How do you use Tazar injection?

Tazar injection will be given in a hospital by your doctor or nurse as an injection. Do not self-inject this medicine.

What is the mechanism of action of Tazar injection?

Tazar 4.5 gm injection acts by killing the bacteria responsible for infections. However, bacteria make an enzyme (beta-lactamases) that can destroy Piperacillin. Tazobactam inactivates this enzyme and hence helps Piperacillin to function optimally.