Tisto MH Cream

Tisto Mh Cream is a combination medicine used in the treatment and prevention of moderate-to-severe melasma (dark and discoloured patches on the skin) to lighten the skin tone or appearance and senile lentigines (dark spots or age spots in older people due to exposure to the sun). It contains mometasone, tretinoin and hydroquinone. Avoid sun exposure immediately after applying for this medicine.

Use this medicine exactly as instructed by the doctor.

Dosage

Overdose

As Tisto Mh Cream is for external application only, cases of overdose are unlikely. However, upon accidental ingestion, contact your doctor immediately or visit the nearest hospital. If you have overapplied it, then wipe out the excess medicine with tissue or cotton. Excessive use for a prolonged duration is not advisable as it can lead to hormonal issues.

Missed a Dose

If you have missed the application of Tisto Mh Cream, then apply it as soon as possible. Do not overapply this Cream to compensate for the missed application.

Mode of Action

How Does It Work?

• Tisto Mh Cream contains a combination of Mometasone, Tretinoin and Hydroquinone as active ingredients and works by the combined action of these three components.
• Hydroquinone inhibits an enzyme known as tyrosinase, which is responsible for the production of a pigment called melanin. Melanin is responsible for skin pigmentation and melasma.
• Tretinoin is a metabolite of vitamin A. It is responsible for the elimination of melanin that has been formed. It also has anti-inflammatory properties.
• Mometasone is a corticosteroid and it works by blocking the production of inflammatory chemicals like prostaglandins and leukotrienes. Mometasone narrows and constricts blood vessels, which are dilated (widened) and leaky and allowing other inflammatory cells into the skin to promote the inflammatory response.

Directions for Use

• Use Tisto Mh Cream as directed by your doctor.
• Apply it on a healthy skin surface. Avoid applying on cuts and wounds.
• Wash your hands before and after using this medicine unless your hands are the area to be treated.
• If your eyes come in contact with this Cream, then rinse your eyes with clean water immediately.

Precautions and Warnings

Pregnancy

Can I apply Tisto Mh Cream during pregnancy?

Since there is limited safety data available, Tisto Mh Cream should only be used if recommended by the doctor. In case it is prescribed to you, avoid using it in larger skin areas for a prolonged duration.

Breast Feeding

Can I apply Tisto Mh Cream while breastfeeding?

It is unknown if the components of Tisto Mh Cream pass in breast milk and there are no establishments of its safety in breastfeeding women. Thus, it is not recommended to use if you are breastfeeding.

Driving

Can I drive if I have applied Tisto Mh Cream?

Tisto Mh Cream is a topical preparation and may not affect your driving ability or ability to handle machinery.

Alcohol

Can I consume alcohol with Tisto Mh Cream?

It is unknown if components of Tisto Mh Cream interact with alcohol.

Other General Warnings

Talk to your doctor if

• You have a history of allergic reactions after the application of topical Creams.
• You are pregnant or breastfeeding.
• You think rashes or infections have developed on the skin after using this medicine.
• A prolonged application may lead to side effects such as Cushing's syndrome (weight gain, fatty deposits under the skin, moon face, purple patches on the skin), increased sugar levels in the blood and urine.
• Avoid exposure to sun rays as it may be harmful after applying this Cream.

Contraindications

• If you are allergic to mometasone, tretinoin and hydroquinone or any other ingredients of Tisto Mh Cream.
• If you have skin conditions such as eczema (infected skin due to allergy), rosacea (small red pustules on face), rashes around the mouth (perioral dermatitis) or damaged skin anywhere in the body.
• If you have a viral or fungal infection of the skin, any ulcers on the skin or tuberculosis.
• If you need exposure to the sun for prolonged periods (using sunscreen lotion is advisable).
• If you have a skin tumour or a family history of skin tumour.

Side effects

• Itching, redness, burning, irritation and thinning of the skin.
• Skin sensitivity at the site of application.

Interactions

Interactions with other medicines

• Since Tisto Mh Cream is to be used externally on the skin, it is less likely to interact with other medicines. However, always consult your doctor if you are taking other medicines for treating other health conditions.
• You should always tell the doctor if you are taking any other medicines, herbal preparation and supplements to avoid interaction with Tisto Mh Cream.

Storage and disposal

• Store Tisto Mh Cream in the original container in a clean and dry place, protected from moisture, sunlight and heat.
• Keep the medicine away from children and pets.
• Do not freeze.

Frequently Asked Questions (FAQs)

How should I use Tisto Mh Cream?

• Apply it gently as a thin film and rub or massage it thoroughly after applying until the Cream absorbs into the skin.
• Exposure to the sun should be avoided and use a broad-spectrum sunscreen to prevent the sun's radiation from reaching your skin.
• Do not use this Cream more than as advised by the doctor. This Cream should not be used for a prolonged duration to avoid side effects such as skin thinning, irritation, etc.

What are the precautions to be taken while applying Tisto Mh Cream?

• Do not apply anywhere near the eyes, nose, mouth or any infected or exposed surfaces.
• Do not occlude (applying a polythene film) after applying this Cream or use it under bandages.
• Limit sun exposure and use a broad-spectrum sunscreen while going out in the sun to avoid damage to the skin by radiations.
• You should cover the areas of skin where this medicine is applied when outdoors.

What is melasma?

Melasma is a skin condition characterised by dark spots or pigmentation (excessive production of melanin) on the skin. It appears as greyish brown to brown patches on the face. It usually occurs on the face, involving cheeks, forehead, lower eyelids, uppers lip and nose.

What are the causes of melasma?

The exact cause of melasma is not known. Pregnancy, birth control pills, hormonal changes, exposure to sunlight (UV rays), hypothyroidism or a family history of melasma are believed to be some common triggers for melasma.