Tolvasca 30mg Tablet

Tolvasca Tablet contains Tolvaptan as its active ingredient. It is used for the treatment of low sodium levels in the blood seen in conditions such as heart disease, liver disease (liver cirrhosis), etc. where a decrease in fluid intake fails to increase sodium level in blood.

Tolvasca works by blocking the action of vasopressin hormone which is also known as an antidiuretic hormone on the kidney. This results in failure of water absorption by the kidney leading to an increase in urine production, decreasing water content in the blood and thereby increasing sodium level in the blood. Headache, dizziness, excessive thirst, loose motions, dry mouth, etc.

are some of the side effects of using this medicine. This medicine can be taken with or without food.

Dosage

Overdose

• Symptoms of overdose include increased frequency of urination, feeling thirsty, dehydration, etc.
• If you have taken too much of this medicine then contact your doctor or reach out to the nearest hospital immediately.

Missed a Dose

If you have missed taking any dose of Tolvasca Tablet then take it as soon as you remember. If it's already time for the next dose then skip the missed dose and follow the regular dosing schedule.

Mode of Action

How Does It Work?

Tolvasca Tablet works by blocking the action of vasopressin hormone which is also known as an antidiuretic hormone in the kidney. This results in failure of water absorption by the kidney leading to an increase in urine production, decreasing water content in the blood and thereby increasing sodium level in the blood.

Directions for Use

Take Tolvasca Tablet as directed by the physician. Swallow it whole with a glass of water. It can be taken with or without food. Do not break, crush or chew the medicine. It is essential to take it regularly and at a fixed time. Do not exceed the dose more than the recommended amount.

Precautions and Warnings

Pregnancy

Can I take Tolvasca Tablet during pregnancy?

Components of Tolvasca are known to be harmful to the foetus, thus it should be avoided in pregnant women. If you become pregnant while on the treatment with this medicine immediately inform your doctor.

Breast Feeding

Can I take Tolvasca Tablet while breastfeeding?

Components of this medicine are known to be excreted in the milk. This medicine should be avoided if you are breastfeeding.

Driving

Can I drive if I have consumed Tolvasca Tablet?

This medicine can cause dizziness, weakness or tiredness. Avoid driving while on this medicine.

Alcohol

Can I consume alcohol with Tolvasca Tablet?

Alcohol is not known to interact with this medicine. However, if you consume alcohol too often discuss it with your doctor.

Other General Warnings

Talk to your doctor if

• You have any liver disease or you are diabetic.
• You have difficulty in urination.
• Your blood sodium levels are too high or low.
• You have high levels of uric acids in the blood.
• You are suffering from any kidney disease.
• Use of Tolvasca Tablet may cause your liver to not function properly, if you find dark urine, nausea or vomiting after using this medicine then immediately inform your doctor.
• This medicine causes loss of water from the body, it is important to drink plenty of water during the treatment.
• Tolvasca Tablet should not be given to the children below the age of 18 years.

Contraindications

• If you are allergic to Tolvaptan or any of the other ingredients of Tolvasca Tablet.
• If your urine output in a day is less than 100ml.
• If your doctor tells you that you have a liver injury after doing a blood investigation for liver function.
• If your doctor tells you that you have a high sodium level in your blood.
• If you are a pregnant or lactating mother.
• If you have severe dehydration.

Side effects

• Headache
• Dizziness
• Excessive thirst
• Loose motions
• Dry mouth
• Increased frequency of urination
• Excessive urination at night
• Tiredness
• Dehydration
• Sleeplessness

Interactions

Interactions with other medicines

• Concomitant use of Tolvasca Tablet with other medicines such as amprenavir, aprepitant, ciprofloxacin, diltiazem, fluconazole, imatinib, verapamil, itraconazole, clarithromycin causes increases its action.
• Medicines such as rifabutin, phenytoin, rifampicin, carbamazepine, when taken together with Tolvasca Tablet, can decrease the effectiveness of this medicine.
• Concomitant use of Tolvasca Tablet along with other medicines such as hypertonic saline solution cause an increase in sodium level in blood.
• Medicines used in for the removal of water from the body (diuretics) such as thiazide and loop diuretic can cause severe dehydration.
• Taking this medicine along with other medications such as desmopressin decreases the action of desmopressin.
• Discuss with your doctor about any other medicine, herbal preparation and supplements you are taking currently to avoid any possible drug interactions.

Interactions with food items

Taking Tolvasca Tablet with grapefruit juice increases the blood level of this medicine. grapefruit should be avoided when taking this medicine.

Storage and disposal

• Store at room temperature in a cool and dry place. Store in the original package.
• Keep it out of the reach of children and pets.

Frequently Asked Questions (FAQs)

What is the use of Tolvasca Tablet?

Tolvasca Tablet is used for the treatment of low sodium level in the blood seen in conditions such as heart disease, liver disease (liver cirrhosis), etc. where a decrease in fluid intake failed to increase sodium level in blood.

How does Tolvasca Tablet work?

Tolvasca Tablet works by blocking the action of vasopressin hormone which is also known as an antidiuretic hormone on the kidney. This results in failure of water absorption by the kidney leading to an increase in urine production, decreasing water content in the blood and thereby increasing sodium level in the blood.

Can Tolvasca Tablet cause diarrhoea?

Tolvasca Tablet can cause diarrhoea as a side effect of using this medicine.