Ujvira 100mg Dry Vial Of 1 Powder For Injection

Ujvira powder for injection contains trastuzumab emtansine, a prescription medication for treating HER2-positive breast cancer. This drug combines trastuzumab, an antibody targeting HER2 receptors, with emtansine, a chemotherapy agent that destroys cancer cells. Ujvira powder for injection is indicated for both early and advanced stages of breast cancer, particularly in cases where the disease recurs within six months following chemotherapy.

Ujvira powder for injection may cause side effects like nausea, vomiting, diarrhoea, and hair loss. Tell your doctor right away if you experience any allergic reactions or unusual bleeding. Ujvira powder for injection typically does not harm your kidneys.

In rare cases, you might react to the infusion. Always talk to your healthcare provider for personalized medical advice.

Dosage

Overdose

Your doctor or nurse will give Ujvira powder for injection. Therefore, the chances of overdose are very rare. If you experience symptoms immediately after taking the injection, seek medical help.

Missed a Dose

Your doctor or nurse will carefully monitor and schedule your injections, making it unlikely that a dose will be missed. However, if you suspect a dose might have been overlooked, let them know immediately.

Mode of Action

How Does It Work?

Trastuzumab emtansine is a targeted therapy for HER2-positive breast cancer. It combines an antibody (trastuzumab) that binds to the HER2 protein on cancer cells with a chemotherapy drug (emtansine). This allows the chemotherapy to be delivered directly to the cancer cells, potentially reducing side effects while effectively targeting and killing the tumour.

Directions for Use

Ujvira powder for injection will be given to you in the hospital by your doctor or nurse. Follow any instructions suggested by the doctor or nurse during the procedure or for aftercare.

Precautions and Warnings

Pregnancy

Can I take Ujvira powder for injection during pregnancy?

Ujvira powder for injection should be avoided in pregnancy and during treatment with this injection, and after 7 months after treatment has ended, it is advised to use an effective method of contraception.

Breast Feeding

Can I take Ujvira powder for injection while breastfeeding?

Ujvira powder for injection can pass into breast milk, which could harm a breastfeeding baby. Therefore, it's strongly recommended to avoid breastfeeding during Ujvira powder for injection treatment and for 7 months after the last dose of the medication.

Driving

Can I drive if I have taken Ujvira powder for injection?

Ujvira powder for injection treatment may affect your ability to drive or operate machinery. If you experience side effects like dizziness, sleepiness, chills, or fever during treatment, avoiding driving or operating machinery is crucial until these symptoms subside.

Alcohol

Can I consume alcohol with Ujvira powder for injection?

No known interactions with alcohol.

Other General Warnings

Talk to your doctor if

• You have kidney disease, have undergone a kidney transplant, or have any history of liver disease.
• You are taking anticoagulants or antiplatelet medicines, such as warfarin or heparin.
• You have a history of thrombocytopenia (low platelet count) or are experiencing any signs of unusual bleeding or bruising.
• You have or have had heart conditions such as congestive heart failure, arrhythmias, or a history of myocardial infarction.
• You have a low left ventricular ejection fraction (LVEF) or heart-related symptoms, such as shortness of breath or chest pain.
• You are experiencing symptoms of peripheral neuropathy, such as numbness, tingling, or weakness in your extremities.
• You have experienced any infusion-related reactions or severe allergic reactions to trastuzumab or similar medicines in the past.
• You have a history of lung disease, interstitial lung disease, or pneumonitis.
• You are experiencing symptoms like persistent cough, fatigue, or difficulty breathing.
• You are undergoing or planning to undergo concurrent radiation therapy.
• You are pregnant, planning to become pregnant, or breastfeeding.
• You have any signs of liver dysfunction, such as yellowing of the skin or eyes, dark urine, or unusual fatigue.
• You are on any other medications or supplements, including herbal products, that could interact with trastuzumab emtansine.
• You have a history of hypersensitivity or anaphylactic reactions to medications.
• You experience any injection-site reactions, including pain, redness, or swelling during or after administration.

Contraindications

If you are allergic to trastuzumab emtansine or any of the other ingredients of Ujvira powder for injection.

Side effects

• Thrombocytopenia
• Anaemia
• Peripheral neuropathy
• Headache
• Epistaxis (nosebleed)
• Cough
• Dyspnoea
• Stomatitis
• Diarrhoea
• Vomiting
• Nausea
• Constipation
• Dry mouth
• Abdominal pain
• Rash
• Pruritus
• Alopecia
• Nail disorder
• Musculoskeletal pain
• Arthralgia
• Myalgia
• Fatigue
• Pyrexia
• Asthenia

Interactions

Interactions with other medicines

Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.

Storage and disposal

Store in a refrigerator (2 °C – 8 °C). Keep the container in the outer carton to protect it from light.