Zyloric 300 Tablet

Zyloric 300 tablets are used to treat and prevent gout and high uric acid levels caused by kidney problems or certain medications. Zyloric 300 tablets contain the active ingredient allopurinol, which reduces uric acid production in the body. Gout is a type of arthritis that causes sudden pain, redness and swelling in the joints.

This is usually caused by uric acid deposits in the joints. You should not take Zyloric 300 tablets if you have kidney or liver disease, are pregnant or breastfeeding or are allergic to allopurinol. Do not recommend Zyloric 300 tablets to anyone else, even if they have similar symptoms to you.

Before taking Zyloric 300 tablets, tell your doctor about all the medications and herbal supplements you are taking and any medical conditions you have.

Dosage

Overdose

Symptoms of an overdose may cause gastrointestinal disturbances like nausea, vomiting, stomach pain, diarrhoea and constipation. In case of an overdose, consult your doctor immediately.

Missed a Dose

If you have missed a dosage of Zyloric 300 tablet, take it as soon as you remember. Skip the missed dose if it is almost time for the next dose. A double dose should not be taken to compensate for the missed one.

Mode of Action

How Does It Work?

Allopurinol present in Zyloric 300 tablet inhibits the action of an enzyme Xanthine oxidase. Xanthine oxidase is an enzyme that plays a crucial role in the synthesis of uric acid in the body. Hence, Allopurinol inhibits the production of uric acid and reduces its levels in blood and urine.

Directions for Use

Take Zyloric 300 tablet with a glass of water. It should be taken with or after meals. Swallow it as a whole. Do not break, cut or chew the tablet. Take it as directed by your doctor and do not consume it more than the prescribed dose.

Precautions and Warnings

Pregnancy

Can I take Zyloric 300 tablet during pregnancy?

Zyloric 300 tablet may cause birth abnormalities. Hence, it should not be used in pregnant women. Consult your doctor before starting any medicine during pregnancy.

Breast Feeding

Can I take Zyloric 300 tablet while breastfeeding?

Allopurinol passes into the breastmilk and may cause side effects to the baby. Hence, Zyloric 300 tablet should not be used by lactating women.

Driving

Can I drive if I have consumed Zyloric 300 tablet?

You may experience side effects like drowsiness or dizziness after taking Zyloric 300 tablets. Be cautious while driving if you experience any side effects.

Alcohol

Can I consume alcohol with Zyloric 300 tablet?

Alcohol increases uric acid levels in the blood and thus increases attacks of Gout. Therefore, avoid alcohol if you have high uric acid levels.

Other General Warnings

Talk to your doctor if

• You experience a severe allergic reaction to the skin after taking this medicine (Ulcersin mouth, nose, genitals, rashes and conjunctivitis).
• You have a liver or kidney function problem.
• You have high blood pressure or heart problems.
• You have a malignancy due to which your body is producing extra urate crystals.
• You may develop a condition called xanthine deposition after using this medicine. However, this can be reduced by maintaining proper hydration.
• Zyloric 300 tablets can dissolve larger uric acid crystals and can cause impaction in the ureter.
• Your TSH hormone levels may go high after using Zyloric 300 tablet.

Contraindications

• If you are allergic to allopurinol or any components of this medicine.
• If you have liver or kidney function problems or heart failure.
• If you are pregnant or are breastfeeding.

Side effects

• An upset stomach
• Diarrhoea
• Drowsiness
• Rashes
• Vomiting
• Nausea
• Allergies
• Increased thyroid hormone level (TSH)

Interactions

Interactions with other medicines

• Sometimes Zyloric 300 tablet may affect the way other medicines work and other medicines may affect how Zyloric 300 tablet works, if taken at the same time.
• Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interactions.
• Especially, if you are taking antibiotics such as Ampicillin or Amoxicillin, Anticancer medicines such as Cyclophosphamide, Anti-hypertensive medicines like Captopril, anti-epileptic medicines like phenytoin.
• Other medicines which are to be used with caution are medicines used for breathing problems like theophylline and immunosuppressants like Cyclosporin.
• Vidarabine, an antiviral medicine can lead to toxic side effects if taken along and therefore, close monitoring is required.
• Other anti-gout medicines like probenecid can alter the effect of Zyloric 300 tablet.

Storage and disposal

• Zyloric 300 tablet should be stored at room temperature away from heat and moisture.
• Keep it out of the reach of children and pets.
• Do not keep any outdated medicines.

Frequently Asked Questions (FAQs)

For how long can I take Zyloric 300 tablet?

The duration of treatment with Zyloric 300 tablet depends on the underlying condition and the patient's response to the treatment.

Can I stop Zyloric 300 tablet if I do not have symptoms?

Do not stop Zyloric 300 tablet without your doctor's recommendation as it may worsen your gout attacks.

What is Gout?

When the uric acid levels increase in the blood, needle-shaped crystals are built-in and around the joint and cause swelling and pain in the joints, which can last for weeks. This condition is known as Gout.

What are the causes of high uric acid levels?

There are several causes of increased uric acid crystals such as heredity, diuretic medicines, chronic alcoholism, hypothyroidism, certain chemotherapy medicines, kidney stones and consumption of food rich in a component called prunes (red meat, organ meat and certain seafood).

What are the general precautions to be taken while using Zyloric 300 tablet?

An adequate intake of water is recommended while using Zyloric 300 tablet. In the case of patients with kidney stones, special care should be taken as the stones may enter the urinary tract.

Zyloric 300 tablet vs Febuxostat, which is a better medicine for gout?

Zyloric 300 tablet contains Allopurinol and is used for the treatment of gout and high levels of uric acid. Febuxostat is also used to treat gout and is generally recommended to patients who cannot take Allopurinol. Based on the cause of your illness, your doctor will prescribe one of these medicines. Do not self-medicate.

Can I take Zyloric without food?

Zyloric should be taken with water, ideally after food or as told by the doctor. It can be taken at any time of the day. However, try to take your medicine at the same time daily.

What are the side effects of Zyloric 300?

Nausea, vomiting, rashes and drowsiness are a few common side effects that can be observed during the treatment with Zyloric 300, although not everyone gets them. Side effects often improve as your body gets used to the medicine.