Ranidom-RD Tablet

Ranidom RD tablet contains esomeprazole and domperidone as its active ingredients. It is an anti-reflux medicine used to treat gastroesophageal reflux disease (GERD) which does not respond to esomeprazole medication alone. GERD is a condition in which acid from the stomach comes back up to the food pipe and causes heartburn, belching, nausea and chest pain.

Ranidom RD works by decreasing the amount of acid produced in the stomach and improving the motility in the gut. Thus, it reduces the backflow of stomach content to the food pipe. Take Ranidom RD as per the prescribed duration.

This tablet should be taken at least an hour before the meal. Do not stop taking Ranidom RD tablet without informing your doctor. This medicine is not recommended for use in patients below 18 years old.

Dosage

Overdose

The symptoms of overdose include nausea, vomiting, indigestion, diarrhoea, constipation, weakness, confusion, agitation, anxiety, fits, altered consciousness, sleepiness, etc. In case of an overdose, contact your doctor immediately or visit the nearest hospital.

Missed a Dose

If you miss any dose of this medicine, take it as soon as you remember it. If it's time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose of this medicine to compensate for the missed one. Skipping doses or not finishing the full course of therapy may reduce the effectiveness of the treatment.

Mode of Action

How Does It Work?

• A pump called the proton pump in the stomach is responsible for the flow of stomach acids. Esomeprazole works by binding to this proton pump in stomach cells and blocks the acid secretion.
• Domperidone acts by increasing the motility of the stomach and intestines so that acid does not reflux back into the food pipe.

Directions for Use

Ranidom RD should be taken at least 1 hour before meals. These tablets should be swallowed whole with water. You should take this medicine regularly at a fixed time and as directed by your doctor. Do not consume it more than the prescribed dose.

Precautions and Warnings

Pregnancy

Can I take Ranidom RD tablet during pregnancy?

Ranidom RD tablet should not be used during pregnancy as there is limited information about its safety in human pregnancy. Consult your doctor if you are pregnant or think you may be pregnant or planning to have a baby.

Breast Feeding

Can I take Ranidom RD tablet while breastfeeding?

Ranidom RD tablet passes into breast milk in small amounts and might affect your baby. Consult your doctor if you are breastfeeding, after assessing the benefits over the risks. Your doctor might change the medicine, ask you to stop breastfeeding or closely monitor the baby.

Driving

Can I drive if I have consumed Ranidom RD tablet?

Ranidom RD tablet may make you feel dizzy, sleepy or even blur your vision on a temporary basis. You should avoid driving if you do not feel well or are unable to be alert.

Alcohol

Can I consume alcohol with Ranidom RD tablet?

You should avoid consuming alcohol while on treatment with this medicine as it is known to increase acidity and can make your acidity worse.

Other General Warnings

Talk to your doctor if

• You have any liver and kidney-related diseases.
• You have a specific blood test (Chromogranin A).
• You experience black stools or have a stomach tumour.
• You have a history of fractures or have osteoporosis or taking steroids.
• You develop skin lesions, especially in the sun-exposed area after taking this medicine.
• You are taking medicines to treat HIV or apomorphine (used to treat muscle stiffness).
• You have heart problems and associated symptoms like palpitations, difficulty in breathing and unconsciousness.
• You experience stomach pain or indigestion, unexplained weight loss, have problems while swallowing, vomit out food or blood after taking this medicine.
• You have low levels of vitamin B12. This medicine is known to reduce the absorption of vitamin B12 after long term use. Supplements may be needed.
• You are on these capsules for long-term treatment (more than three months), your blood magnesium levels may decrease. Hence, your doctor may perform regular tests for the same.
• This medicine is not recommended for patients below the age of 18 years.
• Taking this medicine for more than one year may increase the chances of developing bone fractures.
• This medicine may lead to a slightly increased risk of bacterial infections due to Salmonella and Campylobacter.

Contraindications

• If you are allergic to esomeprazole or domperidone or any other ingredients of Ranidom RD tablet.
• If you have a blockage or tear in the intestines.
• If you are suffering from liver or kidney disorder.
• If you are suffering from bleeding in the digestive system.
• If you have any tumour of the pituitary gland (Prolactin pituitary tumours).
• If you have severe heart problems such as congestive heart failure, heart rhythm problems and electrolyte imbalance.
• If you are taking any medicine which might affect the contraction of the heart muscle (QT prolongation).
• If you are taking medicines such as nelfinavir (anti-HIV medicine), clarithromycin (antibiotic), ketoconazole (antifungal) or verapamil (used in high blood pressure and chest pain).

Side effects

• Headache
• Dizziness
• Nausea
• Vomiting
• Stomach pain
• Gas
• Diarrhoea
• Weakness
• Drowsiness

Interactions

Interactions with other medicines

• Ranidom RD tablet should not be taken concomitantly along with medicines such as nelfinavir (anti-HIV), amiodarone (used to treat muscle stiffness), clarithromycin (antibiotic), ketoconazole (antifungal) or verapamil (used in high blood pressure and chest pain).
• This medicine should also not be taken along with medicines used to treat heart problems (quinidine, sotalol), psychiatric illness (haloperidol, citalopram), antifungals (pentamidine), antimalarials (halofantrine, lumefantrine), medicines used to treat allergies (mizolastine), medicines to treat cancer (toremifene, vandetanib), gastric emptying medicines (cisapride) and other medicines like diphemanil and methadone.
• Concomitant use of this capsule with medicines used to treat psychiatric illness (diazepam), used to treat fits (phenytoin) is not recommended as it may increase the side effects of the medicines.
• Medicine used to treat heart failure like digoxin may lead to toxicity when taken with this medicine.
• If you are taking warfarin (blood-thinner) along with this medicine, caution is needed as there are chances of increased bleeding.
• Other medicines like rifampicin, methotrexate, tacrolimus, voriconazole, cilostazol, clopidogrel, azithromycin, St John's wort, etc should be used cautiously along with Ranidom RD tablet.

Interactions with food items

Ranidom RD tablet should preferably be taken on an empty stomach at least 1 hour before meals.

Storage and disposal

• Store this medicine below 25°C in a clean and dry place, protected from direct sunlight, moisture and heat.
• Keep this medicine away from children and pets.

Frequently Asked Questions (FAQs)

What is the use of Ranidom RD tablet?

Ranidom RD tablet is used to treat gastroesophageal reflux disease (GERD) in adults when GERD does not respond to esomeprazole medicine alone. GERD is a condition that leads to acid regurgitating from the stomach into the food pipe, causing heartburn, chest discomfort and acidity.

Can Ranidom RD tablet be taken after food?

It should not be taken after food as food interacts with the absorption of this medicine. Hence, it should preferably be taken at least 1 hour before food.

How much time does it take for this medicine to act?

It takes approximately 1 hour after taking a dose for this medicine to act. However, it varies from person to person due to varied physiology.

Can we take Ranidom RD tablet along with Itraconazole?

You should avoid taking this medicine with itraconazole as it reduces the absorption of itraconazole, reducing its effect. You should consult your doctor before taking Itraconazole when on treatment with this medicine.

What is the composition of the Ranidom RD?

Ranidom RD contains a combination of domperidone and esomeprazole, an anti-reflux medicine.

For how long do I need to take the Ranidom RD?

Your doctor will decide the frequency and duration of the treatment with Ranidom RD after accessing your condition. You should not stop taking this medicine before the treatment is complete neither you should take it for too long.

When should I take my Ranidom Rd tablet?

You should take Ranidom Rd one hour before the meal, preferably in the morning. These tablets should be swallowed whole with water.

What are the side effects of Ranidom Rd?

Headache, dizziness, nausea, vomiting, stomach pain are a few common side effects of Ranidom Rd. However, these symptoms are usually mild and resolve on their own. Also, it is not important that everyone experience the same.

Can the use of Ranidom-RD tablet cause dry mouth?

Yes, you may experience dry mouth after taking Ranidom-RD tablet. If you experience dry mouth, it is advised to drink plenty of water at regular intervals. Avoid staying dehydrated.