Stemetil 12.5mg/ml Injection

Stemetil Injection is a prescription medicine used in the treatment of nausea, vomiting and post-operative emesis & migraines. It's also used to alleviate anxiety and dizziness caused by ear illnesses. Stemetil Injection contains prochlorperazine as an active ingredient.

It works by blocking the action of dopamine, a chemical messenger in the brain that regulates thoughts and mood and stimulates the vomiting centre responsible for nausea and vomiting. Therefore, Stemetil Injection shows an antiemetic action by inhibiting dopamine. Stemetil Injection should be taken in dosage and duration as advised by your doctor.

There are also many side effects associated with this medicine, so it is advised to take it after the doctor’s consultation and dosage must be carefully monitored. Do not stop taking this medicine suddenly without consulting your doctor, as it can cause clinical worsening of your condition or may lead to withdrawal symptoms.

Dosage

Overdose

Overdose of Stemetil Injection causes symptoms like agitation, difficulty falling asleep or staying asleep, drooling, uncontrollable shaking of a part of the body, shuffling walk, hypotension, tachycardia, sleepiness and coma (loss of consciousness for a while). If you have these overdose symptoms, contact your doctor and seek emergency medical treatment from the nearby hospital.

Missed a Dose

Since Stemetil Injection is administered by a qualified healthcare professional, ideally in a hospital, the likelihood of missing a dose is very low. However, it is advised to contact your doctor immediately if you miss a scheduled dose of this medicine.

Mode of Action

How Does It Work?

Stemetil Injection contains prochlorperazine 12.5 mg as an active ingredient. Prochlorperazine belongs to the antipsychotic class of medicine. It works by blocking the action of dopamine, a chemical messenger in the brain that regulates thoughts and mood. Dopamine is also responsible for controlling the vomiting centre in the brain which is responsible for nausea and vomiting. Therefore, Stemetil Injection shows an antiemetic action by inhibiting dopamine.

Directions for Use

• Stemetil Injection should not be used unless prescribed by a doctor.
• Stemetil Injection should be administered under the supervision of a healthcare professional.
• Before administering the injection, it should be diluted with equal amounts of compatible diluent.
• Administer Stemetil Injection precisely as advised by your doctor. Do not exceed the prescribed dosage, even if you cannot feel its effects.
• To avoid the development of tolerance or dependence, the lowest effective dose will be prescribed for the shortest time possible.
• Elderly persons should be given a lower dose of this medicine.
• Do not consume other medications while taking this injection; consult your doctor.
• Do not suddenly quit this medication as it can cause withdrawal effects.

Precautions and Warnings

Pregnancy

Can I take Stemetil Injection during pregnancy?

Stemetil Injection is not recommended for pregnant women. This medicine should be used by pregnant women only if necessary. Limited studies have shown an increased risk of severe side effects in newborns. Consult your doctor for safe usage of the medication.

Breast Feeding

Can I take Stemetil Injection while breastfeeding?

Stemetil Injection is not recommended during breastfeeding. It may get excreted into breast milk and can affect the baby. Consult your doctor and discuss the potential risks and benefits of this medicine. Your doctor may advise you to discontinue breastfeeding or prescribe low doses if you continue breastfeeding.

Driving

Can I drive if I have taken Stemetil Injection?

Stemetil Injection may cause side effects that could affect your ability to drive. The tablet may decrease alertness, affect your vision and can cause dizziness, lightheadedness. Avoid driving if you are experiencing the side effects mentioned above after taking this medicine

Alcohol

Can I consume alcohol with the Stemetil Injection?

No, do not consume alcohol with Stemetil Injection, as it increases the severity of side effects like dizziness, drowsiness, lethargy, blurred vision, liver injury, etc. It also worsens the symptoms for which you are using this medicine.

Other General Warnings

Talk to your doctor if

• You are allergic reaction after taking Stemetil Injection
• You experience any severe side effects
• You are pregnant or planning to conceive
• Your symptoms do not improve or there is worsening of your condition
• You have seizures or epilepsy
• You are over 65 years old.
• You have diabetes or high sugar levels in your blood (hyperglycaemia)

Contraindications

• If you are allergic to a component of Stemetil Injection i.e prochlorperazine.
• If you have glaucoma
• If you have a history of Seizure or fits
• If you are a pregnant or breastfeeding mother
• If you have liver disease
• If you have kidney disease
• If you have any respiratory illnesses
• If you have any severe heart condition

Side effects

• Headache
• Constipation
• Drowsiness
• Blurred vision
• Dry mouth
• Stuffed nose

Interactions

Interactions with other medicines

• Tell your doctor and pharmacist what prescription and non-prescription medications, herbal products, vitamins and nutritional supplements, you are consuming or plan to take as there is a chance of drug interaction. Many medicines can interact with Stemetil Injection, making it less effective or increasing side effects. This includes-
• Adrenaline (medicine that is used to treat life-threatening allergic responses)
• Medications to aid sleep like sedatives
• Amitriptyline like antidepressants
• Levodopa and other Parkinson's disease medications
• Carbamazepine (medication used to treat fits)
• Amphetamines (type of stimulant used to treat ADHD - Attention Deficit Hyperactivity Disorder)
• Lithium (a medicine used to treat certain types of mental disorders)
• Medicines to moderate heartbeat-like amiodarone, disopyramide, propranolol, and quinidine
• Medications for blood pressure like doxazosin, terazosin, guanethidine, and clonidine
• Anticholinergic (used to treat irritable bowel syndrome, asthma, and incontinence)

Storage and disposal

Store Stemetil Injection at room temperature in a cool and dry area, away from sunlight. Keep the medication away from children and pet animals in a closed or locked cabinet. Do not remove the medicine from its packing and store it within its original packaging. Disposal- Do not flush medicines down into the toilet or throw them into the dustbin unless instructed to do so. Medicines disposed of in this manner may pollute or contaminate the environment. Properly dispose of this product when it is expired or no longer required.

Frequently Asked Questions (FAQs)

How long does it take for Stemetil Injection to show a desirable effect?

Currently, there is no established data about the amount of time the Stemetil Injection takes to show its desired effect. Follow your doctor's advice regarding the duration of medicine and Do not stop taking medicines on your own after the improvement of symptoms

Does taking Stemetil Injection than the recommended dose will resolve my symptoms quickly?

No, do not take Stemetil Injection more than the recommended dose as it may lead to overdose or may worsen your condition. Consult your doctor if you have any queries about the doses and do not increase the dose on your own.

Are there any specific tests to be performed while using Stemetil Injection?

While you are taking Stemetil Injection, your doctor may run some tests on you on a regular basis. Blood tests and an electric cardiogram (ECG) may be performed to ensure that your heart is in good functional order.